- Glutathione Dynamics in the Tumor Microenvironment: A Potential Target of Cancer Stem Cells and T Cells
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Park Y, Jeong EM
- KMID: 2558605
- Int J Stem Cells.
- 2024 Aug;17(3):270-283.
- doi: 10.15283/ijsc24060
Glutathione (GSH), the main cellular antioxidant, dynamically influences tumor growth, metastasis, and resistance to therapy in the tumor microenvironment (TME), which comprises cancer cells, immune cells, stromal cells, and non-cellular... -
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- Navigating the Landscape of Intestinal Regeneration: A Spotlight on Quiescence Regulation and Fetal Reprogramming
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Oh SJ, Seo Y, Kim HS
- KMID: 2558601
- Int J Stem Cells.
- 2024 Aug;17(3):213-223.
- doi: 10.15283/ijsc23176
Tissue-specific adult stem cells are pivotal in maintaining tissue homeostasis, especially in the rapidly renewing intestinal epithelium. At the heart of this process are leucine-rich repeat-containing G protein-coupled receptor 5-expressing... -
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- Human Endometrial Regenerative Cells for Neurological Disorders: Hype or Hope?
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Momeni J, Naserzadeh E, Sepehrinezhad A, Ahmadabad RA, Negah SS
- KMID: 2558602
- Int J Stem Cells.
- 2024 Aug;17(3):224-235.
- doi: 10.15283/ijsc23091
Despite enormous efforts, no effective medication has been found to significantly halt or even slow the progression of neurological diseases, such as acquired (e.g., traumatic brain injury, spinal cord injury,... -
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- Pancreatic Diseases: Genetics and Modeling Using Human Pluripotent Stem Cells
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Lee Y, Lee K
- KMID: 2558604
- Int J Stem Cells.
- 2024 Aug;17(3):253-269.
- doi: 10.15283/ijsc24036
Pancreas serves endocrine and exocrine functions in the body; thus, their pathology can cause a broad range of irreparable consequences. Endocrine functions include the production of hormones such as insulin... -
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- The Role of Exosomes from Mesenchymal Stem Cells in Spinal Cord Injury: A Systematic Review
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Wang H, Zhao C, Rong Q, Cao J, Chen H, Li R, Zhang B, Xu P
- KMID: 2558603
- Int J Stem Cells.
- 2024 Aug;17(3):236-252.
- doi: 10.15283/ijsc23092
Spinal cord injury (SCI) is a serious nervous system disease that usually leads to the impairment of the motor, sensory, and autonomic nervous functions of the spinal cord, and it... -
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- Establishing Three-Dimensional Explant Culture of Human Dental Pulp Tissue
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Seo EJ, Park S, Lee E, Huh YH, Ha YE, Tigyi GJ, Jeong T, Jang IH, Shin J
- KMID: 2558610
- Int J Stem Cells.
- 2024 Aug;17(3):330-336.
- doi: 10.15283/ijsc23105
Mesenchymal stem cells in the dental tissue indicate a disposition for differentiation into diverse dental lineages and contain enormous potential as the important means for regenerative medicine in dentistry. Among... -
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- Cytoplasmatic Localization of Six1 in Male Testis and Spermatogonial Stem Cells
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Qin M, Ma L, Du W, Chen D, Luo G, Liu Z
- KMID: 2558607
- Int J Stem Cells.
- 2024 Aug;17(3):298-308.
- doi: 10.15283/ijsc23093
Sine oculis homeobox 1 (Six1) is an important factor for embryonic development and carcinoma malignancy. However, the localization of Six1 varies due to protein size and cell types in different... -
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- Impaired Osteogenesis in Human Induced Pluripotent Stem Cells with Acetaldehyde Dehydrogenase 2 Mutations
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Lim J, Han H, Jung SI, Rim YA, Ju JH
- KMID: 2558606
- Int J Stem Cells.
- 2024 Aug;17(3):284-297.
- doi: 10.15283/ijsc23151
Acetaldehyde dehydrogenase 2 (ALDH2) is the second enzyme involved in the breakdown of acetaldehyde into acetic acid during the process of alcohol metabolism. Roughly 40% of East Asians carry one... -
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- Suppression of Glioblastoma Stem Cell Potency and Tumor Growth via LRRK2 Inhibition
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Park S, Kim KH, Bae YH, Oh YT, Shin H, Kwon HJ, Kim CI, Kim SS, Choi HG, Park JB, Lee BD
- KMID: 2558609
- Int J Stem Cells.
- 2024 Aug;17(3):319-329.
- doi: 10.15283/ijsc24032
Leucine-rich repeat kinase 2 (LRRK2), a large GTP-regulated serine/threonine kinase, is well-known for its mutations causing late-onset Parkinson’s disease. However, the role of LRRK2 in glioblastoma (GBM) carcinogenesis has not... -
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- Human Endometrium Derived Mesenchymal Stem Cells with Aberrant NOD1 Expression Are Associated with Ectopic Endometrial Lesion Formation
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Li C, Luo S, Guo A, Su Y, Zhang Y, Song Y, Liu M, Wang L, Zhang Y
- KMID: 2558608
- Int J Stem Cells.
- 2024 Aug;17(3):309-318.
- doi: 10.15283/ijsc22200
Nucleotide-binding oligomerization domain 1 (NOD1), a cytosolic pattern recognition receptor protein, plays a crucial role in innate immune responses. However, the functional expression of NOD1 in mesenchymal stem cells (MSCs)... -
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