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Schizophrenia in Late Life

Shin SE

  • KMID: 2014948
  • J Korean Geriatr Psychiatry.
  • 2009 Jun;13(1):19-23.
This article has reviewed general characters of schizophrenia in late life. Specifically, it has reviewed epidemiology, course, and several results of biological researches and so on of schizophrenia in old...
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Treatment-Resistant Schizophrenia : Pathophysiology and Treatment

Kim E

A large proportion of patients with schizophrenia show a poor response to first-line antipsychotic drugs, which is termed treatment-resistant schizophrenia. Previous studies found that a different neurobiology might underlie treatment-resistant...
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Role of Serotonin in Pathophysiology and Treatment of Schizophrenia

Park SY, Hahn KH

  • KMID: 2202976
  • J Korean Soc Biol Psychiatry.
  • 1997 Nov;4(2):162-167.
There is no doubt that dopamine plays a critical role in the etiopathogenesis of schizophrenia. However, there appeared some limitations in explaining the complex phenomena of schizophrenia. Recent research data...
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Memory Disorder in Schizophrenia

Jon DI

  • KMID: 2317277
  • Sleep Med Psychophysiol.
  • 1997 Jun;4(1):39-48.
Memory disorder is the most consistent neuropsychological finding in schizophrenia and seems to be a stable trait in it. It is suggested that memory dysfunction found in patients with schizophrenia...
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Neuroimaging Findings in Subjects at High Risk for Developing Schizophrenia

Choi JS, Kwon JS

  • KMID: 2341481
  • J Korean Neuropsychiatr Assoc.
  • 2008 Sep;47(5):430-440.
The pathophysiology of schizophrenia may be influenced by interaction of genetic, neurodevelopmental, environmental and/or psychological factors, which make it difficult to elucidate the etiology of the disorders through clinical phenomenology....
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Cognitive Rehabilitation for Schizophrenia

Lee HS, An SK, Lee MH

  • KMID: 2340136
  • J Korean Neuropsychiatr Assoc.
  • 1998 Mar;37(2):203-214.
It is widely accepted that patients with schizophrenia show disturbances in their cognitive function. Recently, due to the increase of the possibilities of therapeutic intervention for cognitive deficits, cognitive rehabilitation...
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Eye Movement and Schizophrenia

Kim CE

  • KMID: 2317257
  • Sleep Med Psychophysiol.
  • 1996 Jun;3(1):3-14.
Eye movement dysfunction has been found in large numbers of schizophrenia patients and their first-degree relatives and can be studied without the interference of deficits in attention, motivation, clinical status...
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Prefrontal Cortex and Schizophrenia

Chung YC, Eun HB

  • KMID: 2334567
  • J Korean Soc Biol Psychiatry.
  • 1998 Nov;5(2):184-196.
With a rapid development of neuroscience, the theories related to the pathophysiology of schizophrenia have been changed a lot from a simple hyperdopaminergic one to the various complicated ones. Among...
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Concept and Neurobiology of Social Cognition in Schizophrenia

Lee SH, Jung HT, Lee J

  • KMID: 2341173
  • J Korean Neuropsychiatr Assoc.
  • 2006 May;45(3):183-190.
Recently, social cognition is becoming a hot issue in field of schizophrenia research. There are increasing demands for more clear definition of terms and knowledge about neurobiology of social cognition...
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Schizophrenia and Immunological Abnormalities

Jung HY, Kim YS

  • KMID: 2029205
  • Korean J Biol Psychiatry.
  • 2008 Aug;15(3):152-174.
There have been vast amount studies regarding immunologic dysregulation in schizophrenia. The mechanism of immune pathogenesis in schizophrenia still is unclear, even though various immune dysfunction have been reported. We...
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Neurophyisological and Neurocognitive Endophenotypes for Schizophrenia Genetics Research

Joo YH

  • KMID: 2315798
  • Psychiatry Investig.
  • 2008 Dec;5(4):199-202.
There is growing interest in the genetic analysis of schizophrenia using endophenotypes rather than clinical diagnosis or symptom dimensions. Endophenotypes could be alternative phenotypes for the clinical phenotypes. With their...
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Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Tripathi A, Kar SK, Shukla R

Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the course of schizophrenia, after being originated even before the onset of illness. Existing pharmacological and biological...
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Nitric Oxide and Schizophrenia

Chung YI

  • KMID: 2286915
  • Korean J Psychopharmacol.
  • 2001 Sep;12(3):169-176.
Schizophrenia is one of the most serious mental disorders affecting around 1% of the world population, yet the pathophysiology of this disorder remains largely unknown. Nitric oxide (NO) has recently...
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Brain MRI Findings for the Patient with the Late Onset Schizophrenia: Comparison among Patients with the Early Onset Schizophrenia, Progressive Schizophrenia, Senile Dementia and Controls

Park DS, Lee YH, Choi YH, Park YS, Chung YC

  • KMID: 1944948
  • J Korean Soc Biol Psychiatry.
  • 1997 Jun;4(1):74-83.
With increasing tendency of incidence and interest for the late onset schzophrenia, concerns about whether this disorder is etiologically or phenomenogically distinctive entity or not have increased also. To clarify...
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Neuropsycholgical Fingings in Schizophrenia

Lee HS

  • KMID: 2317248
  • Sleep Med Psychophysiol.
  • 1995 Dec;2(2):105-114.
Schiophrenia is characterized by a variety of cognitive dysfunctions.A number of research findings suggest that schizophrenic patients have global deficits in cognitive functions, such as attention, memory, executive functions, and...
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Schizophrenia Spectrum Disorder in DSM-5 : Is this a New Change?

Cho CH, Lee HJ

The American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth version (DSM-5) finally introduced in 2013. Psychiatrists and researchers of neuroscience were looking forward that DSM-5 will introduce...
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Late-life Schizophrenia

Lee HS

  • KMID: 2340260
  • J Korean Neuropsychiatr Assoc.
  • 1999 Jan;38(1):12-26.
The author attempted to study on the characteristics of schizophrenia in the elderly by reviewing the literature both on late-onset schizophrenia and early-onset schizophrenia which had extended into middle and...
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Sleep and Schizophrenia

Lee JS

  • KMID: 2317507
  • Sleep Med Psychophysiol.
  • 2011 Dec;18(2):67-71.
Schizophrenia is a chronic, currently incurable, and devastating syndrome. Although sleep disturbances are not primary symptoms of schizophrenia, they are important aspects of schizophrenia. Difficulties initiating or maintaining sleep are...
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The Effects of Insight and Empowerment on Function and Quality of Life for Patients with Schizophrenia

Kim YY, Park HS

PURPOSE: The purpose of this study was to examine whether insight and empowerment had a positive impact on function and quality of life for patients with schizophrenia. METHODS: The subjects consisted...
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Hippocampus and Schizophrenia

Chung YC

  • KMID: 2025725
  • J Korean Soc Biol Psychiatry.
  • 2003 Jun;10(1):20-44.
Schizophrenics suffer not only psychotic symptoms but also cognitive deficits such as an attentional difficulty, memory impairment, poor abstraction, etc. These cognitive abnormalities have been reported to be significantly related...
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