Ann Dermatol.  2009 May;21(2):189-192. 10.5021/ad.2009.21.2.189.

Angiomyxolipoma (Vascular Myxolipoma) of Subcutaneous Tissue

• Song M
• Seo SH
• Jung DS
• Ko HC
• Kwon KS
• Kim MB

• KMID: 2219394
• DOI: http://doi.org/10.5021/ad.2009.21.2.189

Abstract

Lipoma is the most common neoplasm of mesenchyme, and several subtypes have been described that vary according to their location and the presence of other tissue elements. Angiomyxolipoma is a very rare variant that consists of an admixture of adipose and myxoid elements with numerous vascular structures. It should be differentiated from other subtypes of benign and malignant lipomas. Here the case of a 69-year-old male is described who presented with a solitary asymptomatic mass on the left iliac crest. The histopathologic findings showed alternating nests of myxoid and adipose tissue containing dilated blood vessels, which was consistent with angiomyxolipoma.

Keyword

Angiomyxolipoma

MeSH Terms

Adipose Tissue
Aged
Blood Vessels
Humans
Lipoma
Male
Mesoderm
Subcutaneous Tissue

Figure

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  Fig. 1 Solitary subcutaneous mass on left iliac crest.

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  Fig. 2 (A) Histopathologic findings show a multilobular mass, composed of adipose tissue and myxoid tissue, surrounded by thin fibrous capsule (H&E stain, ×20). (B) Numerous thin- and thick-walled dilated vessels are found in myxoid and adipose tissue (H&E stain, ×40). (C) Myxoid area shows the presence of abundant mucin (Alcian blue 2.5 stain, ×20). (D) Spindle cells in myxoid area express CD34 (×400).

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