- Novel glutathione-containing dry-yeast extracts inhibit eosinophilia and mucus overproduction in a murine model of asthma
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Kim YH, Choi YJ, Lee EJ, Kang MK, Park SH, Kim DY, Oh H, Park SJ, Kang YH
- KMID: 2395300
- Nutr Res Pract.
- 2017 Dec;11(6):461-469.
- doi: 10.4162/nrp.2017.11.6.461
BACKGROUND/OBSECTIVE: Airway inflammation by eosinophils, neutrophils and alveolar macrophages is a characteristic feature of asthma that leads to pathological subepithelial thickening and remodeling. Our previous study showed that oxidative stress... -
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- MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease
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Yoo KS, Choi HS, Jun DW, Lee HL, Lee OY, Yoon BC, Lee KG, Paik SS, Kim YS, Lee J
- KMID: 2412085
- Gut Liver.
- 2016 Sep;10(5):851-858.
- doi: 10.5009/gnl15600
BACKGROUND/AIMS: Gallstone pathogenesis is linked to mucin hypersecretion and bacterial infection. Several mucin genes have been identified in gallbladder epithelial cells (GBECs). We investigated MUC expression in cholesterol-associated gallbladder disease... -
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- TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients
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Zhang Y, Wang X, Wang H, Jiao J, Li Y, Fan E, Zhang L, Bachert C
- KMID: 2166684
- Allergy Asthma Immunol Res.
- 2015 Jul;7(4):367-375.
- doi: 10.4168/aair.2015.7.4.367
PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP), a mainly Th2 cytokine-mediated disease, often involves mucus secretion. Recent evidence suggests that transmembrane protein 16A (TMEM16A), a calcium-activated Cl- channel (CaCC), can... -
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- A Melting Method for RNA Extraction from the Mucosal Membrane of the Mouse Middle Ear
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Seo YJ, Kim SH, Moon IS, Choi JY
- KMID: 2070030
- Yonsei Med J.
- 2015 Mar;56(2):497-502.
- doi: 10.3349/ymj.2015.56.2.497
PURPOSE: There is much confusion surrounding the methods of RNA extraction from the middle ear mucosa of mice. In this study, we worked to develop a "melting method," which is... -
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- Oral Lovastatin Attenuates Airway Inflammation and Mucus Secretion in Ovalbumin-Induced Murine Model of Asthma
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Liou CJ, Cheng PY, Huang WC, Chan CC, Chen MC, Kuo ML, Shen JJ
- KMID: 2260178
- Allergy Asthma Immunol Res.
- 2014 Nov;6(6):548-557.
- doi: 10.4168/aair.2014.6.6.548
PURPOSE: Lovastatin is an effective inhibitor of cholesterol synthesis. A previous study demonstrated that lovastatin can also suppress airway hyperresponsiveness (AHR) in murine model of asthma. We aimed to investigate... -
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- A Case of Primary Retroperitoneal Mucinous Cystadenoma Arising from the Retropancreatic Area
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Nam YJ, Kim TN, Kim KH, Gu MG, Lee JY
- KMID: 1730931
- Korean J Gastroenterol.
- 2014 Mar;63(3):187-190.
- doi: 10.4166/kjg.2014.63.3.187
Primary retroperitoneal mucinous cystadenoma is an extremely uncommon tumor, even though mucinous cystadenoma often develops in the ovary and less frequently in the pancreas. A 21-year-old female was admitted to... -
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- Effect of Prunetin on TNF-alpha-Induced MUC5AC Mucin Gene Expression, Production, Degradation of IkappaB and Translocation of NF-kappaB p65 in Human Airway Epithelial Cells
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Ryu J, Lee HJ, Park SH, Sikder MA, Kim JO, Hong JH, Seok JH, Lee CJ
- KMID: 2320469
- Tuberc Respir Dis.
- 2013 Nov;75(5):205-209.
