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The distribution of inositol 1,4,5-trisphosphate 3-kinase in rat cerebellum

Lee HK, Ko JP, Hwang SJ, Suh YS

  • KMID: 1686671
  • Korean J Anat.
  • 1993 Mar;26(1):94-102.
No abstract available.
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Distribution of inositol 1,4,5-trisphosphate 3-kinase in the cat brain by immunohistochemical study

Kim DH, Kim H, Hwang SJ, Hong HN, Suh YS

  • KMID: 1686601
  • Korean J Anat.
  • 1993 Dec;26(4):378-389.
No abstract available.
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The effect of kainic acid induced convulsions on the expression of inositol 1,4,5-trisphosphate receptor mRNA in the rat brain

Kim H, Ko SH, Kim CM, Rhyu IJ, Chung HS, Kim DY, Suh YS

  • KMID: 1937876
  • Korean J Anat.
  • 1998 Oct;31(5):645-654.
In this study, the effect of systemic administration of kainic acid (KA) on the expression of inositol 1,4,5-trisphosphate receptor mRNA in the rat brain was investigated with in situ hybridization...
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Calcium Signaling in Salivary Secretion

Kim JM, Lee SW, Park K

Calcium has versatile roles in diverse physiological functions. Among these functions, intracellular Ca²⁺ plays a key role during the secretion of salivary glands. In this review, we introduce the diverse...
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The effect of Ni2+ on the intracellular Ca2+ increase of the mouse early 2-cell embryos

Yoon SY, Lee EM, Bae IH

  • KMID: 2304560
  • Korean J Fertil Steril.
  • 2003 Dec;30(4):269-280.
OBJECTIVE: We reported the overcoming effect of Ni2+ on the in vitro 2-cell block of mouse embryos. In this study, we aim to investigate whether Ni2+ should induce intracellular Ca2+...
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Effects of Inositol 1,4,5-triphosphate on Osteoclast Differentiation in RANKL-induced Osteoclastogenesis

Son A, Kim MS, Jo H, Byun HM, Shin DM

The receptor activator of NF-kappaB ligand (RANKL) signal is an activator of tumor necrosis factor receptor-associated factor 6 (TRAF6), which leads to the activation of NF-kappaB and other signal transduction...
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Caffeine and 2-Aminoethoxydiphenyl Borate (2-APB) Have Different Ability to Inhibit Intracellular Calcium Mobilization in Pancreatic Acinar Cell

Choi KJ, Kim KS, Kim SH, Kim DK, Park HS

Inositol 1,4,5-trisphosphate receptors (InsP3Rs) modulate Ca2+ release from intracellular Ca2+ store and are extensively expressed in the membrane of endoplasmic/sarcoplasmic reticulum and Golgi. Although caffeine and 2-aminoethoxydiphenyl borate (2-APB) have...
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The Transcription Factor Mist1 Regulates the Cellular Polarity in Mouse Pancreatic Acinar Cells

Yang YM, Lee SI, Shin DM

  • KMID: 2009498
  • Int J Oral Biol.
  • 2012 Mar;37(1):37-41.
Pancreatic acinar cells exhibit a polarity that is characterized by the localization of secretory granules at the apical membrane. However, the factors that regulate cellular polarity in these cells are...
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Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium

Son A, Shin DM, Hong JH

The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The...
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Pharmacological evidence that cromakalim inhibits Ca2+ release from intracellular stores in porcine coronary artery

Rhim BY, Hong SH, Kim CD, Lee WS, Hong KW

  • KMID: 2285155
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):27-34.
In the present study, it was aimed to further identify the intracellular action mechanism of cromakalim and levcromakaliin in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine...
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Mercury Promotes Catecholamines Which Potentiate Mercurial Autoimmunity and Vasodilation: Implications for Inositol 1,4,5-Triphosphate 3-Kinase C Susceptibility in Kawasaki Syndrome

