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Optical coherence tomography angiography in preclinical neuroimaging

Choi WJ

Preclinical neuroimaging allows for the assessment of brain anatomy, connectivity, and function in laboratory animals, such as mice and this imaging field has been a rapidly growing aimed at bridging...
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Welcome to Laboratory Animal Research

Seong JK

No abstract available.
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Machine-Learning Based Automatic and Real-time Detection of Mouse Scratching Behaviors

Park I, Lee K, Bishayee K, Jeon HJ, Lee H, Lee U

Scratching is a main behavioral response accompanied by acute and chronic itch conditions, and has been quantified as an objective correlate to assess itch in studies using laboratory animals. Scratching...
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The Formation of the Military Medical System of the Korean People's Army and the Military Medical Officer

KIM S

The military medical system of the Korean People's Army (KPA) first appeared in August 1946 when a central military hospita was established at the headquarters. Inside the KPA, the military...
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ELISA for Quantitative Determination of Hepatitis B Virus Surface Antigen

Kim SH

Several studies have reported a good correlation between levels of serum hepatitis B virus surface antigen (HBsAg) and covalently closed circular DNA (cccDNA) before and after antiviral therapy. As a...
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Use of C57BL/6N mice on the variety of immunological researches

Song HK, Hwang DY

Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new...
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Comparison of commonly used ICR stocks and the characterization of Korl:ICR

Shin HJ, Cho YM, Shin HJ, Kim HD, Choi KM, Kim MG, Shin HD, Chung MW

Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology,...
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Regeneration of Bovine Mammary Gland in Immunodeficient Mice by Transplantation of Bovine Mammary Epithelial Cells Mixed with Matrigel

Park HJ, Lee WY, Jeong HY, Song H

BACKGROUND AND OBJECTIVES: With the global demand for dairy protein for consumption growing annually, there has been increasing activity in the research field of dairy protein synthesis and production. From...
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Detection of Helicobacter felis in a cat with gastric disease in laboratory animal facility

Hong S, Chung Y, Kang WG, Kim O

A 3-month-old male cat in the animal facility was presented for investigation of anorexia and occasional vomiting. We collected the specimens from gastroscopic biopsy and stool collection. The gastroscopic biopsy...
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Engineering therapeutic antibodies targeting G-protein–coupled receptors

Jo M, Jung ST

G-protein–coupled receptors (GPCRs) are one of the most attractive therapeutic target classes because of their critical roles in intracellular signaling and their clinical relevance to a variety of diseases, including...
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Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey

An H, Cho DW, Lee SE, Yang YS, Han SC, Lee CJ

Many researchers are using viruses to deliver genes of interest into the brains of laboratory animals. However, certain target brain cells are not easily infected by viruses. Moreover, the differential...
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Comparison of three diagnostic assays for the identification of Helicobacter spp. in laboratory dogs

Hong S, Chung Y, Kang WG, Choi YS, Kim O

A number of Helicobacter species may confound experimental data because of their association with disease progressing in various kinds of laboratory animals. Screening of Helicobacter species is particularly desirable, because...
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Oxidative DNA Damage from Nanoparticle Exposure and Its Application to Workers' Health: A Literature Review

Rim KT, Song SW, Kim HY

  • KMID: 2317101
  • Saf Health Work.
  • 2013 Dec;4(4):177-186.
The use of nanoparticles (NPs) in industry is increasing, bringing with it a number of adverse health effects on workers. Like other chemical carcinogens, NPs can cause cancer via oxidative...
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Susceptibility of Laboratory Rodents to Trichinella papuae

Sadaow L, Intapan PM, Boonmars T, Morakote N, Maleewong

Members of the genus Trichinella are small nematodes that can infect a wide range of animal hosts. However, their infectivity varies depending on the parasite and host species combination. In...
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Development of Artificial Pulmonary Nodule for Evaluation of Motion on Diagnostic Imaging and Radiotherapy

Woo SK, Park NW, Park SW, Yu JW, Han SC, Lee SJ, Kim KM, Kang JH, Ji YH, Eom KD

  • KMID: 2315748
  • Prog Med Phys.
  • 2013 Mar;24(1):76-83.
Previous studies about effect of respiratory motion on diagnostic imaging and radiation therapy have been performed by monitoring external motions but these can not reflect internal organ motion well. The...
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Usefulness of a Helicobacter pylori stool antigen test for diagnosing H. pylori infected C57BL/6 mice

Moon DI, Shin EH, Oh HG, Oh JS, Hong S, Chung Y, Kim O

  • KMID: 2312100
  • Lab Anim Res.
  • 2013 Mar;29(1):27-32.
Among several diagnostic tests, a Helicobacter pylori stool antigen (HpSA) test may offer a useful noninvasive method for diagnosing infection without sacrificing animals. In this study, male C57BL/6 mice (n=6)...
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Monitoring of antibiotic resistance in bacteria isolated from laboratory animals

Goo JS, Jang MK, Shim SB, Jee SW, Lee SH, Bae CJ, Park S, Kim KJ, Kim JE, Hwang IS, Lee HR, Choi SI, Lee YJ, Lim CJ, Hwang DY

The drug resistance of microorganisms isolated from laboratory animals never treated with antibiotics is being reported consistently, while the number of laboratory animals used in medicine, pharmacy, veterinary medicine, agriculture,...
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Molecular identification of Mycoplasma cynos from laboratory beagle dogs with respiratory disease

Hong S, Kim O

  • KMID: 2312094
  • Lab Anim Res.
  • 2012 Mar;28(1):61-66.
In this study, we examined a colony of 20 beagle dogs in a laboratory animal facility. Mycoplasma was detected by consensus PCR assay in 1 dog with respiratory and constitutional...
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Submucosal Endoscopy, a New Era of Pure Natural Orifice Translumenal Endoscopic Surgery (NOTES)

Lee SH, Cho WY, Cho JY

Natural orifice translumenal endoscopic surgery (NOTES) involves the intentional perforation of the viscera with an endoscope to access the abdominal cavity and perform an intraabdominal operation. In a brief time...
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Identification of bacteria from the oral cavity and cloaca of snakes imported from Vietnam

Jho YS, Park DH, Lee JH, Cha SY, Han JS

Reptiles are used for various purposes these days, including public exhibits, medicinal applications, and as laboratory animals. As the international exchange of reptiles has gradually increased, more people have had...
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