J Korean Orthop Assoc.  2023 Dec;58(6):441-451. 10.4055/jkoa.2023.58.6.441 .

Stem Cell Therapy in Cartilage

• Jung SH
• Choi CH
• Jung M

• KMID: 2549818
• DOI: http://doi.org/10.4055/jkoa.2023.58.6.441

Abstract

Cartilage injury is one of the common problems in a joint with a broad spectrum, from isolated articular cartilage defects to end-stage osteoarthritis. Cartilage has limited regenerative potential, which is more prominent in the elderly patients. Various surgical techniques are performed as treatments for articular cartilage defects. Nevertheless, all existing treatment methods for cartilage damage have their limitations. Hence, stem cell therapy in cartilage has attracted attention as a potential strategy. This review provides information on various stem cell therapies in cartilage currently performed in the orthopedic area. Research progress in this area and the future direction are also described.

Keyword

osteoarthritis; cartilage; articular; regeneration; mesenchymal stem cell