J Korean Neuropsychiatr Assoc.
1998 Jul;37(4):758-761.
Risperidone-Induced Amenorrhea in a Premenopausal Woman with Schizophrenia
- Affiliations
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- 1Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea.
Abstract
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The incidence of risperidone-induced amenorrhea has not been well known. Since conven tional antipsyrchotics-induced amenorrhea may be due to the hyperprolactinemia associated with the block of dopamine D2 receptor, it seems justified to expect that risperidone having the affinities far dopamine and serotonin receptor also may induce the hyperprolactinemia and the amenorrhea. We report the case of risperidone-induced amenorrhea in a premenopausal woman with schizophrenia. The amenorrhea of the patient would be related to the hyperprolactinemia. Clinicians should be vigilant to the possible reaction in their female patients with schizophrenia.