Korean J Clin Microbiol.  2007 Apr;10(1):19-24.

Patterns of Antimicrobial Susceptibility of the Causative Bacteria of Urinary Tract Infections in Recent Years in an Island Region

• Kim YR
• Huh JS
• Kang SH

Abstract

BACKGROUND: In order to provide a guideline for empirical treatment of urinary tract infections, we studied a change in causative organisms and antimicrobial susceptibility in our region of an island.
METHODS
We reviewed the results of antimicrobial susceptibility and the hospital charts of 3,064 patients with a significant bacteriuria (more than 105 colony forming unit/mL in urine cultures); the patients had been admitted to or seen at the out-patient clinic of Cheju University Hospital during the period from January 2002 to December 2005.
RESULTS
The most common pathogens were Escherichia coli (44.9%), Klebsiella spp. (8.1%), and Pseudomonas spp. (7.0%). In E. coli, the mean percent resistance to ampicillin, trimethoprim-sulfamethoxazole, and ciprofloxacin during the 4-year period was 69.0%, 32.5%, and 24.7%, respectively.
CONCLUSION
An increasing resistance of common urinary pathogens to known empirical agents such as ampicillin, trimethoprim-sulfamethoxazole, and ciprofloxacin caused a need for a more updated guideline in our region of an island.

Keyword

Urinary tract infections; Antimicrobial susceptibility

MeSH Terms

Ampicillin
Bacteria*
Bacteriuria
Ciprofloxacin
Escherichia coli
Humans
Jeju-do
Klebsiella
Outpatients
Pseudomonas
Trimethoprim, Sulfamethoxazole Drug Combination
Urinary Tract Infections*
Urinary Tract*
Ampicillin
Ciprofloxacin