- CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells
-
Lee EJ, Lee HG, Park SH, Choi EY, Park SH
- KMID: 1093617
- Exp Mol Med.
- 2003 Oct;35(5):438-447.
CD99 is a 32-kDa cell surface molecule present on thymocytes, peripheral T cells, many other hematopoietic stem cells and somatic cells were implicated in cell-cell adhesion and cell-activation phenomena. Two... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells
-
Park DS, Park JS, Yeon DS
- KMID: 711537
- Yonsei Med J.
- 1998 Apr;39(2):130-140.
- doi: 10.3349/ymj.1998.39.2.130
Many extracellular matrix molecules are expressed in the embryonic nervous system and there is some evidence that they are important regulators of neural development. Of these molecules, laminin appears to... -
- CITED
-
- Close
- SHARE
-
- Close
- Autocrine Extracellular Signal-regulated Kinase Activation in Normal Human Keratinocytes is not Interrupted by Calcium Triggering and is Involved in the Control of Cell Cycle at the Early Stage of Calciuminduced Differentiation
-
Park GT, Kim HY, Kim EK, Yang JM
- KMID: 1713190
- J Korean Med Sci.
- 2007 Apr;22(2):290-297.
- doi: 10.3346/jkms.2007.22.2.290
Normal human epidermal keratinocytes (NHEK) respond to the autocrine activated extracellular signal-regulated kinase (ERK) signaling pathway, which contributes to the survival of keratinocytes. However, during the condition of calcium-induced differentiation,... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of suramin on differentiation of human stomach cancer cell lines
-
Choe G, Kim WH, Park JG, Kim YI
- KMID: 1081036
- J Korean Med Sci.
- 1997 Oct;12(5):433-442.
- doi: 10.3346/jkms.1997.12.5.433
This study was designed to demonstrate that differentiation of stomach cancer cells can be modified by microenvironmental change and to look for a method inducing or promoting tumor cell... -
- CITED
-
- Close
- SHARE
-
- Close
- Leukotriene B4 pathway regulates the fate of the hematopoietic stem cells
-
Chung JW, Kim GY, Mun YC, Ahn JY, Seong CM, Kim JH
- KMID: 1033100
- Exp Mol Med.
- 2005 Feb;37(1):45-50.
Leukotriene B4(LTB4), derived from arachidonic acid, is a potent chemotactic agent and activating factor for hematopoietic cells. In addition to host defense in vivo, several eicosanoids have been reported to... -
- CITED
-
- Close
- SHARE
-
- Close
- Topical Prostaglandin Analogue Drugs Inhibit Adipocyte Differentiation
-
Kim JW
- KMID: 2133325
- Korean J Ophthalmol.
- 2014 Jun;28(3):257-264.
- doi: 10.3341/kjo.2014.28.3.257
PURPOSE: To investigate the effects of topical prostaglandin analogue drugs on the differentiation of adipocytes. METHODS: Differentiation of 3T3-L1 preadipocytes was induced with isobutylmethylxanthine, dexamethasone, and insulin. 3T3-L1 cells were exposed... -
- CITED
-
- Close
- SHARE
-
- Close
- Bone Morphogenetic Protein Receptor in the Osteogenic Differentiation of Rat Bone Marrow Stromal Cells
-
Wang A, Ding X, Sheng S, Yao Z
- KMID: 1071427
- Yonsei Med J.
- 2010 Sep;51(5):740-745.
- doi: 10.3349/ymj.2010.51.5.740
PURPOSE: Several signaling pathways have been shown to regulate the lineage commitment and terminal differentiation of bone marrow stromal cells (BMSCs). Bone morphogenetic protein (BMP) signaling has important effects on... -
- CITED
-
- Close
- SHARE
-
- Close
- Interaction of TGF-beta1 and rhBMP-2 on Human Bone Marrow Stromal Cells Cultured in Collagen Gel Matrix
-
Kim MK, Niyibizi C
- KMID: 720631
- Yonsei Med J.
- 2001 Jun;42(3):338-344.
- doi: 10.3349/ymj.2001.42.3.338
Transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-2 (BMP-2) are abundant proteins in the bone matrix. However, their interaction in controlling osteoblast differentiation is not clearly understood. In this study,... -
- CITED
-
- Close
- SHARE
-
- Close
- Cardiac side population cells exhibit endothelial differentiation potential
-
Yoon J, Choi SC, Park CY, Shim WJ, Lim DS
- KMID: 1090968
- Exp Mol Med.
- 2007 Oct;39(5):653-662.
Recent studies have shown that side population (SP) cells, isolated from adult myocardium, represent a distinct cardiac progenitor cell population that exhibits functional cardiomyogenic differentiation. However, information on the intrinsic... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of the Ca2+ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
-
Fu Y, Gu J, Wang Y, Yuan Y, Liu X, Bian J, Liu ZP
- KMID: 2164523
- J Vet Sci.
- 2015 Jun;16(2):151-156.
- doi: 10.4142/jvs.2015.16.2.151
The purpose of this study was to determine whether the Ca2+ signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of mouse brown adipocyte differentiation by second-generation antipsychotics
-
Oh JE, Cho YM, Kwak SN, Kim JH, Lee KW, Jung H, Jeong SW, Kwon OJ
- KMID: 1389734
- Exp Mol Med.
