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Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis

Meng RY, Li CS, Hu D, Kwon SG, Jin H, Chai OH, Lee JS, Kim SM

Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in esophageal...
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Letter to the Editor : Classifying the Anatomical Location of the Ureter after Retroperitoneal Dissection

Lee SH, Son DW, Lee JS, Song GS

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Korean guidelines for the management of gout

Lee JJ, Lee JS, Chung MK, Ahn JK, Choi HJ, Hong SJ, Yoon CH, Kim SH, Jeong KH, Kim JW, Kim BY, Shin JH, Kim WG, Kim SY, Kim HJ, Song JS, Jun JB, Park HA, Chae SC, Choi BS, Kim TN, Kim HA

Gout is the most common form of arthritis, with the prevalence increasing worldwide. The present treatment guidelines provide recommendations for the appropriate treatment of acute gout, management during the inter-critical...
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Glucose Regulation after Partial Pancreatectomy: A Comparison of Pancreaticoduodenectomy and Distal Pancreatectomy in the Short and Long Term

Lee JS, Sohn M, Kim K, Yoon YS, Lim S

Background: Long term quality of life is becoming increasingly crucial as survival following partial pancreatectomy rises. The purpose of this study was to investigate the difference in glucose dysregulation after...
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COVID-19 Pandemic-Related Job Loss Impacts on Mental Health in South Korea

Han KM, Lee SM, Hong M, Kim SJ, Sohn S, Choi YK, Hyun J, Kim H, Lee JS, Lee SH, Lee YR, Paik JW

Objective The economic hardship brought by the coronavirus disease-2019 (COVID-2019) pandemic has caused mental health problems among people of different socioeconomic status (SES). As social support helps to buffer these...
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Coexistence of Posterior Cortical Atrophy and Parkinson’s Disease

Ko EB, Hwang IJ, Kim JW, Jung DE, Lee JS, Yoo SW, Kim JS

We report a rare and unique presentation of a patient with early and levodopa-responsive Parkinson’s disease (PD) who exhibited clinical features similar to posterior cortical atrophy (PCA). The imaging evidence...
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Pigmented Fungiform Papillae of the Tongue: A Single-center Experience and Review of Literature

Lee J, Lee JS, Park SM, Shin K, Ko HC, Kim BS, Kim MB, Kim HS

Background: Pigmented fungiform papillae of the tongue (PFPT) is a rare benign pigmentary disorder of the tongue. In dark-skinned individuals, PFPT appears to be relatively common. However, limited data exist...
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Behavioral problems in Korean children and adolescents with atopic dermatitis

Park SH, Lee JS, Kim YH, Byeon JH, Yoon W, Yoo Y

Purpose Patients with atopic dermatitis (AD) experience a chronic relentless course which may affect emotional and behavioral problems. Moreover, AD could affect serious psychosocial problems due to its disfiguring skin conditions,...
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Full mouth rehabilitation of a patient with excessive worn dentition by increasing vertical dimension of occlusion: a case report

Lee JS, Shim JS, Ryu JJ

Tooth wear refers to the loss of dental hard tissue caused by various physiological and pathological causes, and excessive pathological wear can cause complications such as pathological changes in dimensions,...
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Neuroimaging Characteristics of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) in Korean Based on Jeju Cohort: A Pictorial Essay

Suh YR, Lee HK, Jung KH, Lee JS, Choi JC

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary small artery vasculopathy caused by mutations in the NOTCH3 gene on chromosome 19. Jeju Island has the...
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Korean guidelines for the management of gout

Lee JJ, Lee JS, Chung MK, Ahn JK, Choi HJ, Hong SJ, Yoon CH, Kim SH, Jeong KH, Kim JW, Kim BY, Shin JH, Kim WG, Kim SY, Kim HJ, Song JS, Jun JB, Park HA, Chae SC, Choi BS, Kim TN, Kim HA

Gout is the most common form of arthritis, with the prevalence increasing worldwide. The present treatment guidelines provide recommendations for the appropriate treatment of acute gout, management during the inter-critical...
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Risk Factors for the Occurrence and Severity of Vertebral Fractures in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Cohort Study

Choi A, Jung SH, Kim S, Lee JS

Background: The risk of vertebral fractures is increased in inflammatory bowel disease (IBD) patients. However, whether the severity of vertebral fractures differs between IBD patients and the general population, or...
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Definitions of Chronic Obstructive Pulmonary Disease and Chronic Obstructive Pulmonary Disease Exacerbation: A Modified Delphi Survey

Park YB, Lee JH, Ra SW, Park HY, Jung JY, Kang YA, Rhee CK, Kim DK, Yoo KH, Hwang YI, Lim SY, Lee JS, Jo KW, Oh YM

Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) update 2023 proposed new definitions of chronic obstructive pulmonary disease (COPD) and COPD exacerbation. However, an agreement on the definitions...
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Clinical features of enteric and colo-duodenal fistula in patients with Crohn’s disease

Lee JS, Kang SB, Park K, Yoon YS, Yu CS, Hwang SW, Ye BD, Yang SK, Lee JL, Park SH

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A novel etiological classification in patients with intracranial large vessel occlusion and endovascular treatment: discordance with the classic and SSS TOAST systems: A retrospective cohort study

Kim M, Lee SJ, Park SY, Hong JM, Lee JS

Purpose: Among patients with acute ischemic stroke (AIS), those with intracranial large vessel occlusion (LVO) should undertake endovascular treatment (EVT) based on mechanical thrombectomy. Although the Trial of Org 10172...
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Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion

Lee SH, Son DW, Bae SH, Lee JS, Kim YH, Sung SK, Lee SW, Song GS

Objective: Conventional oblique lumbar interbody fusion (OLIF) approach is possible from the L2/3 to L4/5 levels. However, obstruction of the lower ribs (10th–12th) makes it difficult to maintain disc parallel...
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MR Imaging Findings and Texture Analysis of Pure and Mixed Mucinous Breast Carcinoma

Song MW, Lim HS, Lee Hj, Park MH, Lee JS

Purpose: To evaluate the ability of magnetic resonance imaging (MRI) findings and texture features to differentiate between pure and mixed subtypes of mucinous breast carcinoma. Methods: This retrospective study included 136...
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Infection of the Cavernous Sinus Caused by Candida auris

Lee SH, Park SY, Lee JS, Oh J

Candida auris (C. auris) is a pathogen that causes severe infections, particularly in healthcare settings, and is resistant to common antifungal agents, leading to a global public health threat. Infections...
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Concomitant moyamoya syndrome and infratentorial arteriovenous malformation in a neurofibromatosis type 1 patient: a case report

Ko E, Hwang IJ, Kim JW, Lee JS, Jung DE, Yoo SW

Background: Neurofibromatosis type 1 (NF1) is a genetic disorder with diverse phenotypic manifestations. Cerebral vasculopathy is one of the multisystem involvements often overlooked unless symptomatic. Case Report: A 28-year-old male...
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Myelin oligodendrocyte glycoprotein antibody-associated disease manifesting as intractable fever managed by bromocriptine: a case report

Lee JS, Lee S, Oh Si

Background: Demyelinating events expressed as abnormal thermoregulatory responses are rare, but intractable fever in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is very rarely reported. Case Report: A 56-year-old woman presented with...
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