Ewha Med J.  1991 Mar;14(1):45-50. 10.12771/emj.1991.14.1.45.

Study on Some Aspects of Infection in Laboratory Animals Experimentally Infected with Fasciola hepatica Metacerariae

• Chun KS
• Min HK

• KMID: 1965155
• DOI: http://doi.org/10.12771/emj.1991.14.1.45

Abstract

The present study was performed to reveal out infection rate. worm recovery rate and individual worm burden in mice rats, rabbits and goats experimentally infected with metacercariae of Fasciola hepatica for establishment of animal model as experimental host of the fluke. Metacercariae were obtained from experimentally infected snails. Lymmaea Pervia. The results obtained are summarised as follows ; 1) Infection rate was 100% in mice, rabbits and goats. respectively, and 73.3% in rats. 2) Days(mean) that eggs were found in the faeces for the first time after infection were 37~46 days(4l days) in mice. 39~49 days(44 days) in rats. 49~63 days(56 days) in rabbits and 68~88 days(78 days) in goats. respectively. The flukes mature more quickly in smaller hosts. 3) Worm recovery rate and mean of individual worm burden were 27.7% and 1.7 in mice. 10.7% and 1.1 in rats. 36.0% and 10.8 in rabbits and 42.7% and 21.3 in goats. respectively. Goats are regarded as favorable experimental hosts of the fluke.

MeSH Terms

Animals
Animals, Laboratory*
Eggs
Fasciola hepatica*
Fasciola*
Goats
Metacercariae
Mice
Models, Animal
Ovum
Rabbits
Rats
Snails
Trematoda