- 2012 Sep;44(9):545-553.
Brown adipose tissue is specialized to burn lipids for thermogenesis and energy expenditure. Second-generation antipsychotics (SGA) are the most commonly used drugs for schizophrenia with several advantages over first-line drugs,... -
- CITED
-
- Close
- SHARE
-
- Close
- Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1beta-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1
-
Lee EG, Yun HJ, Lee SI, Yoo WH
- KMID: 1785661
- Korean J Intern Med.
- 2010 Mar;25(1):93-100.
- doi: 10.3904/kjim.2010.25.1.93
BACKGROUND/AIMS: The present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1beta-stimulated receptor activator of NF-kappaB ligand (RANKL)-mediated osteoclast differentiation.... -
- CITED
-
- Close
- SHARE
-
- Close
- Duration and Magnitude of Extracellular Signal-Regulated Protein Kinase Phosphorylation Determine Adipogenesis or Osteogenesis in Human Bone Marrow-Derived Stem Cells
-
Jung HS, Kim YH, Lee JW
- KMID: 1106452
- Yonsei Med J.
- 2011 Jan;52(1):165-172.
- doi: 10.3349/ymj.2011.52.1.165
PURPOSE: Imbalances between osteogenic and adipogenic differentiation leads to diseases such as osteoporosis. The aim of our study was to demonstrate the differences in extracellular signal-regulated kinase (ERK) phosphorylation during... -
- CITED
-
- Close
- SHARE
-
- Close
- The biologic role of ganglioside in neuronal differentiation: effects of GM1 ganglioside on human neuroblastoma SH-SY5Y cells
-
Lee MC, Lee WS, Park CS, Juhng SW
- KMID: 1422174
- J Korean Med Sci.
- 1994 Apr;9(2):179-187.
- doi: 10.3346/jkms.1994.9.2.179
Human neuroblastoma SH-SY5Y cell is a cloned cell line which has many attractive features for the study of neuronal proliferation and neurite outgrowth, because it has receptors for insulin, IGF-I... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of pharmacological and genetic inhibition of cyclooxygenase-2: effects on adult neurogenesis in the hippocampal dentate gyrus
-
Nam SM, Kim JW, Yoo DY, Choi JH, Kim W, Jung HY, Won MH, Hwang IK, Seong JK, Yoon YS
- KMID: 2344296
- J Vet Sci.
- 2015 Sep;16(3):245-251.
- doi: 10.4142/jvs.2015.16.3.245
Inducible cyclooxygenase-2 (COX-2) has received much attention because of its role in neuro-inflammation and synaptic plasticity. Even though COX-2 levels are high in healthy animals, the function of this factor... -
- CITED
-
- Close
- SHARE
-
- Close
- Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones
-
Woo KM, Choi Y, Ko SH, Ko JS, Oh KO, Kim KK
- KMID: 755206
- Exp Mol Med.
- 2002 Nov;34(5):347-352.
Osteoprotegerin (OPG), a member of the tumor necrosis factor receptor superfamily, is known to inhibit osteoclastogenesis by acting as a soluble decoy receptor for the receptor activator of NF-kB ligand... -
- CITED
-
- Close
- SHARE
-
- Close
- 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells
-
Choi SC, Yoon JH, Shim WJ, Ro YM, Lim DS
- KMID: 1103318
- Exp Mol Med.
- 2004 Dec;36(6):515-523.
The P19 embryonal carcinoma cell line is a useful model cells for studies on cardiac differentiation. However, its low efficacy of differentiation hampers its usefulness. We investigated the effect of... -
- CITED
-
- Close
- SHARE
-
- Close
- TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells
-
Lee JH, Park BJ, Park JH, Yang MH, Chi SG
- KMID: 755040
- Exp Mol Med.
- 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in... -
- CITED
-
- Close
- SHARE
-
- Close
- Fucoidan promotes osteoblast differentiation via JNK- and ERK-dependent BMP2-Smad 1/5/8 signaling in human mesenchymal stem cells
-
Kim BS, Kang HJ, Park JY, Lee J
- KMID: 2155393
- Exp Mol Med.
- 2015 Jan;47(1):e128.
- doi: 10.1038/emm.2014.95
Fucoidan has attracted attention as a potential drug because of its biological activities, which include osteogenesis. However, the molecular mechanisms involved in the osteogenic activity of fucoidan in human alveolar... -
- CITED
-
- Close
- SHARE
-
- Close
- Reduction of adult hippocampal neurogenesis is amplified by aluminum exposure in a model of type 2 diabetes
-
Nam SM, Kim JW, Yoo DY, Jung HY, Choi JH, Hwang IK, Seong JK, Yoon YS
- KMID: 2363330
- J Vet Sci.
- 2016 Mar;17(1):13-20.
- doi: 10.4142/jvs.2016.17.1.13
In this study, we investigated the effects of chronic aluminum (Al) exposure for 10 weeks on cell proliferation and neuroblast differentiation in the hippocampus of type 2 diabetic rats. Six-week-old... -
- CITED
-
- Close
- SHARE
-
- Close
