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Molecular epidemiology and characterization of Streptococcus mutans strains in Korea

Kim SY, Bae IK, Lee JH, Shin JH, Kim JB

OBJECTIVES: We investigated the characteristics of Streptococcus mutans in the national culture collection from Korea. Twenty-nine (dental plaque, n=27; endodontic infections, n=1; blood, n=1) isolates were included in this study. METHODS:...
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Pharmacokinetics/Pharmacodynamics models of veterinary antimicrobial agents

Luo W, Chen D, Wu M, Li Z, Tao Y, Liu Q, Pan Y, Qu W, Yuan Z, Xie S

Misuse and abuse of veterinary antimicrobial agents have led to an alarming increase in bacterial resistance, clinical treatment failure, and drug residues. To address these problems, consistent and appropriate dosage...
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Management of Typhoid Fever – Clinical and Historical Perspectives in Korea

Chang MS, Woo JH, Kim S

Typhoid fever, showed a dramatic decrease in its incidence from 56 per 100,000 population just after Korea's independence to
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Prescription of Antibiotics for Adults with Acute Infectious Diarrhea in Korea: A Population-based Study

Lee HJ, Park KH, Park DA, Park J, Bang BW, Lee SS, Lee EJ, Kim YJ, Hong SK, Kim YR

BACKGROUND: Acute infectious diarrhea (AID) is a commonly observed condition globally. Several studies recommend against the use of empiric antibiotic therapy for AID, except in some cases of travelers' diarrhea....
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Changes in the Treatment Strategies for Helicobacter pylori Infection in Children and Adolescents in Korea

Jun JS, Seo JH, Park JS, Rhee KH, Youn HS

The policies developed for the treatment of Helicobacter pylori infection in adults may not be the most suitable ones to treat children and adolescents. Methods used to treat children and...
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Antifungal Mechanism of Action of Lauryl Betaine Against Skin-Associated Fungus Malassezia restricta

Do E, Lee HG, Park M, Cho YJ, Kim DH, Park SH, Eun D, Park T, An S, Jung WH

Betaine derivatives are considered major ingredients of shampoos and are commonly used as antistatic and viscosity-increasing agents. Several studies have also suggested that betaine derivatives can be used as antimicrobial...
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Principles of selecting appropriate antimicrobial agents

Choi SM, Lee DG

The inappropriate use of antimicrobial agents results in collateral damages such as treatment failure, an increased frequency of adverse events related to antimicrobial agents, the emergence of resistant bacteria, and...
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Epidemiology of Staphylococcus aureus Bacteremia in Children at a Single Center from 2002 to 2016

Lim S, Ha SG, Tchah H, Jeon IS, Ryoo E, Son DW, Cho HJ, Sun YH, Kim HJ, Ahn JM, Cho HK

PURPOSE: We aimed to investigate the epidemiological characteristics of Staphylococcus aureus bacteremia in Korean children. METHODS: We retrospectively collected and analyzed data from the medical records of the patients with S....
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RND efflux pump systems in Acinetobacter, with special emphasis on their role in quorum sensing

Subhadra B, Oh MH, Choi CH

Acinetobacter is an important opportunistic, multidrug resistant pathogen causing majority of nosocomial infections worldwide. The multidrug resistance is attributed by a plethora of efflux pumps and the overexpression of the...
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Antimicrobial Susceptibility Patterns of Anaerobic Bacterial Clinical Isolates From 2014 to 2016, Including Recently Named or Renamed Species

Byun JH, Kim M, Lee Y, Lee K, Chong Y

BACKGROUND: Anaerobic bacterial resistance trends may vary across regions or institutions. Regional susceptibility patterns are pivotal in the empirical treatment of anaerobic infections. We determined the antimicrobial resistance patterns of...
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Optimal antimicrobial therapy and antimicrobial stewardship in sepsis and septic shock

Seok H, Park DW

The management of sepsis and septic shock remains challenging. The aim is to apply the optimal antimicrobial therapy and antimicrobial stewardship to patients in state of sepsis or septic shock....
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Evaluation of in vitro antimicrobial susceptibility of Bacillus anthracis strains isolated during anthrax outbreaks in Italy from 1984 to 2017

Manzulli V, Fasanella , Parisi A, Serrecchia L, Donatiello A, Rondinone , Caruso M, Zange S, Tscherne A, Decaro N, Pedarra C, Galante D

Anthrax, caused by Bacillus anthracis, is a non-contagious infectious disease that affects a wide range of animal species (primarily ruminants) including humans. Due to the often-fatal outcome in humans, quick...
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Relationship between personal care products usage and triclosan exposure: the second Korean National Environmental Health Survey (KoNEHS 2012–2014)

Park M, Kim S, Kim Y, Nam DJ, Ryoo JH, Lim S

BACKGROUND: We aimed to find the exposure level of triclosan (TCS), a known endocrine disruptor, related to the use of personal care products using a nationally representative data of the...
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Concurrent Use of Sulfonylureas and Antimicrobials of the Elderly in Korea: A Potential Risk of Hypoglycemia

Lee S, Ock M, Kim H

BACKGROUND: Previous studies have noted that the simultaneous use of sulfonylureas and antimicrobials, which is common, could increase the risk of hypoglycemia. In particular, an age of 65 years or...
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Augmented renal clearance

Atkinson A

Adding to the complexity of caring for critically ill patients is the fact that many of them have a creatinine clearance that exceeds 130 mL/min/1.73 m². This phenomenon, termed augmented...
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The efficiency of topical anesthetics as antimicrobial agents: A review of use in dentistry

Kaewjiaranai T, Srisatjaluk RL, Sakdajeyont W, Pairuchvej V, Wongsirichat N

Topical anesthetics are commonly used in oral & maxillofacial surgery to control pain in the oral cavity mucosa before local anesthetic injection. These anesthetic agents come in many forms, developed...
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Surgical hand antisepsis: experimental study

Izaguirre , Govela A, Delgado I, Troncoso C, Parra M, Viaña EA

PURPOSE: Nosocomial infections account for one of the most serious complications in hospitalized patients around the world. Surgical site infections have significant economic implications, and surgical antisepsis plays an important...
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Biological and Genetic Characteristics of Clinically Isolated Enterobacter cloacae with Multidrug Resistance

Kim JJ, Koo SH

BACKGROUND: From January 2014 to December 2015, 69 clones of Enterobacter cloacae showing multidrug resistance to six classes of antimicrobial agents were collected from two medical centers in Korea. METHODS: Minimum...
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Antibiotics Induced Seizures and Encephalopathy

Cho KH

Drug-induced seizures and delirium are common among patients with critical illnesses, especially those in an intensive care unit. With an increase in the use of potent, broad-spectrum antibiotics, the etiology...
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Versatile Scalp Donor Split Thickness Skin Graft in Burn Patients

Kim DC, Yu SH, Shin CH, Kim JH

PURPOSE: It is well known the advantages of scalp donor split thickness skin graft(STSG) in deep burn wound because of its scarless donor healing, and good color match in face....
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