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Letter to the Editor: Presence of Evolutionary Pressures or Genotyping Error

Saadat M

No abstract available.
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The Role of Microsatellite Instability in Development of Gastric Lymphoma

Jung HY

  • KMID: 1113460
  • Korean J Gastroenterol.
  • 2006 Mar;47(3):238-240.
No abstract availble.
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Study on Association between an H-RAS Gene Polymorphism and Gastric Cancer Development

Oh JH

No abstract available.
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Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines

Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW

Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of...
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What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer?

Lee SK

No abstract available.
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The Expression of ERCC1, RRM1, and BRCA1 in Breast Cancer According to the Immunohistochemical Phenotypes

Kim D, Jung W, Koo JS

We studied the expression of BRCA1, ERCC1, and RRM1 which play an important role in DNA repair systems in breast cancer. Immunohistochemical staining for EGFR, BRCA1, ERCC1, and RRM1 were...
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Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms

Kim YB, Lee SY, Kim JH, Sung IK, Park HS, Shim CS, Han HS

BACKGROUND/AIMS: Microsatellite instability (MSI) plays a crucial role in gastrointestinal carcinogenesis. The aim of this study was to clarify whether MSI is a useful marker for predicting synchronous gastric and...
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Role of Long Non-coding Ribonucleic Acid in Gastrointestinal Cancer

Park CH, Lee SK

With the improvement of high-throughput genomic technology such as microarray and next-generation sequencing over the last ten to twenty year, we have come to know that the portion of the...
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Loss of Y Chromosome in the Malignant Peripheral Nerve Sheet Tumor of a Patient with Neurofibromatosis Type 1

Jeong SY, Park SJ, Lee SJ, Park HJ, Kim HJ

Neurofibromatosis type 1 (NF1) is one of the most commonly inherited autosomal dominant disorders. In order to determine whether genomic alterations and/or chromosomal aberrations involved in the malignant progression of...
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Next generation sequencing and urologic cancer

Kim SK, Kim WJ

No abstract available.
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Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis

Kim HS, Shen Q, Nam SW

A growing body of evidence suggests that epigenetic modifications are promising potential mechanisms in cancer research. Among the molecules that mediate epigenetic mechanisms, histone deacetylases (HDACs) are critical regulators of...
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Letter to the Editor: Detection of EML4-ALK and Other ALK Fusion Genes in Lung Cancer: A Lesson from the Leukemia Fusion Gene Analysis and Future Application

Park TS, Jeon YL, Lee HJ, Jeong JH, Kim SY, Cho EH, Marschalek R, Meyer C

No abstract available.
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Position statements on genetic test for peritoneal, ovarian, and fallopian tubal cancers: Korean Society of Gynecologic Oncology (KSGO)

Choi MC, Lim MC, Suh DH, Song YJ, Kim TJ, Chang SJ, Kim JW, Korean Society of Gynecologic Oncology

No abstract available.
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Clinically relevant genetic characterization of prostate tumors: How close are we to the goal?

Tolkach Y, Imkamp F, Godin K, Van Poppel H

Substantial efforts are being made in research on the molecular genetic characterization of prostate cancer. The number of fundamental research programs in prostate cancer molecular biology and genetics is overwhelming....
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Characterization of Mutator Pathway in Younger-age-onset Colorectal Adenocarcinomas

Roh SA, Kim HC, Kim JS, Kim JC

The high-frequency microsatellite instability (MSI-H) phenotype, frequently identified in hereditary nonpolyposis colorectal cancer (HNPCC), also accounts for approximately 15% of sporadic colorectal cancers. Microsatellite instability (MSI) occurs from the mutational...
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Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus

Park PG, Lee H

Germ-line mutations in BRCA2 predispose to early-onset cancer. Homozygous mutant mouse, which has Brca2 truncated in exon 11 exhibit paradoxic occurrence of growth retardation and development of thymic lymphomas. However,...
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Cytogenetic analysis of meningiomas

Cho JH, Gong GY, Yu ES, Whang CJ, Jee KJ, Lee IC

Cytogenetic analysis of 4 cases of meningiomas from 3 male and 1 female patients is reported. One of male patients suffered from neurofibromatosis type 2. Histologically, the meningiomas were...
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DNA flow cytometry in pheochromocytoma and paraganglioma

Jung WH, Yang WI, Park C, Choi IJ

Flow cytometric DNA analysis was performed on 19 adrenal pheochromocytomas and 6 extra-adrenal paragangliomas in parallel with clinical and histopathological review to determine the usefulness of this technique to predict...
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MiR-152 suppresses the proliferation and invasion of NSCLC cells by inhibiting FGF2

Cheng Z, Ma R, Tan W, Zhang L

MicroRNAs (miRNAs) regulate the proliferation and metastasis of cancer cells. Here, we showed that miR-152 was downregulated in non-small-cell lung cancer (NSCLC) tissues and cell lines. Overexpression of miR-152 suppressed...
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Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer

Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS

Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution...
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