Lab Med Online.  2013 Jan;3(1):34-39. 10.3343/lmo.2013.3.1.34.

Epidemiology and Resistance Patterns of Bacterial Pathogens in Urinary Tract Infections in the Northern Gyeonggi-do Area during 2007-2011

• Oh E
• Lee H
• Lim HS
• Park Y

• KMID: 1845394
• DOI: http://doi.org/10.3343/lmo.2013.3.1.34

Abstract

BACKGROUND
Bacteria that cause urinary tract infections (UTIs) are found with different frequencies in different regions; moreover, antibiotic susceptibility can also vary by region. We retrospectively studied and compared the species and antimicrobial susceptibility of bacterial pathogens isolated from patients with UTIs in the northern Gyeonggi-do area.
METHODS
We analyzed urine specimens collected from patients who visited the Myongji Hospital between 2007 and 2011. The urine specimens were cultured, and bacteria were identified by biochemical examination with an API kit (bioMerieux Inc., USA). Antimicrobial susceptibility was determined by the disc diffusion method and the Vitek II system (bioMerieux Inc., USA).
RESULTS
A total of 11,818 (31.4%) urine specimens were culture positive. The most common species identified were Escherichia coli (37.1%), Klebsiella pneumoniae (7.4%), Enterococcus faecium (6.1%), and Candida spp. (5.5%). The proportion of isolates producing extended-spectrum beta-lactamases significantly increased during the study period.
CONCLUSIONS
E. coli, K. pneumoniae, and E. faecium were the 3 most common organisms identified. Of note, however, was the increasing frequency of Pseudomonas spp. and Proteus spp. isolated during the more recent years. Further studies are required from other centers in the northern Gyeonggi-do area.

Keyword

Urinary tract infection; Urine culture; Antibiotic susceptibility testing

MeSH Terms

Bacteria
beta-Lactamases
Candida
Diffusion
Enterococcus faecium
Escherichia coli
Humans
Klebsiella pneumoniae
Pneumonia
Proteus
Pseudomonas
Retrospective Studies
Urinary Tract
Urinary Tract Infections
beta-Lactamases

Figure

• 

  Fig. 1 Antimicrobial resistance trend of major antibiotic-resistant bacteria isolated from the northern Gyeonggi area hospital. Abbreviations: MRCoNS, methicillin-resistant coagulase-negative staphylococci; VAN-R-EFM, vancomycin-resistant E. faecium; ESBL-ECO, extended-spectrum β-lactamase producing E. coli; ESBL-KPN, extended-spectrum β-lactamase producing K. pneumoniae; MRSA, methicillin-resistant Staphylococcus aureus.

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