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Neural Stem Cells and Ischemic Brain

Zhang Z, Chopp M

Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within the ischemic brain, neural stem cells, neuroblasts...
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Neural Stem Cells for Neurological Disorders

Roh JK, Kim M, Chu K

Recent progress shows that neurons suitable for transplantation can be generated from neural stem cells (NSCs) in culture, and that the adult brain produces new neurons from its own stem...
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Clinical Applications of Neural Stem Cells for the Treatment of Peripheral Neuropathy

Park JM, Choi BO

Extraordinary advances in stem cell research have initiated an era of hope for strategies to treat intractable human diseases. Personalized regenerative treatment using stem cells is expected to accelerate continuous...
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Regulation of Neural Stem Cell Fate by Natural Products

Kim HJ

Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent...
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Effects of Propofol in Voltage-dependent Potassium Channels in Human Neurl Stem Cells

Kim BY, Bae JH

  • KMID: 2298542
  • Korean J Aerosp Environ Med.
  • 2000 Sep;10(3):241-246.
BACKGROUND: Human neural stem cells have at least two types of voltage-dependent potassium channels including inward and outward rectifying potassium channels. Data for the effects of propofol, intravenous anesthetics, on...
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Combination Cell Therapy with Mesenchymal Stem Cells and Neural Stem Cells for Brain Stroke in Rats

Hosseini S, Farahmandnia M, Razi Z, Delavari S, Shakibajahromi B, Sarvestani FS, Kazemi S, Semsar M

OBJECTIVES: Brain stroke is the second most important events that lead to disability and morbidity these days. Although, stroke is important, there is no treatment for curing this problem. Nowadays,...
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Adult Neurogenesis in the Central and Peripheral Nervous Systems

Kim HJ, Sun W

  • KMID: 2232828
  • Int Neurourol J.
  • 2012 Jun;16(2):57-61.
Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural...
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SoxD Transcription Factors: Multifaceted Players of Neural Development

Ji EH, Kim J

SoxD transcription factor subfamily includes three members, Sox5, Sox6, and Sox13. Like other Sox genes, they contain the High-Mobility-Group (HMG) box as the DNA binding domain but in addition feature...
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Establishment of a Method for Cryopreservation of Neural Stem Cells

Kwon KW, Kim MR, Kim HS, Lee YD, Kim SS

  • KMID: 2092846
  • Korean J Anat.
  • 2004 Dec;37(6):499-508.
Neural stem cells are multipotent stem cells that can differentiate into neurons and glial cells. Neural stem cells are found in not only developing nervous system but some restricted regions...
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Stem Cells in Drug Screening for Neurodegenerative Disease

Kim HJ, Jin CY

Because the average human life span has recently increased, the number of patients who are diagnosed with neurodegenerative diseases has escalated. Recent advances in stem cell research have given us...
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Endogenous Neurogenesis in Postnatal Brain

Chang YS

  • KMID: 1629573
  • Korean J Pediatr.
  • 2005 Aug;48(8):806-812.
Repair mechanisms in the postnatal and mature central nervous system (CNS) have long been thought to be very limited. However recent works have shown that the mature CSN contains neural...
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Differentiation of Rat Neural Stem Cells Following Transplantation in the Brain of Huntington's Disease Rat Model

Ryu HL, Lee SY, Park K, Kim C, Jin BK, Min CK

Stem cells provide an important means for regenerative medicine due to the capacity to generate multiple types of differentiated cells and at the same time to maintain self-renewal. To identify...
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Roles of mTOR Signaling in Brain Development

Lee DY

mTOR is a serine/threonine kinase composed of multiple protein components. Intracellular signaling of mTOR complexes is involved in many of physiological functions including cell survival, proliferation and differentiation through the...
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Neural Stem Cells

Park KI

Multipotent neural stem cells (NSCs) are operationally defined by their ability to self-renew, to differentiate into cells of all glial and neuronal lineages throughout the neuraxis, and to populate developing...
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Transplantation of Neural Stem Cells in Anosmic Mice

Lee CH, Jeon SW, Seo BS, Mo JH, Jeon EH, Choi AR, Kim JW

OBJECTIVES: Treating olfactory dysfunction is a challenge for physicians. One of the therapeutic options could be transplantation of stem cells. In this study, neural stem cells were transplanted into anosmic...
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Autophagy Mediates Astrogenesis in Adult Hippocampal Neural Stem Cells

Ha S, Jeong SH, Yi K, Chu JJ, Kim S, Kim EK, Yu SW

Neural stem cells (NSCs) have the ability to self-renew and differentiate into neurons, oligodendrocytes, and astrocytes. Highly dynamic nature of NSC differentiation requires the intimate involvement of catabolic processes such...
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A Novel Cell Therapy Method for Recovering after Brain Stroke in Rats

Hosseini S, Farahmandnia M, Kazemi S, Shakibajahromi B, Sarvestani FS, Khodabande Z

BACKGROUND: Nowadays, stroke leads to a significant part of the adult mortality and morbidity and also it could result in some neurological deficits in the patients' lives. Cell therapy has...
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Spinal Cord Regeneration in Rat using Neural Stem Cell Differentiated from Human Telencephalon

Kim SR, Chung KH, Lee KB

PURPOSE: To evaluate the effect of neural stem cells differentiated from a human telencephalon on the neural regeneration in the severed spinal cord. MATERIALS AND METHODS: The 1st surgery involving the...
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Comparison of Ectopic Gene Expression Methods in Rat Neural Stem Cells

Kim W, Kim JH, Kong SY, Park MH, Sohn UD, Kim HJ

Neural stem cells (NSCs) have the ability to proliferate and differentiate into various types of cells that compose the nervous system. To study functions of genes in stem cell biology,...
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Comparison of Human Muscle-Derived Stem Cells and Human Adipose-Derived Stem Cells in Neurogenic Trans-Differentiation

Kwon EB, Lee JY, Piao S, Kim IG, Ra JC, Lee JY

  • KMID: 2315549
  • Korean J Urol.
  • 2011 Dec;52(12):852-857.
PURPOSE: Erectile dysfunction (ED) remains a major complication from cavernous nerve injury during radical prostatectomy. Recently, stem cell treatment for ED has been widely reported. This study was conducted to...
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