Korean J Pediatr.  2010 Jan;53(1):106-110. 10.3345/kjp.2010.53.1.106.

A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding

Affiliations
  • 1Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine, Seoul, Korea. joonsl96@yuhs.ac
  • 2Department of Neurosurgery, Severance Children's Hospital Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Severance Children's Hospital Yonsei University College of Medicine, Seoul, Korea.

Abstract

Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.

Keyword

Hippocampus; Cortical dysplasia; Epilepsy; Surgery; MRI

MeSH Terms

Atrophy
Brain
Epilepsy
Epilepsy, Temporal Lobe
Hand
Hippocampus
Humans
Magnetic Resonance Imaging
Malformations of Cortical Development
Sclerosis
Sensitivity and Specificity
Temporal Lobe
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