- Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
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Cho KO, Jeong KH, Cha JH, Kim SY
- KMID: 2466572
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):81-88.
- doi: 10.4196/kjpp.2020.24.1.81
Regulator of calcineurin 1 (RCAN1) can be induced by an intracellular calcium increase and oxidative stress, which are characteristic features of temporal lobe epilepsy. Thus, we investigated the spatiotemporal expression... -
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- Clinical Usefulness of Intraoperative Motor-Evoked Potential Monitoring during Temporal Lobe Epilepsy Surgery
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Koo DL, Lee WG, Hong SC, Seo DW
- KMID: 2451110
- J Clin Neurol.
- 2019 Jul;15(3):285-291.
- doi: 10.3988/jcn.2019.15.3.285
BACKGROUND AND PURPOSE: We aimed to determine the effectiveness of intraoperative neurophysiological monitoring focused on the transcranial motor-evoked potential (MEP) in patients with medically refractory temporal lobe epilepsy (TLE). METHODS: We... -
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- Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpine-induced status epilepticus in mice
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Cho KO, Kim JY, Jeong KH, Lee MY, Kim SY
- KMID: 2450495
- Korean J Physiol Pharmacol.
- 2019 Jul;23(4):281-289.
- doi: 10.4196/kjpp.2019.23.4.281
Vascular endothelial growth factor (VEGF)-C and its receptor, vascular endothelial growth factor receptor (VEGFR)-3, are responsible for lymphangiogenesis in both embryos and adults. In epilepsy, the expression of VEGF-C and... -
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- A Primer on Magnetic Resonance-Guided Laser Interstitial Thermal Therapy for Medically Refractory Epilepsy
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Lee EJ, Kalia SK, Hong SH
- KMID: 2453241
- J Korean Neurosurg Soc.
- 2019 May;62(3):353-360.
- doi: 10.3340/jkns.2019.0105
Epilepsy surgery that eliminates the epileptogenic focus or disconnects the epileptic network has the potential to significantly improve seizure control in patients with medically intractable epilepsy. Magnetic resonance-guided laser interstitial... -
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- Antiepileptic and anti-neuroinflammatory effects of red ginseng in an intrahippocampal kainic acid model of temporal lobe epilepsy demonstrated by electroencephalography
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Kim JY, Kim JH, Lee HJ, Kim SH, Jung YJ, Lee HY, Kim HJ, Kim SY
- KMID: 2433738
- Yeungnam Univ J Med.
- 2018 Dec;35(2):192-198.
- doi: 10.12701/yujm.2018.35.2.192
BACKGROUND: Chronic inflammation can lower the seizure threshold and have influence on epileptogenesis. The components of red ginseng (RG) have anti-inflammatory effects. The abundance of peripherally derived immune cells in... -
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- A Novel Nonsense Mutation in Leucine-Rich, Glioma-Inactivated-1 Gene as the Underlying Cause of Familial Temporal Lobe Epilepsy
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Kanwal S, Yoo DH, Tahir S, Lee SJ, Lee MH, Choi BO, Chung KW
- KMID: 2424194
- J Clin Neurol.
- 2018 Oct;14(4):591-593.
- doi: 10.3988/jcn.2018.14.4.591
No abstract available. -
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- Morin Prevents Granule Cell Dispersion and Neurotoxicity via Suppression of mTORC1 in a Kainic Acid-induced Seizure Model
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Lee JM, Hong J, Moon GJ, Jung UJ, Won SY, Kim SR
- KMID: 2416250
- Exp Neurobiol.
- 2018 Jun;27(3):226-237.
- doi: 10.5607/en.2018.27.3.226
An abnormal reorganization of the dentate gyrus and neurotoxic events are important phenotypes in the hippocampus of patients with temporal lobe epilepsy (TLE). The effects of morin, a bioflavonoid constituent... -
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- A Case of Phantosmia Occurred by Glioblastoma
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Lee SY, Kim JW
- KMID: 2412921
- J Rhinol.
- 2018 May;25(1):47-50.
- doi: 10.18787/jr.2018.25.1.47
Phantosmia is defined as the false perception of odors without any environmental odor stimulus. It is a very rare phenomenon, but it can be caused by a wide variety of... -
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- Structural and Functional Alterations at Pre-Epileptic Stage Are Closely Associated with Epileptogenesis in Pilocarpine-induced Epilepsy Model
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Kim H, Choi Y, Joung HY, Choi YS, Kim HJ, Joo Y, Oh JH, Hann HJ, Cho ZH, Lee HW
- KMID: 2398433
- Exp Neurobiol.
- 2017 Oct;26(5):287-294.
- doi: 10.5607/en.2017.26.5.287
Pilocarpine-induced rat epilepsy model is an established animal model that mimics medial temporal lobe epilepsy in humans. The purpose of this study was to investigate neuroimaging abnormalities in various stages... -
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- Beneficial Effects of Silibinin Against Kainic Acid-induced Neurotoxicity in the Hippocampus in vivo
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Kim S, Jung UJ, Oh YS, Jeon MT, Kim HJ, Shin WH, Hong J, Kim SR
- KMID: 2398431
- Exp Neurobiol.
- 2017 Oct;26(5):266-277.
