- Macakurzin C Derivatives as a Novel Pharmacophore for Pan-Peroxisome Proliferator-Activated Receptor Modulator
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Ko H, An S, Jang H, Ahn S, Park IG, Hwang SY, Gong J, Oh S, Kwak SY, Choi WJ, Kim H, Noh M
- KMID: 2541790
- Biomol Ther.
- 2023 May;31(3):312-318.
- doi: 10.4062/biomolther.2022.097
The natural flavonoid macakurzin C (1) exhibited adiponectin biosynthesis-inducing activity during adipogenesis in human bone marrow mesenchymal stem cells and its molecular mechanism was directly associated with a pan-peroxisome proliferator-activated... -
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- Assessment of Esophageal Reconstruction via Bioreactor Cultivation of a Synthetic Scaffold in a Canine Model
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Kim IG, Wu Y, Park SA, Choi JS, Kwon SK, Choi SH, Jung KC, Shin JW, Chung EJ
- KMID: 2542358
- Clin Exp Otorhinolaryngol.
- 2023 May;16(2):165-176.
- doi: 10.21053/ceo.2022.01522
Objectives. Using tissue-engineered materials for esophageal reconstruction is a technically challenging task in animals that requires bioreactor training to enhance cellular reactivity. There have been many attempts at esophageal tissue... -
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- Exosomes Derived from Human Amniotic Mesenchymal Stem Cells Facilitate Diabetic Wound Healing by Angiogenesis and Enrich Multiple lncRNAs
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Fu S, Zhang H, Li X, Zhang Q, Guo C, Qiu K, Feng J, Liu X, Liu D
- KMID: 2541494
- Tissue Eng Regen Med.
- 2023 Apr;20(2):295-308.
- doi: 10.1007/s13770-022-00513-w
BACKGROUND: Diabetic wound healing remains a major challenge due to the impaired functionality of angiogenesis by persistent hyperglycemia. Mesenchymal stem cell exosomes are appropriate candidates for regulating the formation of... -
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- Matrix Metalloproteinase 1 as a Marker of Tonsil-Derived Mesenchymal Stem Cells to Assess Bone Marrow Cell Migration
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Kim HY, Yoon HS, Lee Y, Kim YH, Cho KA, Woo SY, Kim HS, Ryu KH, Park JW
- KMID: 2541492
- Tissue Eng Regen Med.
- 2023 Apr;20(2):271-284.
- doi: 10.1007/s13770-022-00501-0
BACKGROUND: To achieve optimal bone marrow engraftment during bone marrow transplantation, migration of donor bone marrow cells (BMCs) toward the recipient’s bone marrow is critical. Despite the enhanced engraftment of... -
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- Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats
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Kim WH, Yoo JH, Yoo IK, Kwon CI, Hong SP
- KMID: 2539559
- Yonsei Med J.
- 2023 Mar;64(3):167-174.
- doi: 10.3349/ymj.2022.0342
Purpose: There are no effective treatment methods with which to control complications of radiation proctitis with fistula or recurrent bleeding following radiation treatment for prostate, cervical, or rectal cancer. Mesenchymal... -
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- Combinatorial Effect of Mesenchymal Stem Cells and Extracellular Vesicles in a Hydrogel on Cartilage Regeneration
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Cho WJ, Ahn J, Lee M, Choi H, Park S, Cha KY, Lee S, Arai Y, Lee SH
- KMID: 2539238
- Tissue Eng Regen Med.
- 2023 Feb;20(1):143-154.
- doi: 10.1007/s13770-022-00509-6
BACKGROUND: Mesenchymal stem cells (MSCs) are used for tissue regeneration due to their wide differentiation capacity and anti-inflammatory effects. Extracellular vesicles (EVs) derived from MSCs are also known for their... -
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- Synergistic Effect of Hydrogen and 5-Aza on Myogenic Differentiation through the p38 MAPK Signaling Pathway in Adipose-Derived Mesenchymal Stem Cells
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Fei W, Pang E, Hou L, Dai J, Liu M, Wang X, Xie B, Wang J
- KMID: 2539623
- Int J Stem Cells.
