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A Case of Scabies Incognito

Yi JY, Park CW, Cho BK, Houh W

  • KMID: 1679596
  • Korean J Dermatol.
  • 1986 Aug;24(4):518-522.
Numerous burrows developed in a 20-year-old male student who had been terated with topical fluorinated corticosteroid for 2 months. The number of burrows is the largest on scrotum(15/cm) and then...
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A Study for Skin Protection Effect of Sunscreens: I . Comparison of Effectiveness by the Concentration

Lee AY, Youn JI, Lee YS

  • KMID: 2146651
  • Korean J Dermatol.
  • 1984 Jun;22(3):295-301.
The purpose of this study is to evaluate the effectiveness of these para-amino- benzoate, benzophenone and cinnamate sunscreens in the same base(cream) and the effect of concentration on sun protection...
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A Case of Human Infestation of Canine Scabies

Kang SB, Lee JY, Cho BK, Houh W

  • KMID: 2038971
  • Korean J Dermatol.
  • 1988 Aug;26(4):570-574.
We present herein a case of human infestation of canine scabies occuring in a 7l-year-old female patient. Severe pruritic, erythematous papular lesions and excoriation were found over the abdomen, submammary...
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Acute Tubulointerstitial Nephritis Induced by Deferasirox following Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Min JW, Hwang SJ, Lim YJ, Lee YH

Deferasirox is a once-daily, oral iron-chelating agent that is now widely available for the treatment of transfusional hemosiderosis. Deferasirox represents a significant advance in the treatment of iron overload, as...
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A Clinical and Histopathological Study of Experimental Canine Scabies

Hong JK, Jang IG, Cho BK, Lee WK

BACKGROUND: Canine scabies is caused by an infestation of Sarcoptes scabiei var. canis (S. canis) in dogs and they can be transmitted to humans. Recently pet raising has been increasing...
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Qualitative Alteration in Hepatic Microsomal Cytochrome P-450 Apoproteins Associated with Bile Duct Ligation, and the Administration of Cholic Acid and Phenobarbital

Sung NE, Kim BH, Hong YS, Choi KJ

We have investigated in rat liver whether different forms of cytochrome P-450 are alterated in hepatic disorders associated with impaired drug metabolism. Total hepatic cytochrome P-450 is decreased after either...
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Effects of oral iron chelator deferasirox on human malignant lymphoma cells

Choi JG, Kim JL, Park J, Lee S, Park SJ, Kim JS, Choi CW

BACKGROUND: Iron is essential for cell proliferation and viability. It has been reported that iron depletion by a chelator inhibits proliferation of some cancer cells. Deferasirox is a new oral...
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The Usefulness of the Computed Tomography for Diagnosing DeepVenous Thrombosis of the Lower Extremities

Yi JH, Park SJ, Kwon EK, Oh YJ, Kang TW, Hwang JC, Kang BS, Choi SH, Cho HR

  • KMID: 2096863
  • J Korean Soc Vasc Surg.
  • 2009 May;25(1):12-16.
PURPOSE: This study aims to access the usefulness of indirect computed tomographic venography (CTV) after performing computed tomographic pulmonary angiography (CTPA) to detect deep venous thrombosis. METHODS: Eighty six patients who...
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Roles of Metabotropic Glutamate Receptors 1 and 5 in Rat Medial Vestibular Nucleus Neurons

Lee HI, Lee SH, Chun SW

  • KMID: 2170733
  • Int J Oral Biol.
  • 2011 Jun;36(2):71-78.
Using whole cell current- and voltage-clamp recording we investigated the characteristics and pharmacology of group I metabotropic glutamate receptor (mGluR)-mediated responses in rat medial vestibular nucleus (MVN) neurons. In current...
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Effects of Angiotensin II and Shear Stress Interaction on Vascular Inflammation

Choi SH, Park EH, Oh Y, Baek SH

BACKGROUND: Angiotensin II (AngII) and abnormal oscillatory shear stress are highly associated with vascular inflammation including atherosclerosis. However, it is poorly understood how interactions between AngII and shear stress in...
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Nitric Oxide Modulation of GABAergic Synaptic Transmission in Mechanically Isolated Rat Auditory Cortical Neurons

