- Application of Nanotechnology in Targeting of Cancer Stem Cells: A Review
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Asghari F, Khademi R, Ranjbar FE, Malekshahi ZV, Majidi RF
- KMID: 2465894
- Int J Stem Cells.
- 2019 Jul;12(2):227-239.
- doi: 10.15283/ijsc19006
Cancer is increasingly apparent as a systems-level, network happening. The central tendency of malignant alteration can be described as a two-phase procedure, where an initial increase of network plasticity is... -
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- Mesenchymal Stem Cells from the Wharton's Jelly of the Human Umbilical Cord: Biological Properties and Therapeutic Potential
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Marino L, Castaldi M, Rosamilio , Ragni E, Vitolo R, Fulgione C, Castaldi S, Serio B, Bianco R, Guida M, Selleri C
- KMID: 2465893
- Int J Stem Cells.
- 2019 Jul;12(2):218-226.
- doi: 10.15283/ijsc18034
Wharton's jelly mesenchymal stem cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical... -
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- Regenerative Medicine of the Bile Duct: Beyond the Myth
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Buisson EM, Jeong J, Kim HJ, Choi D
- KMID: 2465890
- Int J Stem Cells.
- 2019 Jul;12(2):183-194.
- doi: 10.15283/ijsc18055
Cholangiopathies are rare diseases of the bile duct with high mortality rates. The current treatment for cholangiopathies is liver transplantation, but there are significant obstacles including a shortage of donors... -
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- Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells
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Jeong EM, Shin JW, Lim J, Kim JH, Kang H, Yin Y, Kim HM, Kim Y, Kim SG, Kang HS, Shin DM, Choi K, Kim IG
- KMID: 2465906
- Int J Stem Cells.
- 2019 Jul;12(2):367-379.
- doi: 10.15283/ijsc18151
Glutathione (GSH) is a major antioxidant in cells, and plays vital roles in the cellular defense against oxidants and in the regulation of redox signals. In a previous report, we... -
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- MBP-FGF2-Immobilized Matrix Maintains Self-Renewal and Myogenic Differentiation Potential of Skeletal Muscle Stem Cells
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Sah JP, Hao NT, Kim Y, Eigler T, Tzahor E, Kim SH, Hwang Y, Yoon JK
- KMID: 2465905
- Int J Stem Cells.
- 2019 Jul;12(2):360-366.
- doi: 10.15283/ijsc18125
The robust capacity of skeletal muscle stem cells (SkMSCs, or satellite cells) to regenerate into new muscles in vivo has offered promising therapeutic options for the treatment of degenerative muscle... -
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- Characterization and Differentiation of Circulating Blood Mesenchymal Stem Cells and the Role of Phosphatidylinositol 3-Kinase in Modulating the Adhesion
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Park YK, Heo SJ, Koak JY, Park GS, Cho TJ, Kim SK, Cho J
- KMID: 2465897
- Int J Stem Cells.
- 2019 Jul;12(2):265-278.
- doi: 10.15283/ijsc18136
Bone marrow mesenchymal stem cells (BM MSCs) can differentiate into multi-lineage tissues. However, obtaining BM MSCs by aspiration is difficult and can be painful; therefore peripheral blood (PB) MSCs might... -
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- A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells
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Yi TG, Cho YK, Lee HJ, Kim J, Jeon MS, Ham DS, Kim WC, Song SU
- KMID: 2465901
- Int J Stem Cells.
- 2019 Jul;12(2):315-330.
- doi: 10.15283/ijsc18098
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation. METHODS AND RESULTS:... -
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- Long Non-Coding RNA LINC00525 Promotes the Stemness and Chemoresistance of Colorectal Cancer by Targeting miR-507/ELK3 Axis
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Wang S, Li J, Yang X
- KMID: 2465904
- Int J Stem Cells.
- 2019 Jul;12(2):347-359.
- doi: 10.15283/ijsc19041
BACKGROUND AND OBJECTIVES: This study aims to explore the effects of a long non-coding RNA, LINC00525, on colorectal cancer (CRC) and its underlying molecular mechanisms. METHODS: The qPCR, MTT, colony formation,... -
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- Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Ischaemic-Reperfused Hearts in Adult Rats with Established Chronic Kidney Disease
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Hamed GM, Morsy WE, Abd-El Hamid MS, Hassan AA, Abu Zahra
- KMID: 2465900
- Int J Stem Cells.
- 2019 Jul;12(2):304-314.
- doi: 10.15283/ijsc18114
BACKGROUND AND OBJECTIVES: Bone marrow-derived mesenchymal stem cells (BM-MSCs) are adult multipotent non-haematopoietic stem cells that have regeneration potential. The current study aimed to detect the ability of BM-MSCs to... -
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- Enhanced Anti-Cancer Effects of Conditioned Medium from Hypoxic Human Umbilical Cord–Derived Mesenchymal Stem Cells
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Han KH, Kim AK, Jeong GJ, Jeon HR, Bhang SH, Kim DI
- KMID: 2465899
- Int J Stem Cells.
