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Laboratory Data Quality Evaluation in the Big Data Era

Kim S

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RHD*DNT (RHD*38) Showing D-Positive Reactivity on Rhesus D Typing and Forming Anti-D Antibody

Lee GH, Kim H, Hur M, So KA, Shin DW, Hong YJ, Park KU

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The Issue With Osmotic Shock Hemolysate Preparation Procedure

Kalaria T

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The First Case of Catheter-related Bloodstream Infection Caused by Kocuria rhizophila in Korea

Kim Y, Kim TS, Park H, Yun KW, Park JH

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Real-World Evidence of Point-of-Care Glucometers: Enhanced Passive Surveillance and Adverse Event Reporting Status in Korea and the United States

Choi S, Choi SJ, Kim JK, Lee YW, Lee YK

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Artificial Intelligence in Point-of-Care Testing

Khan AI, Khan M, Khan R

With the projected increase in the global population, current healthcare delivery models will face severe challenges. Rural and remote areas, whether in developed or developing countries, are characterized by the...
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Status of Pre-analytical Quality Management of Laboratory Tests at Primary Clinics in Korea

Chang J, Lim J, Chung JW, Sohn YH, Jang MJ, Kim S

Background: The quality of laboratory test results is crucial for accurate clinical diagnosis and treatment. Pre-analytical errors account for approximately 60%–70% of all laboratory test errors. Laboratory test results may...
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Functional Reference Limits: Describing Physiological Relationships and Determination of Physiological Limits for Enhanced Interpretation of Laboratory Results

Chuah TY, Lim CY, Tan RZ, Pratumvinit B, Loh TP, Vasikaran S, Markus C, for the APFCB Harmonization of Reference Intervals Working Group

Functional reference limits describe key changes in the physiological relationship between a pair of physiologically related components. Statistically, this can be represented by a significant change in the curvature of...
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A New Strategy for Evaluating the Quality of Laboratory Results for Big Data Research: Using External Quality Assessment Survey Data (2010–2020)

Cho EJ, Jeong TD, Kim S, Park HD, Yun YM, Chun S, Min WK

Background: To ensure valid results of big data research in the medical field, the input laboratory results need to be of high quality. We aimed to establish a strategy for...
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Clinical Significance of Serum IgG4 in the Diagnosis and Treatment Response of IgG4-Related Disease in Adults of Southwest China: A Retrospective Study

Wei B, Guo Y, Ou X, Lin L, Su Z, Li L, Wu X, Cai B

Background: There is no standard cut-off value of serum IgG4 concentration and serum IgG4/total IgG ratio for the diagnosis of IgG4-related disease (IgG4-RD) or as a marker of treatment responses....
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Effective and Practical Complete Blood Count Delta Check Method and Criteria for the Quality Control of Automated Hematology Analyzers

Kim MS, Park CJ, Namgoong S, Kim SI, Cho YU, Jang S

Background: Delta checks increase patient safety by identifying automated hematology analyzer errors. International standards and guidelines for the complete blood count (CBC) delta check method have not been established. We...
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Pre-transfusion Testing Using Crossmatching Agglutination Reaction Grades Combined With Rh Subgroup Phenotyping in Patients With Autoantibodies: A Three-year Experience at a Tertiary Hospital

Kim J, Shin KH, Kim H, Kim HH, Lee HJ

Background: The currently recommended pre-transfusion testing techniques for patients with autoantibodies are complex, time-consuming, and labor-intensive. Therefore, although the red blood cell (RBC) selection method using crossmatched RBC agglutination reaction...
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European Committee on Antimicrobial Susceptibility Testing-Recommended Rapid Antimicrobial Susceptibility Testing of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus From Positive Blood Culture Bottles

Park JM, Kwon M, Hong KH, Lee H, Yong D

Background: Early diagnosis and treatment are important for a good prognosis of bloodstream infections. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommends rapid antimicrobial susceptibility testing (RAST) based on...
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Reducing Microbial Contamination in Hematopoietic Stem Cell Products and Quality Improvement Strategy: Retrospective Analysis of 1996-2021 Data

Ko YK, Lee JK, Park HK, Han AK, Mun SK, Park HJ, Choung HK, Kim SM, Choi KM, Lee NY, Cho D, Kim DW, Kang ES

Background: Sterility and safety assurance of hematopoietic stem cell (HSC) products is critical in transplantation. Microbial contamination can lead to product disposal and increases the risk of unsuccessful clinical outcomes....
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Implications of the 5th Edition of the World Health Organization Classification and International Consensus Classification of Myeloid Neoplasm in Myelodysplastic Syndrome With Excess Blasts and Acute Myeloid Leukemia

Lee C, Kim HN, Kwon JA, Yoon SY, Jeon MJ, Yu ES, Kim DS, Choi CW, Yoon J

The fifth edition of the WHO classification (2022 WHO) and the International Consensus Classification (2022 ICC) of myeloid neoplasms have been recently published. We reviewed the changes in the diagnosis...
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Comparison of Nasal Swabs, Nasopharyngeal Swabs, and Saliva Samples for the Detection of SARS-CoV-2 and other Respiratory Virus Infections

Jung EJ, Lee SK, Shin SH, Kim JS, Woo H, Cho EJ, Hyun J, Kim JS, Kim HS

Background: Nasal swabs and saliva samples are being considered alternatives to nasopharyngeal swabs (NPSs) for detecting severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2); however, few studies have compared the usefulness of...
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Evaluation of the AdvanSure One-Stop COVID-19 Plus Kit for SARS-CoV-2 Detection Using a Streamlined RNA Extraction Method

Kim TY, Shim HJ, Jeong E, Kang M, Jang JH, Huh HJ, Lee NY

Real-time reverse transcription (rRT)-PCR, which is the reference standard for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, generally involves a time-consuming and costly RNA extraction step...
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Performance Validation of Three Scoring Systems for the Prediction of Thrombotic Microangiopathy Due to Severe ADAMTS13 Deficiency and the Response to Therapeutic Plasma Exchange: First Study in Korea

Park SH, Kim HK, Jeong J, Lee SH, Lee YJ, Kim YJ, Jo JC, Lim JH

Background: The BENTLEY score (B-S), French thrombotic microangiopathy (TMA) Reference Center score (FTMA-S), and PLASMIC score (PLASMIC-S) have been developed for TMA diagnostic prediction. We retrospectively validated their predictive performances...
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Effect of Lymphocyte Phenotypic Alterations on the Humoral Response to Vaccination Against SARS-COV-2 in Dialysis Patients

Lioulios G, Fylaktou A, Asouchidou D, Xochelli A, Nikolaidou V, Stai S, Christodoulou M, Giamalis P, Tsouchnikas I, Papagianni A, Stangou M

Background: The response to vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) varies depending on comorbidities. This study evaluated the clinical and immunological factors affecting the humoral response of...
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