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Effects of Cannabidiol on Adaptive Behavior and Quality of Life in Pediatric Patients With Treatment-Resistant Epilepsy

Kim SH, Choi HS, Koo CM, Joo BR, Park BJ, Lee HK, Lee JS, Kim HD, Kang HC

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8-Methoxypsoralen Induces Apoptosis by Upregulating p53 and Inhibits Metastasis by Downregulating MMP-2 and MMP-9 in Human Gastric Cancer Cells

Choi EK, Kim HD, Park EJ, Song SY, Phan TT, Nam M, Kim M, Kim DU, Hoe KL

Furanocoumarin 8-methoxypsoralen (8-MOP) is the parent compound that naturally occurs in traditional medicinal plants used historically. 8-MOP has been employed as a photochemotherapeutic component of Psoralen + Ultraviolet A (PUVA)...
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Korean Practice Guidelines for Gastric Cancer 2022: An Evidence-based, Multidisciplinary Approach

Kim TH, Kim IH, Kang SJ, Choi M, Kim BH, Eom BW, Kim BJ, Min BH, Choi CI, Shin CM, Tae CH, Gong Cs, Kim DJ, Cho AEH, Gong EJ, Song GJ, Im HS, Ahn HS, Lim H, Kim HD, Kim JJ, Yu JI, Lee JW, Park JY, Kim JH, Song KD, Jung M, Jung MR, Son SY, Park SH, Kim SJ, Lee SH, Kim TY, Bae WK, Koom WS, Jee Y, Kim YM, Kwak Y, Park YS, Han HS, Nam SY, Kong SH, on behalf of The Development Working Group for the Korean Practice Guidelines for Gastric Cancer 2022 Task Force Team

Gastric cancer is one of the most common cancers in Korea and the world. Since 2004, this is the 4th gastric cancer guideline published in Korea which is the revised...
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Severity of post-COVID-19 organizing pneumonia in kidney transplant recipients according to SARS-CoV-2 vaccination

Choi S, Lee H, Kim HD, Ko EJ, Yang CW, Chung BH

Kidney transplant recipients (KTR) are on maintenance immunosuppression, therefore showed a higher risk for infection including coronavirus disease 2019 (COVID-19). In addition, the risk of progression to severe state of...
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Effects of Cannabidiol on Adaptive Behavior and Quality of Life in Pediatric Patients With Treatment-Resistant Epilepsy

Kim SH, Choi HS, Koo CM, Joo BR, Park BJ, Lee HK, Lee JS, Kim HD, Kang HC

Background and Purpose Data regarding the effects of cannabidiol (CBD) on the quality of life (QOL) are currently inadequate. We assessed the QOL of pediatric patients with epilepsy who were...
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Efficacy of the Ketogenic Diet for Pediatric Epilepsy According to the Presence of Detectable Somatic mTOR Pathway Mutations in the Brain

Ko A, Sim NS, Choi HS, Yang D, Kim SH, Lee JS, Kim DS, Lee JH, Kim HD, Kang HC

Background and Purpose A multifactorial antiepileptic mechanism underlies the ketogenic diet (KD), and one of the proposed mechanisms of action is that the KD inhibits the mammalian target of rapamycin...
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Idiopathic Retroperitoneal Hematoma with Spontaneous Resolution

Hwang YJ, Jin SJ, Jeong YJ, Myung HJ, Shin HY, Kim HD, Joo YE

A 54-year-old man was transferred from another hospital due to a hematoma in the third portion of the duodenum on abdomen CT. He had been admitted for 2 weeks due...
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Is It Appropriate to Insert Pedicle Screws at an Infected Vertebral Body in the Treatment of Lumbar Pyogenic Spondylodiscitis?

Na HY, Jung YH, Lee JY, Kim HD

Purpose: In the surgical treatment of pyogenic lumbar spondylodiscitis, screw insertion at the affected vertebra has been avoided because of biofilm formation, and the risk of infection recurrence. The authors...
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Intra-patient variability in tacrolimus trough levels over 2 years affects long-term allograft outcomes of kidney transplantation

Park Y, Lee H, Eum SH, Kim HD, Ko EJ, Yang CW, Chung BH

Background: The current study aimed to determine the impact of tacrolimus (TAC) trough level (C0) intra-patient variability (IPV) over 2 years after kidney transplantation (KT) on allograft outcomes. Methods: In total,...
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Prognostic Stratification of Patients with Burkitt Lymphoma Using Serum β2-microglobulin Levels

