- Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system
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Wei R, Lv J, Li X, Li Y, Xu Q, Jin J, Zhang Y, Liu Z
- KMID: 2469024
- J Vet Sci.
- 2020 Jan;21(1):e9.
- doi: 10.4142/jvs.2020.21.e9
Regenerative therapy holds great promise in the development of cures of some untreatable diseases such as cardiovascular diseases, and pluripotent stem cells (PSCs) including induced PSCs (iPSCs) are the most... -
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- Maintenance of hPSCs under Xeno-Free and Chemically Defined Culture Conditions
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Lim JJ, Kim HJ, Rhie BH, Lee MR, Choi MJ, Hong SH, Kim KS
- KMID: 2465889
- Int J Stem Cells.
- 2019 Nov;12(3):484-496.
- doi: 10.15283/ijsc19090
Previously, the majority of human embryonic stem cells and human induced pluripotent stem cells have been derived on feeder layers and chemically undefined medium. Those media components related to feeder... -
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- Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients
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Lee M, Sim H, Ahn H, Ha J, Baek A, Jeon YJ, Son MY, Kim J
- KMID: 2465888
- Int J Stem Cells.
- 2019 Nov;12(3):474-483.
- doi: 10.15283/ijsc19075
In Parkinson’s disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as in vitro models. The advancement in the field of reprogramming technology has provided... -
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- Reprogramming of Cancer Cells into Induced Pluripotent Stem Cells Questioned
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Bang JS, Choi NY, Lee M, Ko K, Park YS, Ko K
- KMID: 2465883
- Int J Stem Cells.
- 2019 Nov;12(3):430-439.
- doi: 10.15283/ijsc19067
BACKGROUND AND OBJECTIVES: Several recent studies have claimed that cancer cells can be reprogrammed into induced pluripotent stem cells (iPSCs). However, in most cases, cancer cells seem to be resistant... -
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- Stem cell therapy in pain medicine
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Han YH, Kim KH, Abdi S, Kim TK
- KMID: 2462834
- Korean J Pain.
- 2019 Oct;32(4):245-255.
- doi: 10.3344/kjp.2019.32.4.245
Stem cells are attracting attention as a key element in future medicine, satisfying the desire to live a healthier life with the possibility that they can regenerate tissue damaged or... -
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- Human Induced Pluripotent Stem Cells: Clinical Significance and Applications in Neurologic Diseases
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Chang EA, Jin SW, Nam MH, Kim SD
- KMID: 2457939
- J Korean Neurosurg Soc.
- 2019 Sep;62(5):493-501.
- doi: 10.3340/jkns.2018.0222
The generation of human induced pluripotent stem cells (iPSCs) from somatic cells using gene transfer opens new areas for precision medicine with personalized cell therapy and encourages the discovery of... -
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- Comparative Evaluation of Hormones and Hormone-Like Molecule in Lineage Specification of Human Induced Pluripotent Stem Cells
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Choi SA, An JH, Lee SH, Lee GH, Yang HJ, Jeong PS, Cha JJ, Lee S, Park YH, Song BS, Sim BW, Kim YH, Kim JS, Jin YB, Huh JW, Lee SR, Lee JH, Kim SU
- KMID: 2465895
- Int J Stem Cells.
- 2019 Jul;12(2):240-250.
- doi: 10.15283/ijsc18137
BACKGROUND AND OBJECTIVES: Proficient differentiation of human pluripotent stem cells (hPSCs) into specific lineages is required for applications in regenerative medicine. A growing amount of evidences had implicated hormones and... -
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- Regenerative Medicine of the Bile Duct: Beyond the Myth
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Buisson EM, Jeong J, Kim HJ, Choi D
- KMID: 2465890
- Int J Stem Cells.
- 2019 Jul;12(2):183-194.
- doi: 10.15283/ijsc18055
Cholangiopathies are rare diseases of the bile duct with high mortality rates. The current treatment for cholangiopathies is liver transplantation, but there are significant obstacles including a shortage of donors... -
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- Clinical and genetic aspects of Charcot-Marie-Tooth disease subtypes
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Nam SH, Choi BO
- KMID: 2469528
- Precis Future Med.
- 2019 Jun;3(2):43-68.
- doi: 10.23838/pfm.2018.00163
Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neuropathies and is both genetically and clinically heterogeneous, with variable inheritance modes. With regard to clinical and genetic aspects, CMT... -
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- Recovery of Spermatogenesis Following Cancer Treatment with Cytotoxic Chemotherapy and Radiotherapy
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Okada K, Fujisawa M
- KMID: 2443232
- World J Mens Health.
