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Multimodal Composite Iron Oxide Nanoparticles for Biomedical Applications

Pillarisetti S, Uthaman S, Huh KM, Koh YS, Lee S, Park IK

BACKGROUND: Iron oxide nanoparticles (IONPs) are excellent candidates for biomedical imaging because of unique characteristics like enhanced colloidal stability and excellent in vivo biocompatibility. Over the last decade, material scientists...
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Bleaching of stained resin using nitrogen doped-TiOâ‚‚ nanoparticles

Moon K, Jung SB, Seol HJ, Kang JS, Kwon YH

There has been increasing use of the Hâ‚‚Oâ‚‚-based teeth bleaching agents. The purpose of this study was to evaluate the bleaching effectiveness of the laser irradiation combined with nitrogen doped-TiOâ‚‚...
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Preparation and characterization of rutile phase TiOâ‚‚ nanoparticles and their cytocompatibility with oral cancer cells

Dong VP, Trang NT, Yoo H

In the present study, rutile phase titanium dioxide nanoparticles (R-TiO₂ NPs) were prepared by hydrolysis of titanium tetrachloride in an aqueous solution followed by calcination at 900℃. The composition of...
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Fine dust and eye health

Choi SY, Eom Y, Song JS, Kim HM

This paper aims to make recommendations for the management of eye health related to fine dust exposure. Fine dust is one of the biggest problems related to air pollution in...
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Investigating the Sonodynamic-Radiosensitivity Effect of Gold Nanoparticles on HeLa Cervical Cancer Cells

Shanei A, Akbari-Zadeh H

BACKGROUND: In this article, we estimated the combined effect of radiotherapy (RT) with ultrasound (US) wave and the ability of gold nanoparticles (GNPs) to improve their combined therapeutic effects. METHODS: At...
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Acanthamoeba in Southeast Asia – Overview and Challenges

Bunsuwansakul C, Mahboob T, Hounkong K, Laohaprapanon S, Chitapornpan S, Jawjit S, Yasiri A, Barusrux S, Bunluepuech K, Sawangjaroen N, Salibay CC, Kaewjai C, de Lourdes Pereira M, Nissapatorn V

Acanthamoeba, one of free-living amoebae (FLA), remains a high risk of direct contact with this protozoan parasite which is ubiquitous in nature and man-made environment. This pathogenic FLA can cause...
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Bacillus Calmette-Guérin (BCG)-Cell Wall Skeleton as Immunotherapeutic Option for BCG-Refractory Superficial Bladder Cancer

Whang YM, Yoon DH, Hwang GY, Choi YW, Chang IH

Although intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most successful cancer immunotherapy for superficial bladder cancer, the serious side effects are frequently arisen by using live mycobacteria....
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Color alterations of a PMMA resin for fixed interim prostheses reinforced with silica nanoparticles

Kotanidis , Kontonasaki E, Koidis P

PURPOSE: The aim of the present study was to evaluate the color changes of an autopolymerizing PMMA resin used for interim fixed restorations, reinforced with SiO2 nanoparticles. MATERIALS AND METHODS: Silica...
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Comparative study of indocyanine green combined with blue dye with methylene blue only and carbon nanoparticles only for sentinel lymph node biopsy in breast cancer

Qin X, Yang M, Zheng X

PURPOSE: The combination of indocyanine green and methylene blue (ICG + MB) was reported to be an efficient tracer method in sentinel lymph node biopsy (SLNB). However, whether this method...
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Extraordinary Response of Metastatic Pancreatic Cancer to Chemotherapy

Shin DW, Kim J, Lee JC, Kim J, Hwang JH

A 58-year-old woman presented with right flank and back pain for one month. After undergoing an abdominal computed tomography (CT), she was referred to our hospital. The abdominal CT showed...
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Polymeric Nanoparticles Containing Both Antigen and Vitamin D₃ Induce Antigen-Specific Immune Suppression

