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Metabolic Crosstalk between the Heart and Fat

Ferrero KM, Koch WJ

It is now recognized that the heart can behave as a true endocrine organ, which can modulate the function of other tissues. Emerging evidence has shown that visceral fat is...
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Impact of Skeletal Muscle Mass on Metabolic Health

Kim G, Kim JH

Skeletal muscle is regarded as an endocrine and paracrine organ. Muscle-derived secretory proteins, referred to as myokines, mediate interactions between skeletal muscle mass and other organs such as the liver,...
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Determinants of Circulating Soluble Leptin Receptor and Free Leptin Index in Indonesian Pre-Pubertal Obese Male Children: A Preliminary Cross-Sectional Study

Hendarto A, Nagrani DG, Meiliana A, Sastroasmoro S, Sjarif DR

PURPOSE: This study aimed to investigate the clinical and metabolic determinants of circulating soluble leptin receptor (CSLR) and free leptin index (FLI) in pre-pubertal obese male children. METHODS: We conducted a...
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Quantification of Fat Concentration and Vascular Response in Brown and White Adipose Tissue of Rats by Spectral CT Imaging

Peng XG, Zhao Z, Chang D, Bai Y, Xu Q, Ju S

OBJECTIVE: The purpose of the study was to non-invasively characterize and discriminate brown adipose tissue (BAT) from white adipose tissue (WAT) in rats using spectral computed tomography (CT) with histological...
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Closure of oroantral fistula: a review of local flap techniques

Kwon MS, Lee BS, Choi BJ, Lee JW, Ohe JY, Jung JH, Hwang BY, Kwon YD

Oroantral fistula (OAF), also termed oroantral communication, is an abnormal condition in which there is a communicating tract between the maxillary sinus and the oral cavity. The most common causes...
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Plasma CD36 and Incident Diabetes: A Case-Cohort Study in Danish Men and Women

Wang Y, Zhu J, Aroner S, Overvad K, Cai T, Yang M, Tjønneland A, Handberg A, Jensen MK

BACKGROUND: Membrane CD36 is a fatty acid transporter implicated in the pathogenesis of metabolic disease. We aimed to evaluate the association between plasma CD36 levels and diabetes risk and to...
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Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women

Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB

BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown....
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Use of SGLT-2 Inhibitors in Patients with Type 2 Diabetes Mellitus and Abdominal Obesity: An Asian Perspective and Expert Recommendations

Sheu WH, Chan SP, Matawaran , Deerochanawong C, Mithal A, Chan J, Suastika K, Khoo CM, Nguyen HM, Linong J, Luk A, Yoon KH

The prevalence of obesity in Asia is of epidemic proportions, with an estimated 1 billion overweight/obese individuals in the region. The majority of patients with type 2 diabetes mellitus (T2DM)...
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Relationship Between Epicardial Fat Volume and Coronary Microvascular Dysfunction in Patients with Chest Pain and Unobstructed Coronary Arteries

Quah JX, Sargent S, Nel K, Anstey CM, Stanton T, Greaves K

OBJECTIVE: Epicardial fat (EF) is metabolically active adipose tissue positioned between the epicardial surface of the heart and the pericardium. We investigated whether there is a relationship between EF and...
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Development and Validation of a Deep Learning System for Segmentation of Abdominal Muscle and Fat on Computed Tomography

Park HJ, Shin Y, Park J, Kim H, Lee IS, Seo DW, Huh J, Lee TY, Park T, Lee J, Kim KW

OBJECTIVE: We aimed to develop and validate a deep learning system for fully automated segmentation of abdominal muscle and fat areas on computed tomography (CT) images. MATERIALS AND METHODS: A fully...
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Application of body composition zones in boys with nonalcoholic fatty liver disease

Choi M, Lee S, Bae SH, Chung S

PURPOSE: Screening nonalcoholic fatty liver disease (NAFLD) by body mass index (BMI) as a single surrogate measure for obesity has limitations. We suggest considering body composition zones by drawing a...
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Perirenal and epicardial fat and their association with carotid intima-media thickness in children

López-Bermejo A, Prats-Puig A, Osiniri I, Martínez-Calcerrada JM, Bassols J

Recent data suggest that subclinical atherosclerosis is more related to visceral adipose tissue distribution than to overall fat mass. Both perirenal fat and epicardial fat are visceral fat depots surrounding...
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Effects of Low-Calorie Diet Including High Protein-Low Carbohydrate Protein Bar on Weight Loss and Serum Lipid Indicators in Overweight Women according to Dietary Compliance

Park D, Lee HJ, Son SM

OBJECTIVES: This study was conducted to investigate the effect of a 6-week low-calorie diet (LCD) program including high protein-low carbohydrate protein bar on weight loss, blood pressure, and blood lipid...
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Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice

Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS

PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL...
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Three Months Monitored Metabolic Fitness Modulates Cardiovascular Risk Factors in Diabetic Patients

Cirilli I, Silvestri , Marcheggiani F, Olivieri F, Galeazzi R, Antonicelli R, Recchioni , Marcheselli F, Bacchetti , Tiano L, Orlando P

Cardiovascular diseases represent the leading cause of death and moderate physical exercise is associated with a reduction in cardiovascular risk. The aim of the study was to evaluate the correlation...
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The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults

Kim JM, Kim BH, Lee H, Kim EH, Kim M, Kim JH, Jeon YK, Kim SS, Kim IJ, Kim YK

BACKGROUND: Thyroid disease and metabolic syndrome are both associated with cardiovascular disease. The aim of this study was to investigate the correlation between thyroid hormones and obesity sub-phenotypes using nationwide...
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Two Faces of White Adipose Tissue with Heterogeneous Adipogenic Progenitors

Hwang I, Kim JB

Chronic energy surplus increases body fat, leading to obesity. Since obesity is closely associated with most metabolic complications, pathophysiological roles of adipose tissue in obesity have been intensively studied. White...
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Adult Stem Cells: Beyond Regenerative Tool, More as a Bio-Marker in Obesity and Diabetes

Sen S

Obesity, diabetes, and cardiovascular diseases are increasing rapidly worldwide and it is therefore important to know the effect of exercise and medications for diabetes and obesity on adult stem cells....
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Differences in dietary intakes, body compositions, and biochemical indices between metabolically healthy and metabolically abnormal obese Korean women

Kang EY, Yim JE

BACKGROUND/OBJECTIVES: There are various factors that affect metabolic abnormalities related to obesity. The purpose of this study is to analyze the differences in dietary intakes and body compositions of obese...
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A Case of Oncocytic Lipoadenoma Arising in the Submandibular Gland

Lee BS, Lee JK, Jang SK, Seo KH, Kim JH, Bang H, Lee DJ

Oncocytic lipoadenoma is a rare salivary gland tumor composed of adipose tissue and oncocytic epithelial cells in varied proportions. We report a case of an oncocytic lipoadenoma of the submandibular...
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