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In vitro evaluation of anti-herpesviral activity of derivatives of nucleic acids and their precursors

Lee CK, Rha ZS, Kim HS

  • KMID: 1688546
  • J Korean Soc Virol.
  • 1992 Mar;22(1):69-76.
No abstract available.
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Genotyping for RhD and RhCEce Antigens Using Free Circulating Nucleic Acids in Plasma and Serum

Chang HE, Hwang SM, Hong YJ, Han M, Park JS, Park KU, Song J, Han KS

BACKGROUND: The Rh blood group includes several antigens, of which D, C, E, c, and e are clinically important. Although nucleic acids from whole blood can be used for Rh...
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Circulating Cell-free Tumor Nucleic Acids in Gastric Cancer

Lee HJ, Lee SM

Gastric cancer is still the leading cause of cancer deaths, especially in Asian countries. Recently, many studies have analyzed cell-free nucleic acids (cfNAs) circulating in the blood, for the early...
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Circulating Tumor Cells and Extracellular Nucleic Acids in Breast Cancer

Ryu DW, Lee CH

Circulating tumor cells (CTCs) are defined as tumor cells circulating in the peripheral blood of patients, shed from either the primary tumor or from its metastases. The detection of circulating...
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Back to the Ends: Chromosomal DNA

Lee MH, Suh D

  • KMID: 2322080
  • J Korean Soc Pediatr Nephrol.
  • 2008 Apr;12(1):1-10.
Nucleic scids transfer the genetic information for serving a central biological purpose. The nucleic acids are polymers of nucleotides and they are mainly ribonucleic acid(RNA) and deoxyribonucleic acid(DNA). The nucleotides...
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Recent Advances in Biosensors for Nucleic Acid and Exosome Detection

Fu Z, Lu YC, Lai JJ

Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied...
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Analysis of Nucleic Acids in Malassezia furfur Serovars A, B and C

Kim HU, Ashbee R

BACKGROUND: Recently Malassezia (M.) furfur fungemia has been increasingly recognized in premature infants and adults receiving parenteral nutrition. Accordingly, analysis of nucleic acids in M. furfur serovars and strain typing...
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Noninvasive Prenatal Diagnosis Using Cell-free Fetal Nucleic Acids in the Maternal Circulation

Lim JH, Park SY, Ryu HM

  • KMID: 2280859
  • Korean J Perinatol.
  • 2012 Sep;23(3):143-151.
Cell-free fetal nucleic acids in the maternal circulation can be broadly divided into fetal DNA and RNA that originate from apoptotic placenta cells. Cell-free fetal nucleic acids can be detected...
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Effect of L-Ascorbic Acid and DL-alpha-Tocopherol on the Activation and Binding of 2-Acetylaminofluorene to Rat Liver Nuclear Macromolecules in Vivo

Hong YS

Male Sprangue-Dawley rats which had been administered either ascorbic acid or DL-alpha-tocopherol for 4 weeks were injected intraperitoneally with a single dose of(9-14C)-2-acetylaminofluorens(AAF) 3.5hr before sacrifice. The activation and binding...
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Pathogenesis and promising non-invasive markers for preeclampsia

Kim YJ

Preeclampsia is one of the leading causes of maternal mortality/morbidity and preterm delivery in the world, affecting 3% to 5% of pregnant women. The pathophysiology of preeclampsia likely involves both...
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Extracellular vesicles in renal physiology and clinical applications for renal disease

Kwon SH

Many cells in the nephron release extracellular vesicles (EVs). EVs envelop nucleic acids, proteins, and lipids. The surfaces of EVs express donor cell-specific markers, ligands, and major histocompatibility complex molecules....
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Development and Application of Cell-penetrating Peptides

Yi H

Intracellular transduction of hydrophilic macromolecules has been problematic owing to the biochemical restriction imposed by lipid bilayer of the cytoplasmic membrane. Several technologies have been developed to improve the intracellular...
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Liquid biopsy? A recent breakthrough in noninvasive bladder cancer surveillance

Kang M, Ku JH

No abstract available.
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Application of radiation technology in vaccines development

Seo HS

One of the earliest methods used in the manufacture of stable and safe vaccines is the use of chemical and physical treatments to produce inactivated forms of pathogens. Although these...
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A Case of Secondary Gout Associated with Essential Thrombocythemia

Kim YM, Lee S, Lee JE, Lim DH, Kim I, Park KW, Lee SI

Gouty arthritis is a metabolic disorder characterized by hyperuricemia, deposition of monosodium urate crystal in the joints, and recurrent episodes of acute inflammatory arthritis. Depending on the actual causes of...
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Age-specific Prevalence of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus Type 2, and Mycoplasma hyopneumoniae in Korea Pig Farms

Kang I, Ham H

Porcine respiratory disease complex (PRDC) continues to be a significant economic problem to the swine industry. Porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus (PRRSV), and Mycoplasma...
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Microbe-derived extracellular vesicles as a smart drug delivery system

Yang J, Kim EK, McDowell A, Kim YK

The human microbiome is known to play an essential role in influencing host health. Extracellular vesicles (EVs) have also been reported to act on a variety of signaling pathways, distally...
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Studies on the Development of Viral Detection Markers for the Quality Control of Blood

Kim Y, Lee JH, Kim Y

According to the serological screening methods of antigen-antibody reaction such as ELISA, it has been known that the complete detection of viral infections of HBV, HCV, and HIV-1 viruses in...
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Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism

Kim H, Park YJ

Cancer metabolism is considered as one of major cancer hallmarks. It is important to understand cancer-specific metabolic changes and its impact on cancer biology to identify therapeutic potentials. Among cancer-specific...
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Dependence of RIG-I Nucleic Acid-Binding and ATP Hydrolysis on Activation of Type I Interferon Response

Baek YM, Yoon S, Hwang YE, Kim DE

Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase...
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