J Korean Assoc Oral Maxillofac Surg.  2013 Apr;39(2):43-54. 10.5125/jkaoms.2013.39.2.43.

Antimicrobial surfaces for craniofacial implants: state of the art

Affiliations
  • 1Department of Biomedical Engineering, University of Texas at San Antonio, San Antonio, TX, USA. anson.ong@utsa.edu

Abstract

In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rates, osseointegration and antibacterial properties are often hard to achieve. Although bone-implant interactions are highly dependent on the implant's surface characteristics, infections following traumatic craniofacial injuries are common. As such, poor osseointegration and infections are two of the many causes of implant failure. Further, as increasingly complex dental repairs are attempted, the likelihood of infection in these implants has also been on the rise. For these reasons, the treatment of craniofacial bone defects and dental repairs for long-term success remains a challenge. Various approaches to reduce the rate of infection and improve osseointegration have been investigated. Furthermore, recent and planned tissue engineering developments are aimed at improving the implants' physical and biological properties by improving their surfaces in order to develop craniofacial bone substitutes that will restore, maintain and improve tissue function. In this review, the commonly used biomaterials for craniofacial bone restoration and dental repair, as well as surface modification techniques, antibacterial surfaces and coatings are discussed.

Keyword

Dental implants; Osseointegration; Antimicrobial agents; Surface-coated materials; Bone regeneration

MeSH Terms

Anti-Infective Agents
Biocompatible Materials
Bone Regeneration
Bone Substitutes
Coated Materials, Biocompatible
Dental Implants
Durapatite
Esthetics
Osseointegration
Polymers
Tissue Engineering
Titanium
Anti-Infective Agents
Biocompatible Materials
Bone Substitutes
Coated Materials, Biocompatible
Dental Implants
Durapatite
Polymers
Titanium
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