- 2019 May;37(2):166-174.
- doi: 10.5534/wjmh.180043
The survival rates of boys and men with cancer have increased due to advances in cancer treatments; however, maintenance of quality of life, including fertility preservation, remains a major issue.... -
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- Conditioned Medium Enhances Osteogenic Differentiation of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells
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Zhong S, He X, Li Y, Lou X
- KMID: 2449245
- Tissue Eng Regen Med.
- 2019 Apr;16(2):141-150.
- doi: 10.1007/s13770-018-0173-3
BACKGROUND: Recent studies have shown that induced pluripotent stem cells (iPSCs) could be differentiated into mesenchymal stem cells (MSCs) with notable advantages over iPSCs per se. In order to promote... -
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- Stem Cell-Based Therapies for Liver Diseases: An Overview and Update
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Wang J, Sun M, Liu W, Li Y, Li M
- KMID: 2449242
- Tissue Eng Regen Med.
- 2019 Apr;16(2):107-118.
- doi: 10.1007/s13770-019-00178-y
BACKGROUND: Liver disease is one of the top causes of death globally. Although liver transplantation is a very effective treatment strategy, the shortage of available donor organs, waiting list mortality,... -
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- Current Stem Cell Therapy for Osteoarthritis
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Nam Y, Rim YA, Ju JH
- KMID: 2446968
- Korean J Med.
- 2019 Apr;94(2):145-151.
- doi: 10.3904/kjm.2019.94.2.145
Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician's office. There... -
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- Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation
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Lee HJ, Choi NY, Lee SW, Lee Y, Ko K, Kim GJ, Hwang HS, Ko K
- KMID: 2447222
- Int J Stem Cells.
- 2019 Mar;12(1):31-42.
- doi: 10.15283/ijsc18084
BACKGROUND AND OBJECTIVES: Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been used to study genomic imprinting, there... -
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- Regulation of Neural Stem Cell Fate by Natural Products
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Kim HJ
- KMID: 2432062
- Biomol Ther.
- 2019 Jan;27(1):15-24.
- doi: 10.4062/biomolther.2018.184
Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent... -
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- Mbd3 Promotes Reprogramming of Primary Human Fibroblasts
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Jaffer S, Goh P, Abbasian M, Nathwani A
- KMID: 2429556
- Int J Stem Cells.
- 2018 Nov;11(2):235-241.
- doi: 10.15283/ijsc18036
Mbd3 (Methyl-CpG binding domain protein), a core member of NuRD (nucleosome remodelling and deacetylation) is essential for embryogenesis. However, its role in reprogramming of somatic cells into induced pluripotent stem... -
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- Cardiac Regeneration with Human Pluripotent Stem Cell-Derived Cardiomyocytes
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Park M, Yoon YS
- KMID: 2422545
- Korean Circ J.
- 2018 Nov;48(11):974-988.
- doi: 10.4070/kcj.2018.0312
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which are collectively called pluripotent stem cells (PSCs), have emerged as a promising source for regenerative medicine. Particularly, human pluripotent... -
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- Storage and use of cord blood
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Lee YH
- KMID: 2420367
- J Korean Med Assoc.
- 2018 Sep;61(9):557-565.
- doi: 10.5124/jkma.2018.61.9.557
Cord blood (CB) has been used as an important source for hematopoietic stem cell transplantation and has been stored in public CB banks (CBBs) worldwide since the mid-1990s. Recently, the... -
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- Suppression of the ERK–SRF axis facilitates somatic cell reprogramming
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Huh S, Song HR, Jeong GR, Jang H, Seo NH, Lee JH, Yi JY, Lee B, Choi HW, Do JT, Kim JS, Lee SH, Jung JW, Lee T, Shim J, Han MK, Lee TH
- KMID: 2440030
- Exp Mol Med.
- 2018 Feb;50(2):e448.
- doi: 10.1038/emm.2017.279
The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination... -
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- Trans-differentiation via Epigenetics: A New Paradigm in the Bone Regeneration
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Cho YD, Ryoo HM
- KMID: 2406234
- J Bone Metab.
- 2018 Feb;25(1):9-13.
- doi: 10.11005/jbm.2018.25.1.9
In regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patient's own cells... -
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