BACKGROUND: We investigated whether prunetin significantly affects tumor necrosis factor-alpha (TNF-alpha)-induced MUC5AC mucin gene expression, production, inhibitory kappa B (IkappaB) degradation and nuclear factor kappa B (NF-kappaB) p65 translocation in... -
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- An Inverse Relationship between the Expression of the Gastric Tumor Suppressor RUNX3 and Infection with Helicobacter pylori in Gastric Epithelial Dysplasia
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Chung WC, Jung SH, Joo KR, Kim MJ, Youn GJ, Kim Y, Lee JS, Lee H, Jung JH, Lee YK
- KMID: 1712329
- Gut Liver.
- 2013 Nov;7(6):688-695.
BACKGROUND/AIMS: This study was performed to determine the association between RUNX3 expression and Helicobacter pylori infection in premalignant gastric lesions. METHODS: We examined 107 patients with gastric epithelial dysplasia who had... -
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- Cholesterol Depletion in Cell Membranes of Human Airway Epithelial Cells Suppresses MUC5AC Gene Expression
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Song KJ, Kim NH, Lee GB, Kim JH, Kwon JH, Kim KS
- KMID: 1727882
- Yonsei Med J.
- 2013 May;54(3):679-685.
- doi: 10.3349/ymj.2013.54.3.679
PURPOSE: If cholesterol in the cell membrane is depleted by treating cells with methyl-beta-cyclodextrin (MbetaCD), the activities of transmembrane receptors are altered in a cell-specific and/or receptor-specific manner. The proinflammatory... -
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- Berberine Suppresses Interleukin-1beta-Induced MUC5AC Gene Expression in Human Airway Epithelial Cells
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Kim KR, Kim NH, Park Y, Kim JH, Lee EJ, Kim KS
- KMID: 2297593
- J Rhinol.
- 2011 Nov;18(2):116-121.
OBJECTIVES: The aim of this study was to investigate whether berberine suppresses interleukin (IL)-1beta-induced MUC5AC gene expression in human airway epithelial cells and, if so, to determine which mitogen-activated protein... -
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- Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells
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Jiang DP, Perelman J, Kolosov VP, Zhou XD
- KMID: 1785964
- J Korean Med Sci.
- 2011 Jun;26(6):778-784.
- doi: 10.3346/jkms.2011.26.6.778
Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial... -
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- Effects of Curcumin and Genistein on Phorbol Ester or Tumor Necrosis Factor-alpha-Induced Mucin Production from Human Airway Epithelial Cells
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Lee SY, Lee HJ, Lee JW, Jeon BK, Kim JO, Lee CJ
- KMID: 1442851
- Tuberc Respir Dis.
- 2011 Mar;70(3):218-223.
- doi: 10.4046/trd.2011.70.3.218
BACKGROUND: We investigated whether curcumin and genistein affect the MUC5AC mucin production from human airway epithelial cells that is induced by phorbol 12-myristate 13-acetate (PMA) or tumor necrosis factor-alpha (TNF-alpha). METHODS:... -
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- Regulation of Tumor Necrosis Factor-alpha-induced Airway Mucin Production and Gene Expression by Carbenoxolone, Prunetin, and Silibinin
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Lee HJ, Lee SY, Jeon BK, Lee JW, Lee MN, Kim JO, Lee CJ
- KMID: 2319442
- Tuberc Respir Dis.
- 2010 Nov;69(5):348-353.
BACKGROUND: In this study, we tried to investigate whether carbenoxolone, prunetin, and silibinin affect tumor necrosis factor (TNF)-alpha-induced MUC5AC mucin production and gene expression from human airway epithelial cells. METHODS: Confluent... -
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- Expression of MUC3, MUC5AC, MUC6 and Epidermal Growth Factor Receptor in Gallbladder Epithelium according to Gallstone Composition
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Kim HJ, Kim JS, Kim KO, Park KH, Yim HJ, Kim JY, Yeon JE, Park JJ, Shim JJ, Byun KS, Bak YT, Lee CH
- KMID: 772564
- Korean J Gastroenterol.
- 2003 Oct;42(4):330-336.
BACKGROUND/AIMS: Gallbladder (GB) mucin is one of the key factors in the gallstone formation. However, there is little information about the diversity of mucin secretion according to the stone composition.... -
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