Kim HD, Cho H, Kim S, Lee K, Kang EH, Park JS, Park CS, Huh J, Ryu JS, Lee SW, Yoon DH, Kim SJ, Ko YH, Kim WS, Suh C

Purpose We aimed to investigate the prognostic value of serum β2-microglobulin for patients with Burkitt lymphoma (BL) and to propose a risk-stratifying classification system. Materials and Methods A prospective registry-based cohort...
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A Rare Case of Pulmonary Arteriovenous Malformation Caused by Hereditary Hemorrhagic Telangiectasia in a Hemodialysis Patient

Bahk S, Bu SH, Kim HD, Won Y, Lee HG, Kim YO

Hereditary hemorrhagic telangiectasia (HHT) is an uncommon autosomal dominant disorder resulting in vascular malformation, such as pulmonary arteriovenous malformation (PAVM). Here, we report a rare case of pulmonary arteriovenous malformation...
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Clinical Features and Treatment Outcomes of Seronegative Pediatric Autoimmune Encephalitis

Lee S, Kim HD, Lee JS, Kang HC, Kim SH

Background and Purpose New diagnostic criteria for pediatric autoimmune encephalitis (AIE) have been introduced recently. A substantial proportion of cases of pediatric AIE are diagnosed as seronegative based on these...
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Smoking and Drinking Adjusted Association between Head and Neck Cancers and Oral Health Status Related to Periodontitis: a Meta-Analysis

Vu H, Shin YJ, Kong MS, Kim HD

Background: Not so many reports about the association between head and neck cancer (HNC) and oral health status related to periodontitis (OHS-P) has been published in different countries with different...
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Employment Status Change and New-Onset Depressive Symptoms in Permanent Waged Workers

Kim HD, Park SG

Background: This study aimed to investigate the relationship between changes in employment status and new-onset depressive symptoms through a one-year follow-up of permanent waged workers. Methods: We analyzed the open-source data...
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Mortality prediction of serum neutrophil gelatinase-associated lipocalin in patients requiring continuous renal replacement therapy

Park Y, Ban TH, Kim HD, Ko EJ, Lee J, Kim SC, Park CW, Yang CW, Kim YS, Chung BH

Background/Aims: We investigated whether serum neutrophil gelatinase-associated lipocalin (NGAL) can predict mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). Methods: This study enrolled 169 patients...
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Screening of Tuberous Sclerosis-Associated Neuropsychiatric Disorders in Korea Using the TAND Checklist

Park S, Eom S, Kang HC, Lee JS, Kim HD, Chung HJ

Purpose: The present study aimed to elucidate the clinical characteristics of children with tuberous sclerosis complex (TSC) in Korea using the Tuberous Sclerosis-Associated Neuropsychiatric Disorders (TAND) checklist to evaluate the...
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Spatial Distribution and Prognostic Implications of Tumor-Infiltrating FoxP3- CD4+ T Cells in Biliary Tract Cancer

Kim HD, Kim JH, Ryu YM, Kim D, Lee S, Shin J, Hong SM, Kim KH, Jung D, Song G, Hwang DW, Lee JH, Song KB, Ryoo BY, Jeong JH, Kim Kp, Kim SY, Yoo C

Purpose The clinical implications of tumor-infiltrating T cell subsets and their spatial distribution in biliary tract cancer (BTC) patients treated with gemcitabine plus cisplatin were investigated. Materials and Methods A total of 52...
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Cannabidiol for Treating LennoxGastaut Syndrome and Dravet Syndrome in Korea

Koo CM, Kim SH, Lee JS, Park BJ, Lee HK, Kim HD, Kang HC

Background: For the first time in Korea, we aimed to study the efficacy and safety of cannabidiol (CBD), which is emerging as a new alternative in treating epileptic encephalopathies. Methods: This...
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Changes of T lymphocyte subsets after kidney transplantation according to induction immunosuppressants

Kim HD, Bae H, Yang CW, Oh EJ, Chung BH

Background: The aim of this study is to investigate the change of T cell subsets during early post-transplant period according to the type of induction therapy (anti-thymocyte globulin [ATG] vs....
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Clinical outcomes of infection-related hospitalization in incident peritoneal dialysis patients

Jeon Y, Kim HD, Hong YA, Kim HW, Yang CW, Chang YK, Kim YK

Background: Infection is the second leading cause of death in patients undergoing long-term dialysis. Peritoneal dialysis (PD) is associated with an increased risk of infection-related hospitalization (IRH) when compared with...
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