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Clinical Application of Magnifying Endoscopy with Narrow-Band Imaging in the Stomach

Yao K

Magnifying endoscopy with narrow-band imaging (M-NBI) can visualize superficial microanatomies in the stomach. The normal morphology of the microanatomy visualized by M-NBI differs according to the part of the stomach....
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E-learning system to improve the endoscopic diagnosis of early gastric cancer

Yao K, Yao T, Uedo N, Doyama H, Ishikawa H, Nimura S, Takahashi Y

We developed three e-learning systems for endoscopists to acquire the necessary skills to improve the diagnosis of early gastric cancer (EGC) and demonstrated their usefulness using randomized controlled trials. The...
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Magnified Endoscopic Findings of Multiple White Flat Lesions: A New Subtype of Gastric Hyperplastic Polyps in the Stomach

Hasegawa R, Yao K, Ihara S, Miyaoka M, Kanemitsu , Chuman K, Ikezono G, Hirano A, Ueki T, Tanabe H, Ota A, Haraoka S, Iwashita A

BACKGROUND/AIMS:: While the occurrence of multiple whitish flat elevated lesions (MWFL) was first reported in 2007, no studies on MWFL have been published to date. The present retrospective observational study...
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Optical Microangiography: High-Definition Magnification Colonoscopy with Narrow Band Imaging (NBI) for Visualizing Mucosal Capillaries and Red Blood Cells in the Large Intestine

Yao K, Anagnostopoulos GK, Jawhari AU, Kaye PV, Hawkey CJ, Ragunath K

  • KMID: 2009151
  • Gut Liver.
  • 2008 Jun;2(1):14-18.
BACKGROUND/AIMS: Recent advances in zoom endoscopy have enabled the subepithelial capillary network (SECN) in different organs of the gastrointestinal tract to be visualized. Ex vivo studies have suggested that the...
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Image-Enhanced Endoscopy and Its Corresponding Histopathology in the Stomach

Doyama H, Nakanishi H, Yao K

In recent years, the technological innovation and progress of endoscopic equipment have been remarkable, and various endoscopic observation techniques have been developed. Among them, representative techniques are magnified observation and...
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Clinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study

Imamura K, Yao K, Nimura S, Kanemitsu T, Miyaoka M, Ono Y, Ueki T, Tanabe H

Background/Aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC. Methods: This single-center...
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White Opaque Substance, a New Optical Marker on Magnifying Endoscopy: Usefulness in Diagnosing Colorectal Epithelial Neoplasms

Yamasaki K, Hisabe T, Yao K, Ishihara H, Imamura K, Yasaka T, Tanabe H, Iwashita A, Ueki T

Background/Aims: A white substance that is opaque to endoscopic light is sometimes observed in the epithelium during narrowband imaging with magnifying endoscopy of gastric or colorectal epithelial neoplasms. This prospective...
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Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancer

Ono Y, Yao K, Takaki Y, Ishikawa S, Imamura K, Koga A, Ohtsu K, Kanemitsu T, Miyaoka M, Hisabe T, Ueki T, Ota A, Tanabe H, Haraoka S, Nimura S, Iwashita A, Sato S, Wakasaki R

Background/Aims: Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous...
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Association between occurrence of multiple white and flat elevated gastric lesions and oral proton pump inhibitor intake

Hasegawa R, Yao K, Kanemitsu T, Arima H, Hirase T, Hiratsuka Y, Takeda K, Imamura K, Ohtsu K, Ono Y, Miyaoka M, Hisabe T, Ueki T, Tanabe H, Ohta A, Nimura S

Background/Aims: Multiple white and flat elevated lesions (MWFL) that develop from the gastric corpus to the fornix may be strongly associated with oral antacid intake. Therefore, this study aimed to...
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Discogenic Axial Back Pain: Is There a Role for Nucleoplasty?

Kumar NS, Shah SM, Tan BW, Juned S, Yao K

STUDY DESIGN: A prospective observational study. PURPOSE: To evaluate the role of nucleoplasty in the management of discogenic axial back pain; to determine the influence of concordant pain during provocative discography,...
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Trough level of infliximab is useful for assessing mucosal healing in Crohn's disease: a prospective cohort study

Koga A, Matsui T, Takatsu N, Takada Y, Kishi M, Yano Y, Beppu T, Ono Y, Ninomiya K, Hirai F, Nagahama T, Hisabe T, Takaki Y, Yao K, Imaeda H, Andoh A

BACKGROUND/AIMS: Decreased trough levels of infliximab (TLI) and antibodies to infliximab (ATI) are associated with loss of response (LOR) in Crohn's disease. Two prospective studies were conducted to determine whether...
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Histological Architecture of Gastric Epithelial Neoplasias That Showed Absent Microsurface Patterns, Visualized by Magnifying Endoscopy with Narrow-Band Imaging

Chuman K, Yao K, Kanemitsu T, Nagahama T, Miyaoka M, Takahashi H, Imamura K, Hasegawa R, Ueki T, Tanabe H, Haraoka S, Iwashita A

Background/Aims: The objective of this study was to elucidate the histological structure of the absent microsurface patterns (MSPs) that were visualized by magnifying endoscopy with narrow-band imaging (M-NBI). Methods: The study...
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Non-atrophic gastric mucosa is an independently associated factor for superficial non-ampullary duodenal epithelial tumors: a multicenter, matched, case-control study

Kawasaki A, Tsuji K, Uedo N, Kanesaka T, Miyamoto H, Gushima R, Minoda Y, Ihara E, Amano R, Yao K, Naito Y, Aoyagi H, Iwasaki T, Uchita K, Arima H, Doyama H

Background/Aims: The etiology of superficial non-ampullary duodenal epithelial tumors (SNADETs) remains unclear. Recent studies have reported conflicting associations between duodenal tumor development and Helicobacter pylori infection or endoscopic gastric mucosal...
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Risk factors for severity of colonic diverticular hemorrhage

Kinjo K, Matsui T, Hisabe T, Ishihara H, Kojima T, Chuman K, Yasukawa S, Beppu T, Koga A, Ishikawa S, Kishi M, Takatsu N, Hirai F, Yao K, Ueki T, Washio M

BACKGROUND/AIMS: Colonic diverticular hemorrhage (DH) was a rare disease until the 1990s, and its incidence has increased rapidly since 2000 in Japan. In recent years, colonic DH has been the...
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