Korean J Urol.  1983 Aug;24(4):563-570.

A Review of Urinary Tract Pathogens and their Antibiotic Susceptibility Over a 10 years Period

• Lee BS
• Lee JM

Abstract

In patients with urinary tract infections, institution of specific therapy should be preceded by careful examination of the urine and quantitative bacteriology from properly collected urine specimens. A clinical study on patients with urinary tract infections was done for observation of the changing trend in causative organisms and their antibiotic susceptibility at Yonsei Medical Center for the years 1971, 1976 and 1981. The following results were obtained: 1) In 1971, 571patients (male:211, female:360) with urinary tract infection and in 1976, 647patients (male:265, female:382) and in 1981, 1280patients (male: 471, female: 809) were observed. The ratio of males to females was 1:1.4-1.7, and the majority of the cases(60%) seen in all three sample years occured in patients aged 20-49. 2) In 1971 the most common pathogen were E. coli, enterobacter and paeudomonas in that order. For 1976 the most common pathogens were E. coli, enterobacter, klebsiella and pseudomeonas in that order. For 1981 the most common pathogens were E. coli, klebsiella and pseudomonas in that order. E. coli was the causative organism in 60% of the infections that occured in the female patients, but only 25% of the infections that occured in male patients in all three sample years. 3) The incidence of mixed urinary tract infections was 10.5% in 1971, 15.1% in 1976 and 11.8% in 1981. 4) The susceptibility rates of E. coli were 87.6% to kanamycin and 88.6% to neomycin in 1971 and 93.1% to gentamicin and 85.7% to colistin in 1976 and 92.2% to gentamicin and 98.2% to amikacin in 1981. The susceptibility rate of pseudomonas was 79.5% to colistin in 1971 and 88.7% in 1976 and 63.8% in 1981. Citrobacter, klebsiella, enterobacter and proteus were usually resistant to ampicillin and susceptible to amikacin in 1981. Serratia and acinetobacter were usually resistant to most antibiotics. 5) The susceptibility rate of enterococcus was more than 80% to penicillin in 1971, 1976 and 1981. Staphylococcus and streptococcus were usually resistant to penicillin and susceptible to cephalothin.

MeSH Terms

Acinetobacter
Amikacin
Ampicillin
Anti-Bacterial Agents
Bacteriology
Cephalothin
Citrobacter
Colistin
Enterobacter
Enterococcus
Female
Gentamicins
Humans
Incidence
Kanamycin
Klebsiella
Male
Neomycin
Penicillins
Proteus
Pseudomonas
Serratia
Staphylococcus
Streptococcus
Urinary Tract Infections
Urinary Tract*
Amikacin
Ampicillin
Anti-Bacterial Agents
Cephalothin
Colistin
Gentamicins
Kanamycin
Neomycin
Penicillins