- 2023 Feb;16(1):78-92.
- doi: 10.15283/ijsc21238
Background and Objectives: This study aims to clarify the systems underlying regulation and regulatory roles of hydrogen combined with 5-Aza in the myogenic differentiation of adipose mesenchymal stem cells (ADSCs). Methods... -
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- Transplantation of Differentiated Tonsil-Derived Mesenchymal Stem Cells Ameliorates Murine Duchenne Muscular Dystrophy via Autophagy Activation
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Park S, Jeong S, Nam YH, Yum Y, Jung SC
- KMID: 2536458
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1283-1294.
- doi: 10.1007/s13770-022-00489-7
BACKGROUND: Skeletal muscles play many important roles in the human body and any malfunction or disorder of the skeletal muscles can lead to a reduced quality of life. Some skeletal... -
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- The Role of Low-Frequency Electromagnetic Fields on Mesenchymal Stem Cells Differentiation: A Systematic Review
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Safavi AS, Sendera A, Haghighipour N, Banas-Zabczyk A
- KMID: 2536446
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1147-1160.
- doi: 10.1007/s13770-022-00473-1
BACKGROUND Low-frequency electromagnetic fields (EMFs) influence biological processes. This present study was aimed at the scientific literature on the use of EMFs in the mesenchymal stem cell differentiation process. MATERIALS AND... -
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- L-Theanine-Treated Adipose-Derived Mesenchymal Stem Cells Alleviate the Cytotoxicity Induced by N-Nitrosodiethylamine in Liver
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Lai YJ, Sung YT, Lai YA, Chen LN, Chen TS, Chien CT
- KMID: 2536452
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1207-1221.
- doi: 10.1007/s13770-022-00472-2
BACKGROUND: Liver inflammation is the main cause of severe liver diseases, including liver fibrosis, steatohepatitis, cirrhosis and hepatocellular carcinoma. Cell therapy topics are receiving increasingly more attention. The therapeutic applications... -
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- MSCs-Derived miR-150-5p-Expressing Exosomes Promote Skin Wound Healing by Activating PI3K/AKT Pathway through PTEN
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Xiu C, Zheng H, Jiang M, Li J, Zhou Y, Mu L, Liu W
- KMID: 2536206
- Int J Stem Cells.
- 2022 Nov;15(4):359-371.
- doi: 10.15283/ijsc21135
Background and Objectives: The goal of this study was to investigate the mechanism of mesenchymal stem cell (MSC)-derived microRNA (miR)-150-5p-expressing exosomes in promoting skin wound healing through activating PI3K/AKT pathway... -
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- Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model
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Mo Y, Kim Y, Bang JY, Jung J, Lee CG, Elias JA, Kang HR
- KMID: 2536267
- Immune Netw.
- 2022 Oct;22(5):e40.
- doi: 10.4110/in.2022.22.e40
Mesenchymal stem cells (MSCs) are attractive alternatives to conventional anti-asthmatic drugs for severe asthma. Mechanisms underlying the anti-asthmatic effects of MSCs have not yet been elucidated. This study evaluated the... -
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- Basic Fibroblast Growth Factor Induces Cholinergic Differentiation of Tonsil-Derived Mesenchymal Stem Cells
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Song JH, Oh SY, Jo SA
- KMID: 2533934
- Tissue Eng Regen Med.
- 2022 Oct;19(5):1063-1075.
- doi: 10.1007/s13770-022-00474-0
BACKGROUND: Mesenchymal stem cells (MSCs) are considered a potential tool for regenerating damaged tissues due to their great multipotency into various cell types. Here, we attempted to find the appropriate... -
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- Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging
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Wu JY, Wu SN, Zhang LP, Zhao XS, Li Y, Yang QY, Yuan RY, Liu JL, Mao HJ, Zhu NW
- KMID: 2533927
- Tissue Eng Regen Med.