Jung HH, Kim SH, Moon JH, Jeong SU, Jang S, Park CS, Lee CK

The active form of vitamin D3, 1,25-dihydroxyvitamin D₃ (aVD₃), is known to exert beneficial effects in the treatment of autoimmune diseases because of its immunosuppressive effects. However, clinical application of...
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Preparation and Characterization of Nanocomposite Scaffolds (Collagen/β-TCP/SrO) for Bone Tissue Engineering

Goodarzi H, Hashemi-Najafabadi S, Baheiraei , Bagheri F

BACKGROUND: Nowadays, production of nanocomposite scaffolds based on natural biopolymer, bioceramic, and metal ions is a growing field of research due to the potential for bone tissue engineering applications. METHODS: In...
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Induction of Melanoma Cell-Selective Apoptosis Using Anti-HER2 Antibody-Conjugated Gold Nanoparticles

Jeon HJ, Choi BB, Park KH, Hwang DS, Kim UK, Kim GC

PURPOSE: This study was conducted to verify the induction and mechanism of selective apoptosis in G361 melanoma cells using anti-HER2 antibody-conjugated gold nanoparticles (GNP-HER2). MATERIALS AND METHODS: Following GNP-HER2 treatment of...
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Influence of silver nanoparticles on resin-dentin bond strength durability in a self-etch and an etch-and-rinse adhesive system

Jowkar Z, Shafiei F, Asadmanesh E, Koohpeima

OBJECTIVES: This study evaluated the effect of dentin pretreatment with silver nanoparticles (SNPs) and chlorhexidine (CHX) on the microshear bond strength (µSBS) durability of different adhesives to dentin. MATERIALS AND METHODS:...
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Human Neural Stem Cells: Translational Research for Neonatal Hypoxic-Ischemic Brain Injury

Shin JE, Han J, Lim JH, Eun HS, Park KI

Neonatal hypoxic-ischemic (HI) brain injury is a major cause of neonatal mortality and long-term neurodevelopmental disabilities. Although promising neuroprotective interventions have been studied, the current management of HI brain injury...
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Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation

Piao H, Kim MH, Cui M, Choi G, Choy JH

BACKGROUND: Alendronate (AL), a drug for inhibiting osteoclast-mediated bone-resorption, was intercalated into an inorganic drug delivery nanovehicle, layered double hydroxide (LDH), to form a new nanohybrid, AL-LDH, with 1:1 heterostructure...
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Diagnostic value of magnetic resonance imaging using superparamagnetic iron oxide for axillary node metastasis in patients with breast cancer: a meta-analysis

Lee RD, Park JG, Ryu DW, Kim YS

OBJECTIVES: Identification of axillary metastases in breast cancer is important for staging disease and planning treatment, but current techniques are associated with a number of adverse events. This report evaluates...
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A Comparison of the Effects of Silica and Hydroxyapatite Nanoparticles on Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/Chitosan Nanofibrous Scaffolds for Bone Tissue Engineering

Raeisdasteh Hokmabad V, Davaran S, Aghazadeh , Alizadeh E, Salehi R, Ramazani A

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(ε-caprolactone)-poly(ethylene...
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Long-circulating and target-specific distributions of cyanine 5.5-labeled hyaluronic acid nanoparticles in mouse organs during 28 days after a single administration

Yun TS, Lin C, Yon JM, Park SG, Gwon LW, Lee JG, Baek IJ, Nahm SS, Lee BJ, Yun YW, Nam SY

Although hyaluronic acid (HA) has been developed as a nanoparticle (NP; 320–400 nm) for a drug delivery system, the tissue targeting efficacy and the pharmacokinetics of HA-NPs are not yet...
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Characterization of Tetrodes Coated with Au Nanoparticles (AuNPs) and PEDOT and Their Application to Thalamic Neural Signal Detection in vivo

Lee D, Moon HC, Tran BT, Kwon DH, Kim YH, Jung SD, Joo JH, Park YS

Tetrodes, consisting of four twisted micro-wires can simultaneously record the number of neurons in the brain. To improve the quality of neuronal activity detection, the tetrode tips should be modified...
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