- doi: 10.5607/en.2017.26.5.266
Silibinin, an active constituent of silymarin extracted from milk thistle, has been previously reported to confer protection to the adult brain against neurodegeneration. However, its effects against epileptic seizures have... -
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- Ictal sinus pause and myoclonic seizure in a child
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Kim HR, Kim GH, Eun SH, Eun BL, Byeon JH
- KMID: 2362274
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S129-S132.
- doi: 10.3345/kjp.2016.59.11.S129
Ictal tachycardia and bradycardia are common arrhythmias; however, ictal sinus pause and asystole are rare. Ictal arrhythmia is mostly reported in adults with temporal lobe epilepsy. Recently, ictal arrhythmia was... -
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- Asymmetric Gray Matter Volume Changes Associated with Epilepsy Duration and Seizure Frequency in Temporal-Lobe-Epilepsy Patients with Favorable Surgical Outcome
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Kim JS, Koo DL, Joo EY, Kim ST, Seo DW, Hong SB
- KMID: 2354120
- J Clin Neurol.
- 2016 Jul;12(3):323-331.
- doi: 10.3988/jcn.2016.12.3.323
BACKGROUND AND PURPOSE: This study aimed to estimate the changes in gray matter volume (GMV) and their hemispheric difference in patients with mesial temporal lobe epilepsy (MTLE) using a voxel-based... -
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- Changes in Central Auditory Processing in Patients with Mesial Temporal Lobe Epilepsy after Anterior Temporal Lobectomy with Amygdalohippocampectomy
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Han SH, Lee EM, Choi EJ, Ryu HU, Kang JK, Chung JW
- KMID: 2354134
- J Clin Neurol.
- 2016 Apr;12(2):151-159.
- doi: 10.3988/jcn.2016.12.2.151
BACKGROUND AND PURPOSE: This study aimed to determine the effects of anterior temporal lobectomy with amygdalohippocampectomy (ATL-AH) on central auditory processing (CAP) in patients with mesial temporal lobe epilepsy with... -
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- Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
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Park HR, Chung HT, Lee SK, Kim DG, Paek SH
- KMID: 2352879
- Exp Neurobiol.
- 2016 Apr;25(2):93-101.
- doi: 10.5607/en.2016.25.2.93
An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS... -
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- Modulation of axonal sprouting along rostro-caudal axis of dorsal hippocampus and no neuronal survival in parahippocampal cortices by long-term post-lesion melatonin administration in lithium-pilocarpine model of temporal lobe epilepsy
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Kazemi M, Shokri S, Ganjkhani , Ali R, Iraj JA
- KMID: 2308929
- Anat Cell Biol.
- 2016 Mar;49(1):21-33.
- doi: 10.5115/acb.2016.49.1.21
Feature outcome of hippocampus and extra-hippocampal cortices was evaluated in melatonin treated lithium-pilocarpine epileptic rats during early and chronic phases of temporal lobe epilepsy (TLE). After status epilepticus (SE) induction,... -
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- EEG Source Imaging in Partial Epilepsy in Comparison with Presurgical Evaluation and Magnetoencephalography
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Park CJ, Seo JH, Kim D, Abibullaev B, Kwon H, Lee YH, Kim MY, An KM, Kim K, Kim JS, Joo EY, Hong SB
- KMID: 2179751
- J Clin Neurol.
- 2015 Oct;11(4):319-330.
- doi: 10.3988/jcn.2015.11.4.319
BACKGROUND AND PURPOSE: The aim of this study was to determine the usefulness of three-dimensional (3D) scalp EEG source imaging (ESI) in partial epilepsy in comparison with the results of... -
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- Preserved Hippocampal Glucose Metabolism on 18F-FDG PET after Transplantation of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells in Chronic Epileptic Rats
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Park GY, Lee EM, Seo MS, Seo YJ, Oh JS, Son WC, Kim KS, Kim JS, Kang JK, Kang KS
- KMID: 2344146
- J Korean Med Sci.
- 2015 Sep;30(9):1232-1240.
- doi: 10.3346/jkms.2015.30.9.1232
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) may be a promising modality for treating medial temporal lobe epilepsy. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a noninvasive method for monitoring... -
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- Psychiatric Symptoms in Temporal Lobe Epilepsy with Left Mesial Hippocampal Sclerosis
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Jang H, Kim SH, Park SH, Choo IH, Kim SG
- KMID: 2316440
- Psychiatry Investig.
- 2015 Apr;12(2):274-277.
- doi: 10.4306/pi.2015.12.2.274
A 16-year-old woman was referred to us for depression and persistent suicidal and homicidal ideation. From 2010, the patient visited a neurologist due to recurrent grand mal epilepsy, auditory and... -
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- Temporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes
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Lee YJ, Lee JS
- KMID: 2284253
- Korean J Pediatr.
- 2013 Jul;56(7):275-281.
- doi: 10.3345/kjp.2013.56.7.275
Temporal lobe epilepsy (TLE) is the most common type of medically intractable epilepsy in adults and children, and mesial temporal sclerosis is the most common underlying cause of TLE. Unlike... -
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- Oxcarbazepine Induced Leukopenia
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Son YR, Kim YS, Chu K, Lee SK
- KMID: 1431584
- J Korean Epilepsy Soc.
- 2013 Jun;17(1):22-23.
Oxcarbazepine (OXC) is generally assumed to be safe with regard to the risk for adverse hematopoietic effects. Recently, pancytopenia and leukopenia associated with the treatment of OXC have been reported.... -
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