Korean J Med.  2019 Apr;94(2):145-151. 10.3904/kjm.2019.94.2.145.

Current Stem Cell Therapy for Osteoarthritis

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. juji@catholic.ac.kr

Abstract

Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician's office. There is a growing need, therefore, for physicians to pay attention to this common orthopedic condition. Cartilage degeneration, arthritic pain, and joint dysfunction are major manifestations of osteoarthritis, and degenerated cartilage is difficult to repair with conventional treatment modalities. Scientists and physicians have developed various therapeutic strategies, including the use of stem cells. Here, we discuss previous and current progress in cartilage regenerative therapy against osteoarthritis.

Keyword

Osteoarthritis; Cartilage; Adult stem cells; Induced pluripotent stem cells; Chondrogenesis

MeSH Terms

Adult Stem Cells
Aging
Cartilage
Chondrogenesis
Induced Pluripotent Stem Cells
Joints
Musculoskeletal Diseases
Orthopedics
Osteoarthritis*
Physicians' Offices
Stem Cells*
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