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Apoptosis and Expression of p53, bcl-2 and c-myc Proteins in Benign Prostatic Hyperplasia and Prostate Cancer

Lee SJ, Kim SW, Cho YH

  • KMID: 1583467
  • Korean J Urol.
  • 2000 Aug;41(8):917-924.
No abstract available.
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Pediatric B-cell Lymphoma, Unclassifiable, With Intermediate Features Between Those of Diffuse Large B-cell Lymphoma and Burkitt Lymphoma: A Report of Two Cases

Zhang S, Wilson D, Czader M

No abstract available.
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Detection of MYC gene amplification in malignant lymphomas

Park CK, Lee CG, Lee JD

The role of oncogene or tumor supressor gene in Epstein-Barr virus (EBV) associated malignant lymphomas (MLs) is poorly understood. We examined 36 MLs (21 EBV positive and 15 EBV...
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Isochromosome 1q in Childhood Burkitt Lymphoma: The First Reported Case in Korea

Rim JH, Kim HS, Shin S, Park SJ, Choi JR

No abstract available.
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c-Myc expression is related with cell proliferation and associated with poor clinical outcome in human gastric cancer

Han S, Kim HY, Park K, Cho HJ, Lee MS, Kim HJ, Kim YD

We underwent protein assay for Myc expression in 76 human gastric cancer tissues using immunohistochemistry. Expression of Myc protein was analyzed according to proliferative indices measured by flow cytometry. Levels...
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Immunohistochemical Study on bcl-2, c-myc, EGFR as Predictable Factor for Radiosensitivity in Early Glottic Cancer

Cho JS, Lim SC, Na AS, Seo DJ, Kim CK

  • KMID: 2275999
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Feb;46(2):134-138.
BACKGROUND AND OBJECTIVES: The radiotherapy or surgery is the main treatment modality for early glottic cancer. The advantage of radiotherapy is the preservation of good voice quality after treatment but...
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Exogenous c-Myc Blocks Differentiation and Improves Expansion of Human Erythroblasts In vitro

Geiler C, Andrade I, Greenwald

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the blood supply for transfusion treatment. The production of red blood cells from hematopoietic stem cells...
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c-Myc-Induced Long Non-Coding RNA Small Nucleolar RNA Host Gene 7 Regulates Glycolysis in Breast Cancer

Zhang L, Fu Y, Guo H

PURPOSE: Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported...
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Effect of growth factors on the expression of proto-oncogenes c-fos and c-myc in FRTL-5 cell line

Yoon HY, Oh SK, Yi KH, Cho BY, Koh CS

This study was performed to prove the hypothesis that oncogene expressions would have the same patterns with those of cellular growth to growth factors in FRTL-5 cells. Ribonucleic acids of...
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Suppression of Aurora-A oncogenic potential by c-Myc downregulation

Yang S, He S, Zhou X, Liu M, Zhu H, Wang Y, Zhang W, Yan S, Quan L, Bai J, Xu N

The abnormality of serine/threonine kinase Aurora-A is seen in many types of cancers. Although in physiological context it has been shown to play a vital role in cellular mitosis, how...
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Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex

Jeon WJ, Kim SH, Seo MS, Kim Y, Kang UG, Juhnn YS, Kim YS

Repeated electroconvulsive seizure (ECS), a model for electroconvulsive therapy (ECT), exerts neuroprotective and proliferative effects in the brain. This trophic action of ECS requires inhibition of apoptotic activity, in addition...
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Expressions of bcl-2 and c-myc Protooncogenes and Their Relationship to the Proliferation and Apoptosis in Uterine Cervical Intraepithelial Neoplasia and Cervical Carcinoma

Kim BG, Lee HP

  • KMID: 2269753
  • Korean J Obstet Gynecol.
  • 1999 Aug;42(8):1755-1768.
bcl-2 prevents cell death from a wide variety of stimuli and provides survival of cells with accumulated genetic alterations and c-myc can promote both cell proliferation and cell death through...
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Expression of Caspase-3 and c-myc in Non-Small Cell Lung Cancer

Yoo JY, Kim CH, Song SH, Shim BY, Jeong YJ, Ahn MI, Kim S, Cho DG, Jo MS, Cho KD, Cho HJ, Kang SJ, Kim HK

  • KMID: 1804565
  • Cancer Res Treat.
  • 2004 Oct;36(5):303-307.
PURPOSE: Caspase-3 is a cysteine protease that plays an important role in the process of apoptotic cell death, but little has been studied clinically on caspase-3 in lung cancer. Increased...
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Changes in the expression of c-myc, RB and tyrosine-phosphorylated proteins during proliferation of NIH 3T3 cells induced by hyaluronic acid

Moon SO, Lee JH, Kim TJ

  • KMID: 754984
  • Exp Mol Med.
  • 1998 Mar;30(1):29-33.
We have shown that hyaluronic acid stimulates the proliferation of quiescent NIH 3T3 cells. We have shown that treatment of 1 mg/ml hyaluronic acid results in increase of tyrosine phosphorylation of two...
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Association of castration-dependent early induction of c-myc expression with a cell proliferation of the ventral prostate gland in rat

Lim K, Park C, Kim YK, Yun KA, Son MY, Lee YC, Park JI, Lee JH, Sul CK, Lee CS, Park SK, Hwang BD

  • KMID: 755102
  • Exp Mol Med.
  • 2000 Dec;32(4):216-221.
The protooncogene c-myc is known to be associated with both cell proliferation and apoptosis. The possible cellular affects of castration on the ventral prostate gland of rat as...
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CD5-negative Blastoid Variant Mantle Cell Lymphoma with Complex CCND1/IGH and MYC Aberrations

Seok Y, Kim J, Choi JR, Kim YR, Park SJ, Kim SJ, Song J, Lee KA

The coexistence of CCND1/IGH and MYC rearrangements in mantle cell lymphoma (MCL) is a rare finding associated with a very poor prognosis. In this study, a patient with blastoid variant...
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Gastrokine 1 Expression in the Human Gastric Mucosa Is Closely Associated with the Degree of Gastritis and DNA Methylation

Choi WS, Seo HS, Song KY, Yoon JH, Kim O, Nam SW, Lee JY, Park WS

  • KMID: 2372476
  • J Gastric Cancer.
  • 2013 Dec;13(4):232-241.
PURPOSE: Gastrokine 1 plays an important role in gastric mucosal defense. Additionally, the Gastrokine 1-miR-185-DNMT1 axis has been shown to suppress gastric carcinogenesis through regulation of epigenetic alteration. Here, we...
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beta-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells

Yi YW, Kang HJ, Bae EJ, Oh S, Seong YS, Bae I

An F-box protein, beta-TrCP recognizes substrate proteins and destabilizes them through ubiquitin-dependent proteolysis. It regulates the stability of diverse proteins and functions as either a tumor suppressor or an oncogene....
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Silencing of Long Non-Coding RNA MALAT1 Promotes Apoptosis of Glioma Cells

Xiang J, Guo S, Jiang S, Xu Y, Li J, Li L, Xiang J

The metastasis-associated lung adenocarcinoma transcription 1 (MALAT1) is a highly conserved long non-coding RNA (lncRNA) gene. However, little is known about the pathological role of lncRNA MALAT1 in glioma. In...
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Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique

Kim HJ, Jeong J, Park S, Jin YW, Lee SS, Lee SB, Choi D

BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects...
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