Ann Dermatol.  2009 May;21(2):189-192. 10.5021/ad.2009.21.2.189.

Angiomyxolipoma (Vascular Myxolipoma) of Subcutaneous Tissue

Affiliations
  • 1Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. drkmp@hanmail.net

Abstract

Lipoma is the most common neoplasm of mesenchyme, and several subtypes have been described that vary according to their location and the presence of other tissue elements. Angiomyxolipoma is a very rare variant that consists of an admixture of adipose and myxoid elements with numerous vascular structures. It should be differentiated from other subtypes of benign and malignant lipomas. Here the case of a 69-year-old male is described who presented with a solitary asymptomatic mass on the left iliac crest. The histopathologic findings showed alternating nests of myxoid and adipose tissue containing dilated blood vessels, which was consistent with angiomyxolipoma.

Keyword

Angiomyxolipoma

MeSH Terms

Adipose Tissue
Aged
Blood Vessels
Humans
Lipoma
Male
Mesoderm
Subcutaneous Tissue

Figure

  • Fig. 1 Solitary subcutaneous mass on left iliac crest.

  • Fig. 2 (A) Histopathologic findings show a multilobular mass, composed of adipose tissue and myxoid tissue, surrounded by thin fibrous capsule (H&E stain, ×20). (B) Numerous thin- and thick-walled dilated vessels are found in myxoid and adipose tissue (H&E stain, ×40). (C) Myxoid area shows the presence of abundant mucin (Alcian blue 2.5 stain, ×20). (D) Spindle cells in myxoid area express CD34 (×400).


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Reference

1. Weiss SW, Goldblum JR. Weiss SW, Goldblum JR, Enzinger FM, editors. Benign lipomatous tumors. Enzinger and Weiss's soft tissue tumors. 2001. 4th ed. St. Louis: Mosby;384–430.
2. Mai KT, Yazdi HM, Collins JP. Vascular myxolipoma ("angiomyxolipoma") of the spermatic cord. Am J Surg Pathol. 1996. 20:1145–1148.
Article
3. Zamecnik M. Vascular myxolipoma (angiomyxolipoma) of subcutaneous tissue. Histopathology. 1999. 34:180–181.
4. Sciot R, Debiec-Rychter M, De Wever I, Hagemeijer A. Angiomyxolipoma shares cytogenetic changes with lipoma, spindle cell/pleomorphic lipoma and myxoma. Virchows Arch. 2001. 438:66–69.
Article
5. Tardio JC, Martin-Fragueiro LM. Angiomyxolipoma (vascular myxolipoma) of subcutaneous tissue. Am J Dermatopathol. 2004. 26:222–224.
Article
6. Lee HW, Lee DK, Lee MW, Choi JH, Moon KC, Koh JK. Two cases of angiomyxolipoma (vascular myxolipoma) of subcutaneous tissue. J Cutan Pathol. 2005. 32:379–382.
Article
7. Sanchez Sambucety P, Alonso TA, Agapito PG, Moran AG, Rodriguez Prieto MA. Subungual angiomyxolipoma. Dermatol Surg. 2007. 33:508–509.
Article
8. Kang YS, Choi WS, Lee UH, Park HS, Jang SJ. A case of multiple angiomyxolipoma. Korean J Dermatol. 2008. 46:1090–1095.
9. Fetsch JF, Laskin WB, Tavassoli FA. Superficial angiomyxoma (cutaneous myxoma): a clinicopathologic study of 17 cases arising in the genital region. Int J Gynecol Pathol. 1997. 16:325–334.
Article
10. Warkel RL, Rehme CG, Thompson WH. Vascular spindle cell lipoma. J Cutan Pathol. 1982. 9:113–118.
Article
11. Kilpatrick SE, Doyon J, Choong PF, Sim FH, Nascimento AG. The clinicopathologic spectrum of myxoid and round cell liposarcoma. A study of 95 cases. Cancer. 1996. 77:1450–1458.
Article
12. Huang HY, Lal P, Qin J, Brennan MF, Antonescu CR. Low-grade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems. Hum Pathol. 2004. 35:612–621.
Article
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