- Standards for Organoids
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Ahn SJ
- KMID: 2556228
- Int J Stem Cells.
- 2024 May;17(2):99-101.
- doi: 10.15283/ijsc24043
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- Human Pluripotent Stem Cell-Derived Retinal Organoids: A Viable Platform for Investigating the Efficacy of Adeno-Associated Virus Gene Therapy
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Na HJ, Kwon JE, Kim SH, Ahn J, Kwon OS, Chung KS
- KMID: 2556238
- Int J Stem Cells.
- 2024 May;17(2):204-211.
- doi: 10.15283/ijsc23071
With recent advances in adeno-associated virus (AAV)-based gene therapy, efficacy and toxicity screening have become essential for developing gene therapeutic drugs for retinal diseases. Retinal organoids from human pluripotent stem... -
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- Guidelines for Packaging, Transport, and Storage of Source Cells for Organoids
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Lee S, Kwon D, Lee HB, Jeon S, Park C, Kim TS, Lee JH, Oh IU, Ahn SJ
- KMID: 2556230
- Int J Stem Cells.
- 2024 May;17(2):113-119.
- doi: 10.15283/ijsc24042
This report presents guidelines for the systematic management of packaging, storage, transportation, and traceability of source cells used for organoid research. Given the important role of source cells in organoid... -
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- Essential Guidelines for Manufacturing and Application of Organoids
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Ahn SJ, Lee S, Kwon D, Oh S, Park C, Jeon S, Lee JH, Kim TS, Oh IU
- KMID: 2556229
- Int J Stem Cells.
- 2024 May;17(2):102-112.
- doi: 10.15283/ijsc24047
An organoid is a self-organized three-dimensional structure derived from stem cells that mimics the structure, cell composition, and functional characteristics of specific organs and tissues and is used for evaluating... -
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- Guidelines for Manufacturing and Application of Organoids: Kidney
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Kang HM, Kim DS, Kim YK, Shin K, Ahn SJ, Jung CR
- KMID: 2556233
- Int J Stem Cells.
- 2024 May;17(2):141-146.
- doi: 10.15283/ijsc24040
Recent advancements in organoid technology have led to a vigorous movement towards utilizing it as a substitute for animal experiments. Organoid technology offers versatile applications, particularly in toxicity testing of... -
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- Energy Metabolism in Human Pluripotent Stem and Differentiated Cells Compared Using a Seahorse XF96 Extracellular Flux Analyzer
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Kim HK, Song Y, Kye M, Yu B, Park SB, Kim JH, Moon SH, Choi H, Moon JS, Oh JS, Lee MR
- KMID: 2556237
- Int J Stem Cells.
- 2024 May;17(2):194-203.
- doi: 10.15283/ijsc23167
Evaluating cell metabolism is crucial during pluripotent stem cell (PSC) differentiation and somatic cell reprogramming as it affects cell fate. As cultured stem cells are heterogeneous, a comparative analysis of... -
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- Guidelines for Manufacturing and Application of Organoids: Skin
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Lee S, Rim YA, Kim J, Lee SH, Park HJ, Kim H, Ahn SJ, Ju JH
- KMID: 2556236
- Int J Stem Cells.
- 2024 May;17(2):182-193.
- doi: 10.15283/ijsc24045
To address the limitations of animal testing, scientific research is increasingly focused on developing alternative testing methods. These alternative tests utilize cells or tissues derived from animals or humans for... -
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- Guidelines for Manufacturing and Application of Organoids: Liver
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Moon HR, Mun SJ, Kim TH, Kim H, Kang D, Kim S, Shin JH, Choi D, Ahn SJ, Son MJ
- KMID: 2556231
- Int J Stem Cells.
- 2024 May;17(2):120-129.
- doi: 10.15283/ijsc24044
Recent amendments to regulatory frameworks have placed a greater emphasis on the utilization of in vitro testing platforms for preclinical drug evaluations and toxicity assessments. This requires advanced tissue models... -
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- Guidelines for Manufacturing and Application of Organoids: Heart
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Lee HA, Woo DH, Lim DS, Oh J, Kim CY, Bae ON, Ahn SJ
- KMID: 2556232
- Int J Stem Cells.
- 2024 May;17(2):130-140.
- doi: 10.15283/ijsc24046
Cardiac organoids have emerged as invaluable tools for assessing the impact of diverse substances on heart function. This report introduces guidelines for general requirements for manufacturing cardiac organoids and conducting cardiac... -
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- Guidelines for Manufacturing and Application of Organoids: Lung
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Lim K, Lee MO, Choi J, Kim JH, Kim EM, Woo CG, Chung C, Cho YH, Hong SH, Cho YJ, Ahn SJ
- KMID: 2556234
- Int J Stem Cells.
- 2024 May;17(2):147-157.
- doi: 10.15283/ijsc24041
The objective of standard guideline for utilization of human lung organoids is to provide the basic guidelines required for the manufacture, culture, and quality control of the lung organoids for... -
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- Guidelines for Manufacturing and Application of Organoids: Brain
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Kwak T, Park SH, Lee S, Shin Y, Yoon KJ, Cho SW, Park JC, Yang SH, Cho H, Im HI, Ahn SJ, Sun W, Yang JH
- KMID: 2556235
- Int J Stem Cells.
- 2024 May;17(2):158-181.
- doi: 10.15283/ijsc24056
This study offers a comprehensive overview of brain organoids for researchers. It combines expert opinions with technical summaries on organoid definitions, characteristics, culture methods, and quality control. This approach aims... -
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