- Toward Standardization of Flow-Cytometric Immunophenotyping for the Diagnosis and Monitoring of Hematologic Malignancies
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Kim SY, Huh HJ
- KMID: 2555682
- Ann Lab Med.
- 2024 May;44(3):193-194.
- doi: 10.3343/alm.2023.0467
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- Twins With an Identical Novel Mutation in ITGB3: A Case Report of Glanzmann Thrombasthenia–like Syndrome
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Lee J, Lee JM, Kim HS, Jung J, Kim Y, Park SY, Kim M, Han E
- KMID: 2555709
- Ann Lab Med.
- 2024 May;44(3):299-302.
- doi: 10.3343/alm.2023.0375
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- The First Case of Congenital Nephrogenic Diabetes Insipidus Caused by AVPR2 Disruption Because of 4q25 Insertional Translocation
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Kim B, Ahn YH, Park JH, Lim HS, Chae SW, Lee JS, Kang HG, Kim MJ, Seong MW
- KMID: 2555710
- Ann Lab Med.
- 2024 May;44(3):303-305.
- doi: 10.3343/alm.2023.0361
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- Clinical Practice Guideline for Blood-based Circulating Tumor DNA Assays
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Lee JS, Cho EH, Kim B, Hong J, Kim Yg, Kim Y, Jang JH, Lee ST, Kong SY, Lee W, Shin S, Song EY, on behalf of the Clinical Practice Guidelines Committee of the Korean Society for Laboratory Medicine
- KMID: 2555683
- Ann Lab Med.
- 2024 May;44(3):195-209.
- doi: 10.3343/alm.2023.0389
Circulating tumor DNA (ctDNA) has emerged as a promising tool for various clinical applications, including early diagnosis, therapeutic target identification, treatment response monitoring, prognosis evaluation, and minimal residual disease detection.... -
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- Performance Evaluation of the Roche Cobas 5800 HBV and HCV Tests: Comparison of the 200 and 500 μL Protocols
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Jeong S, Lee SK, Cho EJ, Kim HS, Lee YK, Kim JS, Song W, Kim HS
- KMID: 2555696
- Ann Lab Med.
- 2024 May;44(3):253-261.
- doi: 10.3343/alm.2023.0306
Background: Clinical management of patients infected with hepatitis B virus (HBV) or hepatitis C virus (HCV) relies on the viral load (VL). The Cobas 5800 system (Roche Diagnostics) can determine... -
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- Evaluation of Coefficients of Variation for Clinical Chemistry Tests Based on Internal Quality Control Data Across 5,425 Laboratories in China From 2013 to 2022
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Wang W, Zhang Z, Zhang C, Zhao H, Yuan S, Liu J, Dong N, Wang Z, Kang F
- KMID: 2555695
- Ann Lab Med.
- 2024 May;44(3):245-252.
- doi: 10.3343/alm.2023.0236
Background: Clinical chemistry tests are most widely used in clinical laboratories, and diverse measurement systems for these analyses are available in China. We evaluated the imprecision of clinical chemistry measurement... -
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- Optimization of a Protocol for Isolating Cell-free DNA From Cerebrospinal Fluid
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Song HH, Park H, Cho D, Bang HI, Oh HJ, Kim J
- KMID: 2555708
- Ann Lab Med.
- 2024 May;44(3):294-298.
- doi: 10.3343/alm.2023.0267
A standardized protocol for the isolation of cell-free DNA (cfDNA) from cerebrospinal fluid (CSF) is lacking. Therefore, we established a cfDNA isolation protocol optimized for clinical CSF specimens, integrating acceptable... -
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- Optimizing the Hospital Blood Bank Stock in Korea: A Comparative Analysis of the Uniform 5-Day Stock Index and a Novel Blood Stock Index
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Park SJ, Lim YA, Kim KH
- KMID: 2555697
- Ann Lab Med.
- 2024 May;44(3):262-270.
- doi: 10.3343/alm.2023.0242
Background: Maintaining optimal blood inventory levels in hospitals is important to prevent blood shortage and wastage. We aimed to provide an efficient blood inventory management strategy for hospital blood banks... -
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- Primary Hyperoxaluria Screening and Monitoring: Quantitative Measurement of Plasma Oxalate by Gas Chromatography-Mass Spectrometry With High Sensitivity
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Yazdanpanah M, Cameron J, Chappel C, Yuan L
- KMID: 2555694
- Ann Lab Med.
- 2024 May;44(3):235-244.
- doi: 10.3343/alm.2023.0178
Background: Plasma oxalate measurements can be used for the screening and therapeutic monitoring of primary hyperoxaluria. We developed a gas chromatography-mass spectrometry (GC-MS) assay for plasma oxalate measurements with high... -
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- Re-evaluation of a Fibrillin-1 Gene Variant of Uncertain Significance Using the ClinGen Guidelines
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Kim SW, Kim B, Kim Y, Lee KA
- KMID: 2555698
- Ann Lab Med.
- 2024 May;44(3):271-278.
- doi: 10.3343/alm.2023.0152
Background: Marfan syndrome (MFS) is caused by fibrillin-1 gene (FBN1) variants. Mutational hotspots and/or well-established critical functional domains of FBN1 include cysteine residues, calcium-binding consensus sequences, and amino acids related... -
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- Current Challenges in Chimeric Antigen Receptor T-cell Therapy in Patients With B-cell Lymphoid Malignancies
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Kim SJ, Yoon SE, Kim WS
- KMID: 2555684
- Ann Lab Med.
- 2024 May;44(3):210-221.
- doi: 10.3343/alm.2023.0388
Chimeric antigen receptor (CAR) T-cell therapy is a promising immunotherapy based on genetically engineered T cells derived from patients. The introduction of CAR T-cell therapy has changed the treatment paradigm... -
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- Association Between Aortic Valve Sclerosis and Clonal Hematopoiesis of Indeterminate Potential
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Kim M, Kim JJ, Lee ST, Shim Y, Lee H, Bae S, Son NH, Shin S, Jung IH
- KMID: 2555706
- Ann Lab Med.
- 2024 May;44(3):279-288.
- doi: 10.3343/alm.2023.0268
Background: The mechanism and medical treatment target for degenerative aortic valve disease, including aortic stenosis, is not well studied. In this study, we investigated the effect of clonal hematopoiesis of... -
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- Neutralization Testing–based Immunogenicity Analysis of Recent Prevalent Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Sublineages
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Lee EJ, Lee H, O SW, Rhee JE, Kim JM, Kim DJ, Kim IH, No JS, Park AK, Kim JA, Lee CY, Choi YK, Kim EJ
- KMID: 2555707
- Ann Lab Med.
- 2024 May;44(3):289-293.
- doi: 10.3343/alm.2023.0256
Although WHO declared the end of the public health emergency for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), XBB lineages continue to evolve and... -
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- Current Status of Flow Cytometric Immunophenotyping of Hematolymphoid Neoplasms in Korea
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Park M, Lim J, Ahn A, Oh EJ, Song J, Kim KH, Han JY, Choi HW, Park JH, Shin KH, Kim H, Kim M, Hwang SH, Kim HY, Cho D, Kang ES
- KMID: 2555685
- Ann Lab Med.
- 2024 May;44(3):222-234.
- doi: 10.3343/alm.2023.0298
Background: Flow cytometric immunophenotyping of hematolymphoid neoplasms (FCIHLN) is essential for diagnosis, classification, and minimal residual disease (MRD) monitoring. FCI-HLN is typically performed using in-house protocols, raising the need for... -
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