- 2019 Jul;12(2):291-303.
- doi: 10.15283/ijsc19002
BACKGROUND AND OBJECTIVES: There have been contradictory reports on the pro-cancer or anti-cancer effects of mesenchymal stem cells. In this study, we investigated whether conditioned medium (CM) from hypoxic human... -
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- FGF-17 from Hypoxic Human Wharton's Jelly-Derived Mesenchymal Stem Cells Is Responsible for Maintenance of Cell Proliferation at Late Passages
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Han KH, Kim MH, Jeong GJ, Kim AK, Chang JW, Kim DI
- KMID: 2465898
- Int J Stem Cells.
- 2019 Jul;12(2):279-290.
- doi: 10.15283/ijsc18042
BACKGROUND AND OBJECTIVES: Although it is well known that hypoxic culture conditions enhance proliferation of human mesenchymal stem cells, the exact mechanism is not fully understood. In this study, we... -
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- Hybrid Nanofiber Scaffold-Based Direct Conversion of Neural Precursor Cells/Dopamine Neurons
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Lim MS, Ko SH, Kim MS, Lee B, Jung HS, Kim K, Park CH
- KMID: 2465903
- Int J Stem Cells.
- 2019 Jul;12(2):340-346.
- doi: 10.15283/ijsc18123
The concept of cellular reprogramming was developed to generate induced neural precursor cells (iNPCs)/dopaminergic (iDA) neurons using diverse approaches. Here, we investigated the effects of various nanoscale scaffolds (fiber, dot,... -
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- Comparative Evaluation of Hormones and Hormone-Like Molecule in Lineage Specification of Human Induced Pluripotent Stem Cells
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Choi SA, An JH, Lee SH, Lee GH, Yang HJ, Jeong PS, Cha JJ, Lee S, Park YH, Song BS, Sim BW, Kim YH, Kim JS, Jin YB, Huh JW, Lee SR, Lee JH, Kim SU
- KMID: 2465895
- Int J Stem Cells.
- 2019 Jul;12(2):240-250.
- doi: 10.15283/ijsc18137
BACKGROUND AND OBJECTIVES: Proficient differentiation of human pluripotent stem cells (hPSCs) into specific lineages is required for applications in regenerative medicine. A growing amount of evidences had implicated hormones and... -
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- Efficacies of Stem Cell Therapies for Functional Improvement of the β Cell in Patients with Diabetes: A Systematic Review of Controlled Clinical Trials
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Hwang G, Jeong H, Yang HK, Kim HS, Hong H, Kim NJ, Oh IH, Yim HW
- KMID: 2465891
- Int J Stem Cells.
- 2019 Jul;12(2):195-205.
- doi: 10.15283/ijsc18076
BACKGROUND AND OBJECTIVES: This study was performed to investigate whether stem cell therapy enhances β cell function by meta-analysis with proper consideration of variability of outcome measurements in controlled trial... -
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- Angiotensin II and TGF-β1 Induce Alterations in Human Amniotic Fluid-Derived Mesenchymal Stem Cells Leading to Cardiomyogenic Differentiation Initiation
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GasiÅ«nienÄ— M, Petkus G, MatuzeviÄius D, Navakauskas D, NavakauskienÄ— R
- KMID: 2465896
- Int J Stem Cells.
- 2019 Jul;12(2):251-264.
- doi: 10.15283/ijsc18126
BACKGROUND AND OBJECTIVES: Human amniotic fluid-derived mesenchymal stem cells (AF-MSCs) may be a valuable source for cardiovascular tissue engineering and cell therapy. The aim of this study is to verify... -
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- Mesenchymal Stem Cell Transplantation Promotes Functional Recovery through MMP2/STAT3 Related Astrogliosis after Spinal Cord Injury
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Kim C, Kim HJ, Lee H, Lee H, Lee SJ, Lee ST, Yang SR, Chung CK
- KMID: 2465902
- Int J Stem Cells.
- 2019 Jul;12(2):331-339.
- doi: 10.15283/ijsc18133
BACKGROUND AND OBJECTIVES: Treatment with mesenchymal stem cells (MSC) in spinal cord injury (SCI) has been highlighted as therapeutic candidate for SCI. Although astrogliosis is a major phenomenon after SCI,... -
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- Adipose Tissue-Derived Stem Cell Therapy for Cavernous Nerve Injury-Induced Erectile Dysfunction in the Rat Model: A Systematic Review and Meta-Analysis Using Methodological Quality Assessment
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Park HJ, Jeong H, Park YH, Yim HW, Ha US, Hong SH, Kim SW, Kim NJ, Lee JY
- KMID: 2465892
- Int J Stem Cells.
- 2019 Jul;12(2):206-217.
- doi: 10.15283/ijsc18122
BACKGROUND AND OBJECTIVES: Few studies were evaluated the effect of blindness on outcome in animal models, though a potential effect of blinding has been reported in clinical trials. We evaluated... -
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