- Stem Cells for the Regeneration of Tendon and Ligament: A Perspective
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Im GI, Kim TK
- KMID: 2508907
- Int J Stem Cells.
- 2020 Nov;13(3):335-341.
- doi: 10.15283/ijsc20091
Tendons are structures that connect muscles to the bones in our body and transmit the force generated by contraction of the muscles to the bones. Ligaments are structures that connect... -
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- The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review
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Zhang Q, Han Z, Zhu Y, Chen J, Li W
- KMID: 2508905
- Int J Stem Cells.
- 2020 Nov;13(3):312-325.
- doi: 10.15283/ijsc20097
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance. Finding... -
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- Hematopoietic Stem Cells Culture, Expansion and Differentiation: An Insight into Variable and Available Media
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Yadav P, Vats R, Bano A, Bhardwaj R
- KMID: 2508906
- Int J Stem Cells.
- 2020 Nov;13(3):326-334.
- doi: 10.15283/ijsc19157
Owing to differentiation and self-renewal capacity, hematopoietic stem cells clasp potentiality to engender all blood cell types, leading to their immense competence to play a diverse role in therapeutic applications.... -
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- The Progress and Clinical Application of Breast Cancer Organoids
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Yu J, Huang W
- KMID: 2508903
- Int J Stem Cells.
- 2020 Nov;13(3):290-304.
- doi: 10.15283/ijsc20082
Breast cancer is the malignant tumor with the highest incidence in women. Nowadays, the objects in vitro of models of this disease are mainly from breast cancer cell lines and... -
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- Human Placenta-Derived ECM Supports Tri-Lineage Differentiation of Human Induced Pluripotent Stem Cells
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Murchison AC, Odanga JJ, Treadwell ML, Breathwaite EK, Weaver JR, Lee JB
- KMID: 2508917
- Int J Stem Cells.
- 2020 Nov;13(3):432-438.
- doi: 10.15283/ijsc20074
Human pluripotent stem cells (hPSCs) hold great promise for future applications in drug discovery and cell therapies. hPSC culture protocols require specific substrates and medium supplements to support cell expansion... -
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- Isolation and Characterization of Human Suture Mesenchymal Stem Cells In Vitro
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Kong L, Wang Y, Ji Y, Chen J, Cui J, Shen W
- KMID: 2508911
- Int J Stem Cells.
- 2020 Nov;13(3):377-385.
- doi: 10.15283/ijsc20024
Background and Objectives: Cranial sutures play a critical role in adjustment of skull development and brain growth. Premature fusion of cranial sutures leads to craniosynostosis. The aim of the current... -
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- KLF4 Regulates Goblet Cell Differentiation in BMI1＋ Reserve Intestinal Stem Cell Lineage during Homeostasis
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Katano T, Bialkowska AB, Yang VW
- KMID: 2508916
- Int J Stem Cells.
- 2020 Nov;13(3):424-431.
- doi: 10.15283/ijsc20048
Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor, expressed in villus cells of the intestinal epithelium, that promotes cellular differentiation and tissue homeostasis. Previous studies suggest that BMI1＋ cells... -
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- In Vitro Study of Adipose-Derived Mesenchymal Stem Cells Transduced with Lentiviral Vector Carrying the Brain-Derived Neurotrophic Factor Gene
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Nan D, Dou X, Qi Y, Zhang W, He G, Zhang X
- KMID: 2508912
- Int J Stem Cells.
- 2020 Nov;13(3):386-393.
- doi: 10.15283/ijsc20038
Brain-derived neurotrophic factor (BDNF) exerts its survival-promoting effects on photoreceptors and retinal ganglion cells, however, delivery systems with little-to-no side effect are needed to sustain its controlled release and long-term... -
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- Screening of Integrin Heterodimers Expressed Functionally on the Undifferentiated Spermatogonial Stem Cells in the Outbred ICR Mice
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Park HJ, Yun JI, Kim M, Choi K, Lee E, Lee ST
- KMID: 2508909
- Int J Stem Cells.
- 2020 Nov;13(3):353-363.
- doi: 10.15283/ijsc20061
Background and Objectives: Outbred mice are widely used in toxicology, pharmacology, and fundamental biomedical research. However, there have been no reports of in vitro culture systems for spermatogonial stem cells... -
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- miR-29a in Exosomes from Bone Marrow Mesenchymal Stem Cells Inhibit Fibrosis during Endometrial Repair of Intrauterine Adhesion
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Tan Q, Xia D, Ying X
- KMID: 2508915
- Int J Stem Cells.
- 2020 Nov;13(3):414-423.
- doi: 10.15283/ijsc20049
Background and Objectives: Bone marrow mesenchymal stem cells (BMSCs) is an ideal source of stem cells in the treatment of intrauterine adhesion. Exosomes are a type of membrane vesicle and... -
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- Cdo Is Required for Efficient Motor Neuron Generation of Embryonic Stem Cells
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Kim H, Lee SY, Jeong HJ, Kang JS, Cho H, Leem YE
- KMID: 2508908
- Int J Stem Cells.
- 2020 Nov;13(3):342-352.
- doi: 10.15283/ijsc20037
Background and Objectives: The directed differentiation of pluripotent stem cells into motor neurons is critical for the development of disease modelling and therapeutics to intervene degenerative motor neuron diseases. Cell... -
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- Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver
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Jun JH, Jung J, Kim JY, Hwang SG, Bae SH, Kim GJ
- KMID: 2508914
- Int J Stem Cells.
- 2020 Nov;13(3):404-413.
- doi: 10.15283/ijsc20052
Background and Objectives: Liver cirrhosis is accompanied by abnormal vascular shunts. The Wnt pathway is essential for endothelial cell survival and proliferation. C-reactive protein (CRP), which is produced by hepatocyte,... -
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- Bone Marrow-Derived Mesenchymal Stem Cells Isolated from Patients with Cirrhosis and Healthy Volunteers Show Comparable Characteristics
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Lim YL, Eom YW, Park SJ, Hong T, Kang SH, Baik SK, Park KS, Kim MY
- KMID: 2508913
- Int J Stem Cells.
- 2020 Nov;13(3):394-403.
- doi: 10.15283/ijsc20072
Background and Objectives: Autologous or allogeneic bone marrow-derived mesenchymal stem cells (BMSCs) have been applied in clinical trials to treat liver disease. However, only a few studies are comparing the... -
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- Emerging Treatment Options of Regenerative Medicine in Severe Corona Virus/COVID 19 Infections
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Kumar A, Ghosh SB
- KMID: 2508904
- Int J Stem Cells.
- 2020 Nov;13(3):305-311.
- doi: 10.15283/ijsc20076
COVID-19 pandemic has brought the whole world stand still, locked down in their homes, infecting more than 8 million people, and many thousands (449,182) -have lost their lives across the... -
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- Intramyocardial Transplantation of Umbilical Cord Mesenchymal Stromal Cells in Chronic Ischemic Cardiomyopathy: A Controlled, Randomized Clinical Trial (HUC-HEART Trial)
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Ulus AT, Mungan C, Kurtoglu M, Celikkan FT, Akyol M, Sucu M, Toru M, Gul SS, Cinar O, Can A
- KMID: 2508910
- Int J Stem Cells.
- 2020 Nov;13(3):364-376.
- doi: 10.15283/ijsc20075
Background and Objectives: The HUC-HEART Trial (ClinicalTrials.gov Identifier: NCT02323477) was a controlled, prospective, phase I/II, multicenter, single-blind, three-arm randomized study of intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells... -
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