- 2022 Oct;19(5):961-968.
- doi: 10.1007/s13770-022-00461-5
Senescence is an inevitable natural life process that involves structural and functional degeneration of tissues and organs. Recently, the process of skin aging has attracted much attention. Determining a means... -
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- A Comprehensive Cancer-Associated MicroRNA Expression Profiling and Proteomic Analysis of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes
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Jothimani G, Pathak S, Dutta S, Duttaroy AK, Banerjee A
- KMID: 2533931
- Tissue Eng Regen Med.
- 2022 Oct;19(5):1013-1031.
- doi: 10.1007/s13770-022-00450-8
BACKGROUND: The mesenchymal stem cells (MSCs) have enormous therapeutic potential owing to their multi-lineage differentiation and self-renewal properties. MSCs express growth factors, cytokines, chemokines, and non-coding regulatory RNAs with immunosuppressive,... -
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- In Situ-Forming Collagen/poly-γ-glutamic Acid Hydrogel System with Mesenchymal Stem Cells and Bone Morphogenetic Protein-2 for Bone Tissue Regeneration in a Mouse Calvarial Bone Defect Model
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Cho SH, Shin KK, Kim SY, Cho MY, Oh DB, Lim YT
- KMID: 2533937
- Tissue Eng Regen Med.
- 2022 Oct;19(5):1099-1111.
- doi: 10.1007/s13770-022-00454-4
BACKGROUND: Bone marrow-derived mesenchymal stem cells (BMSCs) and bone morphogenetic protein-2 (BMP-2) have been studied for bone repair because they have regenerative potential to differentiate into osteoblasts. The development of... -
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- Identification of Key microRNAs in Diabetes Mellitus Erectile Dysfunction Rats with Stem Cell Therapy by Bioinformatic Analysis of Deep Sequencing Data
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Kang J, Song Y, Zhang Z, Wang S, Lu Y, Liu X
- KMID: 2537114
- World J Mens Health.
- 2022 Oct;40(4):663-677.
- doi: 10.5534/wjmh.210147
Purpose: Diabetes mellitus erectile dysfunction (DMED) is a common resulting complication of diabetes. Studies have shown mesenchymal stem cell (MSC)-based therapy was beneficial in alleviating erectile function of DMED rats.... -
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- Therapeutic Effect of Human Mesenchymal Stem Cell-Conditioned Medium on Erectile Dysfunction
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Kim SG, You D, Kim K, Aum J, Kim YS, Jang MJ, Moon KH, Kang HW
- KMID: 2537113
- World J Mens Health.
- 2022 Oct;40(4):653-662.
- doi: 10.5534/wjmh.210121
Purpose: Owing to the safety and cost effectiveness of conditioned medium (CM), its therapeutic effects have attracted significant attention from many researchers. To date, numerous studies have been conducted on... -
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- Multimodal Repair of Spinal Cord Injury With Mesenchymal Stem Cells
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Ma Yh, Liang Qy, Ding Y, Han I, Zeng X
- KMID: 2533789
- Neurospine.
- 2022 Sep;19(3):616-629.
- doi: 10.14245/ns.2244272.136
Spinal cord injury (SCI) is a result of a devastating injury to the central nervous system. Currently, there is no effective treatment available for these patients. The possible use of... -
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- Photobiomodulation improves the therapeutic efficacy of mesenchymal stem cells in regenerative medicine
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Woo K, Abueva C
- KMID: 2533588
- Med Lasers.
- 2022 Sep;11(3):134-142.
- doi: 10.25289/ML.2022.11.3.134
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into many other cell types typically isolated from adult tissue sources. The therapeutic potential of MSCs is considerable in... -
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