Yeter D, Deth R, Kuo HC

Previously, we reviewed biological evidence that mercury could induce autoimmunity and coronary arterial wall relaxation as observed in Kawasaki syndrome (KS) through its effects on calcium signaling, and that inositol...
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House Dust Mite Extract Induces PLC/IP3-dependent Ca2+ Signaling and IL-8 Expression in Human Gingival Epithelial Cells

Son GY, Son A, Park W, Shin DM

The gingival epithelium of the oral cavity is constantly exposed to exogenous stimuli such as bacterial toxins, allergens, and thermal changes. These exogenous stimuli are resisted by innate host defense...
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Inositol 5'-phosphatase, SHIP1 interacts with phospholipase C-gamma1 and modulates EGF-induced PLC activity

Song M, Kim MJ, Ha S, Park JB, Ryu SH, Suh PG

  • KMID: 1056227
  • Exp Mol Med.
  • 2005 Jun;37(3):161-168.
Phospholipase C-gamma1, containing two SH2 and one SH3 domains which participate in the interaction between signaling molecules, plays a significant role in the growth factor-induced signal transduction. However, the role...
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Flow Shear Stress Enhances the Proliferative Potential of Cultured Radial Glial Cells Possibly Via an Activation of Mechanosensitive Calcium Channel

Park MG, Jang H, Lee SH, Lee CJ

Radial glial cells (RGCs) which function as neural stem cells are known to be non-excitable and their proliferation depends on the intracellular calcium (Ca²⁺) level. It has been well established...
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A novel mechanism of bitter taste transduction

Kaneko A, Takeuchi H, Kurahashi , Tsunenari

  • KMID: 2071546
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):455-459.
Bitter taste is an important warning sign for animals that food is poisonous. The transduction mechanism of bitter taste is still a contradictory matter among researchers. The major current hypothesis,...
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Localization of Phosphoinositide Specific Phospholipase Cbeta Isozymes in Rat Cochlea

Park C, Han SH, Suh HK, Jung HH, Hwang SJ, Jung K, Lim HH

  • KMID: 2074345
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Feb;42(2):145-151.
BACKGROUND AND OBJECTIVES: Phosphoinositide specific phospholipase C (PLC) plays a pivotal role in the transmembrane signal transduction pathways by catalyzing the hydrolysis of phosphoinositide 4,5-bisphosphate (PIP2) to yield the intracellular...
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Distinct Cellular Calcium Metabolism in Radiation-sensitive RKO Human Colorectal Cancer Cells

Kim YT, Jo SS, Park YJ, Lee MZ, Suh CK

Radiation therapy for variety of human solid tumors utilizes mechanism of cell death after DNA damage caused by radiation. In response to DNA damage, cytochrome c was released from mitochondria...
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The Effect Erythrocyte lysate on Intracellular Calcium Concentration and the Potassium Channel in Cerebral Vasular Smooth Muscle Cells

Kim CJ

  • KMID: 2010253
  • J Korean Neurosurg Soc.
  • 1997 Dec;26(12):1644-1652.
Erythrocyte lysate increases intracellular Ca2+[Ca2+]i, causes contraction in cerebral arteries, and is thought to be the causative agent in cerebral vasospasm ; the mechanism of erythrocyte lysate-induced [Ca2+]i...
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Hydrogen peroxide inhibits Ca²⁺ efflux through plasma membrane Ca²⁺-ATPase in mouse parotid acinar cells

Kim MJ, Choi KJ, Yoon MN, Oh SH, Kim DK, Kim SH, Park HS

Intracellular Ca²⁺ mobilization is closely linked with the initiation of salivary secretion in parotid acinar cells. Reactive oxygen species (ROS) are known to be related to a variety of oxidative...
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Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration

Ok SH, Bae SI, Shim HS, Sohn JT

BACKGROUND: Dexmedetomidine is a highly selective alpha2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction...
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