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Importance of the Molecular Epidemiological Monitoring of Carbapenem-Resistant Pseudomonas aeruginosa

Kim YA

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Application of Optical Genome Mapping to the Genetic Diagnosis of Facioscapulohumeral Muscular Dystrophy 1

Lee ST

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Association Between Plasma Anti-Factor Xa Concentrations and Large Artery Occlusion in Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants for Non-valvular Atrial Fibrillation

Kim DH, Kwak BC, Yoon BA, Cha JK, Park JS, Kwak MS, Woo KS, Han JY

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Comparison of Target- and IgG-Enrichment Strategies to Measure Adalimumab Concentrations in Human Plasma Using an Immunocapture-Liquid Chromatography-High-Resolution Mass Spectrometry Platform

Ding X, Zhu S, Liu L, Liu X, Zhu K, Miao L

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Next-Generation Patient-Based Real-Time Quality Control Models

Duan X, Zhang M, Liu Y, Zheng W, Lim CY, Kim S, Loh TP, Guo W, Zhou R, Badrick T, On behalf of the Patient-Based Real-Time Quality Control Working Group of the Asia Pacific Federation of Clinical Biochemistry and Laboratory Medicine

Patient-based real-time QC (PBRTQC) uses patient-derived data to assess assay performance. PBRTQC algorithms have advanced in parallel with developments in computer science and the increased availability of more powerful computers....
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Multiple Primary Cancers With Hematologic Malignancies and Germline Predisposition: A Case Series

Yun J, Lee DS, Lee S, Yun H

The term “multiple primary (MP) cancers” refers to the existence of more than one cancer in the same patient. The combination of MP cancers with hematological malignancies is relatively uncommon....
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Educational Outcomes and Perception Changes in Medical Students After Visiting a Blood Donation Center

Lee J, Kim S, Jeong SY, Yoon SY, Lee N, Won JH, Shin JW, Kwon SH, Lee MY, Kim KH

Educating primary care physicians about blood donation and transfusion is critical. The Division of Hematology and Oncology at Soonchunhyang University Seoul Hospital in Korea introduced an on-site educational program termed...
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Prevalence and Molecular Characterization of Vancomycin Variable Enterococcus faecium Isolated From Clinical Specimens

Yoo IY, Kwon JA, Lee M, Jung SH, Kim JO, Ha SI, Park YJ

Vancomycin variable Enterococcus (VVE) bacteria are phenotypically susceptible to vancomycin, but they harbor the vanA gene. We aimed to ascertain the prevalence of VVE among clinically isolated vancomycin-susceptible Enterococcus faecium...
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Evaluating the TaqMan Jra -Genotyping Method for Rapidly Predicting the Presence of Anti-Jra Antibodies

Koo YK, Kwon SS, Suh EJ, Kim NH, Kim HK, Cho YK, Choi SJ, Kim S, Lee KA

Background: The Jr a antigen is a high-prevalence red blood cell (RBC) antigen. Reports on cases of fatal hemolytic disease of the fetus and newborn and acute hemolytic transfusion reactions...
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Clinical Application of Optical Genome Mapping for Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy

Shim Y, Seo J, Lee ST, Choi JR, Choi YC, Shin S, Park HJ

Background: Facioscapulohumeral muscular dystrophy (FSHD) is a common form of muscular dystrophy that mainly affects skeletal muscle. FSHD1 accounts for 95% of all FSHD cases and can be diagnosed based...
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Clonal Distribution and Its Association With the Carbapenem Resistance Mechanisms of Carbapenem-Non-Susceptible Pseudomonas aeruginosa Isolates From Korean Hospitals

Kim N, Ko SY, Park SY, Kim SY, Lee DE, Kwon KT, Kim YK, Lee JC

Background: Carbapenem resistance in Pseudomonas aeruginosa is a serious global health problem. We investigated the clonal distribution and its association with the carbapenem resistance mechanisms of carbapenem-non-susceptible P. aeruginosa isolates...
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Platelet and Monocyte Microvesicles as Potential Biomarkers of COVID-19 Severity: A Cross-Sectional Analysis

Nunki N, Hernaningsih Y, Wardhani P, Herawati A, Yusoff NM, Moses EJ, Semedi BP

Background: Coronavirus disease (COVID-19) induces inflammation, coagulopathy following platelet and monocyte activation, and fibrinolysis, resulting in elevated D-dimer levels. Activated platelets and monocytes produce microvesicles (MVs). We analyzed the differences in...
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Metformin Suppresses Both PD-L1 Expression in Cancer Cells and Cancer-Induced PD-1 Expression in Immune Cells to Promote Antitumor Immunity

Park SH, Lee J, Yun HJ, Kim SH, Lee JH

Background: Metformin, a drug prescribed for patients with type 2 diabetes, has potential efficacy in enhancing antitumor immunity; however, the detailed underlying mechanisms remain to be elucidated. Therefore, we aimed...
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Association Between the Red Blood Cell Distribution Width and 30-Day Mortality in Intensive Care Patients Undergoing Cardiac Surgery: A Retrospective Observational Study Based on the Medical Information Mart for Intensive Care-IV Database

Chen W, Yu P, Chen C, Cai S, Chen J, Zheng C, Chen C, Zheng L, Guo C

Background: Millions of patients undergo cardiac surgery each year. The red blood cell distribution width (RDW) could help predict the prognosis of patients who undergo percutaneous coronary intervention or coronary...
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