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Delayed Diagnosis of Chromosome 22q11.2 Deletion Syndrome Due to Late-Onset Generalized Epilepsy

Lee SK, Lee EJ, Kwun KH, Kim TJ, Lee SK

No abstract available.
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Antiphospholipid and Antinuclear Antibodies in Children with Idiopathic Epilepsy: A 2-Year Prospective Study

Attilakos , Fotis L, Dinopoulos A, Alexopoulos H, Theofilopoulou AV, Tzioufas A, Mastroyianni S, Karalexi M, Garoufi A

BACKGROUND AND PURPOSE: The high prevalence of antiphospholipid antibodies (aPL) and antinuclear antibodies (ANA) in patients with epilepsy may be associated with either the disease itself or the antiepileptic treatment....
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Real-Life Effectiveness and Tolerability of Perampanel in Pediatric Patients Aged 4 Years or Older with Epilepsy: A Korean National Multicenter Study

Hwang SK, Lee YJ, Nam SO, Kim WS, Kim JS, Kim SJ, Lee YJ, Kwon S

BACKGROUND AND PURPOSE: The US Food and Drug Administration approval for perampanel has only recently been expanded to patients as young as 4 years, and so there have been few...
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Effects of Lamotrigine on Problem-Solving Abilities in Newly Diagnosed Pediatric Patients with Epilepsy

Lee SH, Kim SJ

BACKGROUND AND PURPOSE: This study aimed to determine the effects of lamotrigine (LTG) on language unction, including problem-solving abilities, in newly diagnosed pediatric epileptic patients. METHODS: This study included 112 newly...
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Effect of Repetitive Transcranial Magnetic Stimulation on Seizure Frequency and Epileptiform Discharges in Drug-Resistant Epilepsy: A Meta-Analysis

Mishra A, Maiti R, Mishra BR, Jena M, Srinivasan A

BACKGROUND AND PURPOSE: The role of low-frequency repetitive transcranial stimulation (rTMS) in drug-resistant epilepsy (DRE) has been conflicting and inconclusive in previous clinical trials. This meta-analysis evaluated the efficacy of...
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Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus

Cho KO, Jeong KH, Cha JH, Kim SY

Regulator of calcineurin 1 (RCAN1) can be induced by an intracellular calcium increase and oxidative stress, which are characteristic features of temporal lobe epilepsy. Thus, we investigated the spatiotemporal expression...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Prognostic Factors for Absence Epilepsy in Childhood

Kang SY, Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary. We aimed to...
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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Prognostic Factors for Absence Epilepsy in Childhood

Kang SY, Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary. We aimed to...
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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends

Hong N

Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. Neuronal degeneration is irreversible process and it is proven to be...
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Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats

Kwon HH, Neupane C, Shin J, Gwon DH, Yin Y, Shin N, Shin HJ, Hong J, Park JB, Yi Y, Kim DW, Kang JW

Stress can induce a serious epileptic encephalopathy that occurs during early infancy. Recent studies have revealed that prenatal stress exposure is a risk factor for the development of infantile spasms....
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Distinct Topographical Patterns of Spike-Wave Discharge in Transgenic and Pharmacologically Induced Absence Seizure Models

Lee S, Hwang E, Lee M, Choi JH

Absence seizures (AS) are generalized non-convulsive seizures characterized by a brief loss of consciousness and spike-and-wave discharges (SWD) in an electroencephalogram (EEG). A number of animal models have been developed...
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Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine

Jung GH, You SJ

PURPOSE: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the...
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Effects of an Algorithm-based Education Program on Nursing Care for Children with Epilepsy by Hospital Nurses

Lee JH, Ju HO, Lee YJ

PURPOSE: Epilepsy is the most common neurological disorder in childhood. Hospital nurses, who are the first to recognize seizures in epilepsy patients in the ward environment, possess expertise related to...
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A POLG2 Homozygous Mutation in an Autosomal Recessive Epilepsy Family Without Ophthalmoplegia

Lee SJ, Kanwal S, Yoo DH, Park HR, Choi BO, Chung KW

No abstract available.
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Clinical Significance of Asymmetric Minimum Intensity Projection Images of Brain Magnetic Resonance Imaging in Children

Kim HS, Kim SJ, Kong YH

BACKGROUND AND PURPOSE: The susceptibility-weighted imaging form of brain MRI using minimum intensity projection (mIP) is useful for assessing traumatic brain injuries because it readily reveals deoxyhemoglobin or paramagnetic compounds....
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Clinical Usefulness of Intraoperative Motor-Evoked Potential Monitoring during Temporal Lobe Epilepsy Surgery

Koo DL, Lee WG, Hong SC, Seo DW

BACKGROUND AND PURPOSE: We aimed to determine the effectiveness of intraoperative neurophysiological monitoring focused on the transcranial motor-evoked potential (MEP) in patients with medically refractory temporal lobe epilepsy (TLE). METHODS: We...
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