Epidemiol Health.  2015;37:e2015020. 10.4178/epih/e2015020.

Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance

• Kandi V
• Kandi S

• KMID: 2380657
• DOI: http://doi.org/10.4178/epih/e2015020

Abstract

OBJECTIVES
The emergence of multi-drug resistance among various microbial pathogens has been a cause of serious concern to the medical world, limiting the choice of antibiotics. Considering that it may take decades to synthesize new antimicrobial drugs that combat resistant pathogens, the search for alternatives to conventional antimicrobial agents has begun.
METHODS
In his paper we attempted to review the physico-chemical properties of nanoparticles, their modes of action and potential use in medicine and research with special reference to antimicrobial properties.
RESULTS
Nanomolecules and nanoparticles have in recent years been extensively studied for their utility not only as antibiotics but also as vehicles to carry antibiotics or other agents such as cancer chemotherapeutics to target sites and limit damage to host cells.
CONCLUSION
Nanomolecules were positively evaluated for their antimicrobial activities. Anti-biofilm activities of nanoparticles, utility of nanomaterials as carrier agents of drugs signifies their importance in medicine and research.

Keyword

Nanomolecules; Nanoparticles; Nanomedicine; Anti-bacterial agents

MeSH Terms

Anti-Bacterial Agents*
Anti-Infective Agents
Drug Resistance, Multiple*
Nanomedicine
Nanoparticles
Nanostructures
Anti-Bacterial Agents
Anti-Infective Agents