Lab Anim Res.  2010 Dec;26(4):425-428. 10.5625/lar.2010.26.4.425.

Laboratory Rodents Negatively Affected by Construction Environment

• Lee BH
• Jung HD
• Lee BN
• Park KS
• Han JS

• KMID: 2114712
• DOI: http://doi.org/10.5625/lar.2010.26.4.425

Abstract

This report describes rodents in a laboratory animal facility that was adversely affected by a noisy environment during construction work. There was much noise and vibration as well as dust caused by the drilling and hammering. The noise levels, frequencies, and length of time when occurring in the drilling and hammering, were all measured. The drilling showed noise levels ranging from 50-90 decibels (dB) (A-filter, A), and the hammering presented 60-70 dB (A). Some researchers raised problems regarding animal experiments, including skin injuries resulted from self-mutilation, and increase of mortality. This gives useful information to people who plan to renovate laboratory animal facilities as it is a very rare case.

Keyword

Adverse effect; animal welfare; construction; mouse; noisy environment; rat

MeSH Terms

Animal Experimentation
Animal Welfare
Animals
Animals, Laboratory
Dust
Mandrillus
Mice
Noise
Rats
Rodentia
Skin
Vibration
Dust

Figure

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  Figure 1. Diagram of remodeling schedule and noise exposure periods.

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  Figure 2. Various skin injuries caused by self-biting in nude mice (BALB/c nude, CAnN.Cg-Foxn1nu/CrlCrlj, ORIENT BIO INC). They were five weeks old when admitted to the animal facility in the middle of June. Three weeks later injuries were found on the skin of the mice. They were used as the negative control group in a study and were separately housing in each cage operating by individually ventilated cage system.

Reference

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