Lee JJ

The auditory cortex (A1) encodes the acquired significance of sound for the perception and interpretation of sound. Nitric oxide (NO) is a gas molecule with free radical properties that functions...
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Economic Evaluation of Iron Chelation Agents: Oral Deferasirox versus Infusional Deferoxamine

Kim JH, Kim YH

BACKGROUND: Patients with transfusional iron overload have relied on treatment with deferoxamine, a standard chelating agent. Deferoxamine is administered by intravenous or subcutaneous infusion over an 8~12 hour period 5~7...
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Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

Jin Y, Kim J, Kwak J

Recent studies have demonstrated that nitric oxide (NO) activates transient receptor potential vanilloid subtype 1 (TRPV1) via S-nitrosylation of the channel protein. NO also modulates various cellular functions via activation...
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Effects of estrogen on food intake, serum leptin levels and leptin mRNA expression in adipose tissue of female rats

Fungfuang , Terada M, Komatsu N, Moon C, Saito TR

  • KMID: 2312110
  • Lab Anim Res.
  • 2013 Sep;29(3):168-173.
The integration of metabolism and reproduction involves complex interactions of hypothalamic neuropeptides with metabolic hormones, fuels, and sex steroids. Of these, estrogen influences food intake, body weight, and the accumulation...
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Comparison of Immune Responses Induced by Deferoxamine and Deferasirox

Jung YS, Bae EY, Chung NG, Cho B, Kim HK, Min CK, Han CW, Kim HS, Jeong DC

BACKGROUND: The iron chelating agents (ICA) have various biological effects besides iron chelation. We investigated the immunomodulatory effects of Deferasirox (DFS) compared to Deferoxamine (DFO). METHODS: Spleen cells (SP) were obtained...
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The Effects of Antihypertensive Drugs on Bone Mineral Density in Ovariectomized Mice

Kang KY, Kang Y, Kim M, Kim Y, Yi H, Kim J, Jung HR, Park SH, Kim HY, Ju JH, Hong YS

The effects of several antihypertensive drugs on bone mineral density (BMD) and micro-architectural changes in ovariectomized (OVX) mice were investigated. Eight-week-old female C57/BL6 mice were used for this study. Three...
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Korean Guideline for Iron Chelation Therapy in Transfusion-Induced Iron Overload

Jang JH, Lee JH, Yoon SS, Jo DY, Kim HJ, Chung J, Lee JW

Many Korean patients with transfusion-induced iron overload experience serious clinical sequelae, including organ damage, and require lifelong chelation therapy. However, due to a lack of compliance and/or unavailability of an...
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Purification and Characterization of Guanine Aminohydrolase from Rat Cerebrum

Cha HJ, Jung HW, Koh YC, Sim BS, Park JB, Kim SW

  • KMID: 1953539
  • J Korean Neurosurg Soc.
  • 1984 Dec;13(4):611-625.
Guanine aminohydrolase(GAH;EC 3. 5. 4. 3.) was partially purified 122-fold from rat cerebrum to a specific activity of 7.22 in its per mg protein with a recovery of 7.47% by...
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Effects of Ovariectomy and Estrogen Replacement on Rat Bladder Physiology and Morphology

Lim JS, Gil G, Shin JH, Kim KS, Koo DY, Kim JK, Sul CK, Na YG

  • KMID: 2330625
  • J Korean Continence Soc.
  • 2007 Dec;11(2):177-188.
PURPOSES: An overactive bladder is highly prevalent in middle-aged woman, especially during the postmenopausal period. We evaluated the relationship between detrusor overactivity and postmenopausal state and the effects of estrogen...
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Telmisartan Versus Valsartan in Patients With Hypertension: Effects on Cardiovascular, Metabolic, and Inflammatory Parameters

Lim SY, Kim SW, Kim EJ, Kang JH, Kim SA, Kim YK, Na JO, Choi CU, Lim HE, Han SW, Rha SW, Park CG, Seo HS, Oh DJ

BACKGROUND AND OBJECTIVES: Angiotensin-receptor blockers (ARBs) have beneficial effects on cardiovascular, metabolic, and inflammatory parameters in addition to controlling blood pressure (BP). However, few comparative clinical studies have been conducted...
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