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Decellularized Non-cross-linked Collagen Membranes for Guided Bone Regeneration in Rabbit Calvarial Defects

Jeon SH, Lee DN, Seo YW, Park JY, Paik JW, Cha JK, Choi SH

Purpose: The aim of this study was to evaluate the bio-durability and bone regeneration capacity of the non-crosslinked collagen membrane in rabbit calvarial defect models. Materials and Methods: Four circular defects...
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Membrane Fixation using Healing Abutment during Guided Bone Regeneration: A Report of Two Cases

Kwon TK, Kang YHK, Byun JH

Guided bone regeneration, a dental surgical procedure, is used to promote growth of the alveolar hard tissue for bone defect with the help of membranes and other barrier techniques. The...
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Comparative effects of systemic administration of levofloxacin and cephalexin on fracture healing in rats

Golestani S, Golestaneh A, Gohari AA

Objectives: This study aimed to compare the effects of systemic administration of levofloxacin or cephalexin on fracture healing in rats. Materials and Methods: In this animal study, tibial fractures not requiring...
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Use of stem cells in bone regeneration in cleft palate patients: review and recommendations

Amiri MA, Lavaee F, Danesteh H

This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation...
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Effects of Induction Culture on Osteogenesis of Scaffold-Free Engineered Tissue for Bone Regeneration Applications

Park HM, Kim SH, Choi BH, Park SH

BACKGROUND: Restoration of the bone defects caused by infection or disease remains a challenge in orthopedic surgery. In recent studies, scaffold-free engineered tissue with a self-secreted extracellular matrix has been...
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Maxillary sinus floor augmentation using two different ratios of cancellous and cortical freeze-dried bone allograft mixtures: clinical and histological outcomes

Yang KI, Ji CS, Cho OH, Yun HJ, Lee WP, Kim BO, Yu SJ

The aim of this study was to evaluate the clinical and histologic outcomes of sinus floor augmentation using mixtures of cancellous and cortical freeze-dried bone allograft (AG) at two different...
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Role of prolyl hydroxylase domain proteins in bone metabolism

Wolf D, Muralidharan A, Mohan S

Cellular metabolism requires dissolved oxygen gas. Because evolutionary refinements have constrained mammalian dissolved oxygen levels, intracellular oxygen sensors are vital for optimizing the bioenergetic and biosynthetic use of dissolved oxygen....
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Synergistic Effect of Whitlockite Scaffolds Combined with Alendronate to Promote Bone Regeneration

Jeong J, Shim JH, Koo BM, Choy YB, Heo CY

BACKGROUND: Due to the increasing aging of society, the number of patients suffering from senile diseases is increasing. Patients suffering from osteoporosis, which is a representative senile disease, take a...
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The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model

Assefa F, Kim JA, Lim J, Nam SH, Shin HI, Park EK

BACKGROUND: The neural regulation of bone regeneration has emerged recently. Spexin (SPX) is a novel neuropeptide and regulates multiple biological functions. However, the effects of SPX on osteogenic differentiation need...
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Regenerative procedure using rotary titanium brush for surface decontamination of peri-implantitis: 3 cases with a 2-year follow-up

Baek MW, Yu JA, Choi SH, Lee DW

Peri-implantitis, in which inflammation caused by plaque and biofilm on the implant surface spreads to the hard tissue, can be treated by decontamination of the implant surface and reconstruction of...
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Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw

Esen A, Gurses G, Akkulah S

Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we...
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Evaluation of bone regeneration ability of Mg mesh coated with calcium phosphate by cyclic precalcification treatment

Park JE, Kim SY, Ji JH, Jang YS, Jeon WY, Lee MH, Bae TS

Surface treatment was conducted to reduce dissolution of Mg mesh and to improve bioactivity in physiological environment. Mg mesh was immersed in 40 wt% hydrofluoric (HF) solution for 2 hours...
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Titanium Mesh for Bone Augmentation in Oral Implant Surgery

Chee Y

Bone augmentation should be performed to recover a sufficient amount of bone before implant placement at the site where a bone defect occurs due to bone resorption caused by tooth...
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Use of Porcine-derived Block Bone Substitutes for Guided Bone Regeneration in the Peri-implant Dehiscence Defects of the Mandibular Anterior Region

Lee JH, Jeong SN

Purpose: Various bone graf t materials are currently used for guided bone regeneration (GBR), but data are lacking on the superiority of one biomaterial relative to the other. In addition,...
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Effect of Human Umbilical Cord Matrix-Derived Mesenchymal Stem Cells on Bisphosphonate-Related Osteonecrosis of the Jaw

Yang G, Kim YN, Kim H, Lee BK

BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe sequela caused by bisphosphonates (BPs), which are widely used to treat osteoporosis or other malignancies. However, the mechanism underlying BRONJ...
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Three-Dimensional Computed Tomography Follow-Up on Spontaneous Bone Healing after Excision of Periorbital Dermoid Cyst: A Case Report

Park H, Seong J, Park H, Yeo H

Dermoid cysts are among the most common periorbital and orbital tumors presenting in childhood. Several studies have shown that dermoid cysts may deform adjacent bones; however, few studies have followed...
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The Combination of Concentrated Growth Factor and AdiposeDerived Stem Cell Sheet Repairs Skull Defects in Rats

Hu T, Zhang H, Yu W, Yu X, Li Z, He L

BACKGROUND: The goal of this study was to create a biomaterial which combines concentrated growth factor (CGF) with an adipose-derived stem cell (ADSC) sheet to promote the repair of skull...
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The Measurement of Dimensional Ridge Contour Changes after Tooth Extraction Using Intraoral Scanner: A Clinical Pilot Study

Kim YJ, Lee MY, Kim JH, Park JM, Ku Y

Purpose: This study aimed to identif y the trend of horizontal sof t tissue contour changes in extraction sockets using data obtained by intraoral scanners, and to investigate the effect...
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Degradation Properties of a Bi-layered Crosslinked Collagen Membrane for Localized Bone Regeneration: In Vitro and In Vivo Study

Park JY, Lee JH, Cha JK, Lee JS, Jung UW, Choi SH

Purpose: (i) To evaluate the biologic properties of a bi-layered 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride-cross-linked collagen membrane (CCM) In Vitro. (ii) To assess the efficacy of CCM for localized bone regeneration In Vivo. Materials...
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The Sausage Technique using Collagen Membrane without Autogenous Bone Graft: A Case Report

Lee SJ

Various techniques have been introduced for the guided bone regeneration procedure. Among these, the sausage technique using a natural collagen membrane has many advantages. This report describes two cases wherein...
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