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Bioactivity of endodontic biomaterials on dental pulp stem cells through dentin

Javid B, Panahandeh N, Torabzadeh H, Nazarian H, Parhizkar , Asgary S

OBJECTIVES: This study investigated the indirect effect of calcium-enriched mixture (CEM) cement and mineral trioxide aggregate (MTA), as 2 calcium silicate-based hydraulic cements, on human dental pulp stem cells (hDPSCs)...
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3D architecture developments for spatial controls of periodontal ligament regeneration with angular orientations

Park CH

Various biomaterial-based, 3D architectures with micron-scaled geometries have been investigated for periodontal tissue neogenesis, and appropriate fabrication techniques for the scaffold manufacturing have been developed for pre-clinical or clinical situations....
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Total Hip Arthroplasty: Past, Present, and Future. What Has Been Achieved?

Shon WY, Park BY, R RN, Park PS, Im JT, Yun HH

In the 1960s, Sir John Charnley introduced to clinical practice his concept of low-friction total hip arthroplasty (THA). Although early designs were plagued by poor performance and even failure, there...
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Biomaterials for the Treatment of Tendon Injury

Kim SE, Kim JG, Park K

BACKGROUND: Most tendon injuries are occurring from a gradual wearing and tearing of the tendon tissues from overuse. Such injuries are usually seen in sports, exercising, or daily activities that...
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Comparative preclinical assessment of the use of dehydrated human amnion/chorion membrane to repair perforated sinus membranes

Chang YY, Kim SH, Goh MS, Yun JH

PURPOSE: The aim of this study was to evaluate the use of dehydrated human amnion/chorion membrane (dHACM) to repair perforated sinus membranes in rabbits. METHODS: Bilateral surgical windows (7.5-mm diameter) were...
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The Clinical Uses of Collagen-Based Matrices in the Treatment of Chronic Wounds

Yang HJ, Kang SY

Chronic wounds are defined as wounds that fail to heal completely at the pace and order observed in normal phases of wound healing. Whereas acute wounds proceed through the normal...
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Three-dimensional Printed Mg-Doped b-TCP Bone Tissue Engineering Scaffolds: Effects of Magnesium Ion Concentration on Osteogenesis and Angiogenesis In Vitro

Gu Y, Zhang J, Zhang X, Liang G, Xu T, Niu W

BACKGROUND: Three-dimensional (3D) printed bone tissue engineering scaffolds have been widely used in research and clinical applications. β-TCP is a biomaterial commonly used in bone tissue engineering to treat bone...
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Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Venkatesan JK, Rey-Rico A, Cucchiarini M

BACKGROUND: Viral vector-based therapeutic gene therapy is a potent strategy to enhance the intrinsic reparative abilities of human orthopaedic tissues. However, clinical application of viral gene transfer remains hindered by...
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Decontamination methods to restore the biocompatibility of contaminated titanium surfaces

Jin SH, Lee EM, Park JB, Kim KK, Ko Y

PURPOSE: The reaction of cells to a titanium implant depends on the surface characteristics of the implant which are affected by decontamination. The aim of this study was to evaluate...
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Biocompatibility of n-butyl-2-cyanoacrylate (Histoacryl) in cervical structures of rats: prospective in vivo study

Suh YJ, Yu HW, Kim SJ, Choe JY, Park HJ, Choi JY, Lee KE

PURPOSE: We investigated the biocompatibility of n-butyl-2-cyanoacrylate (NBCA) in the cervical deep tissues of rats to assess its biocompatibility. METHODS: A total of 30 Sprague-Dawley rats were injected with NBCA. After...
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Generation of novel hyaluronic acid biomaterials for study of pain in third molar intervention: a review

Shuborna N, Chaiyasamut T, Sakdajeyont W, Vorakulpipat C, Rojvanakarn M, Wongsirichat N

Hyaluronic acid (HA) has long been studied in diverse applications. It is a naturally occurring linear polysaccharide in a family of unbranched glycosaminoglycans, which consists of repeating di-saccharide units of...
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Apoptotic Cell-Mimetic Polymers for Anti-Inflammatory Therapy

Ebara M

The field of biomaterials has seen a strong rejuvenation due to the new potential to modulate immune system in our body. This special class of materials is called “immunomodulatory biomaterials”....
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A Comparison of the Effects of Silica and Hydroxyapatite Nanoparticles on Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/Chitosan Nanofibrous Scaffolds for Bone Tissue Engineering

Raeisdasteh Hokmabad V, Davaran S, Aghazadeh , Alizadeh E, Salehi R, Ramazani A

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(ε-caprolactone)-poly(ethylene...
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Effectiveness of Polyvinyl Acetate Sheeted with Carboxymethyl Cellulose as a Packing Material after Septoplasty

Kim SD, Kim D, Kim DS, Kim JA, Lee DJ, Cho KS

BACKGROUND AND OBJECTIVES: Although polyvinyl acetate (Merocel®) has been widely used as a packing material after septoplasty, removable nasal packing can increase patient discomfort, local pain, and pressure. Furthermore, the...
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Cardiac Regeneration with Human Pluripotent Stem Cell-Derived Cardiomyocytes

Park M, Yoon YS

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which are collectively called pluripotent stem cells (PSCs), have emerged as a promising source for regenerative medicine. Particularly, human pluripotent...
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Sensory and Motor Behavior Evidences Supporting the Usefulness of Conditioned Medium from Dental Pulp-Derived Stem Cells in Spinal Cord Injury in Rats

Asadi-Golshan R, Razban V, Mirzaei E, Rahmanian , Khajeh S, Mostafavi-Pour Z, Dehghani F

STUDY DESIGN: Experimental animal study. PURPOSE: This study aimed to assess effects of conditioned medium (CM) of dental pulp-derived stem cells loaded in collagen hydrogel on functional recovery following spinal cord...
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Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status

Cho KH, Uthaman S, Park IK, Cho CS

BACKGROUND: Injectable biomaterials have attracted increasing attention for volume restoration and tissue regeneration. The main aim of this review is to discuss the current status of the injectable biomaterials for...
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In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative Medicine

Park KM, Park KD

BACKGROUND: Polymeric hydrogels are extensively used as promising biomaterials in a broad range of biomedical applications, including tissue engineering, regenerative medicine, and drug delivery. These materials have advantages such as...
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Click Chemistry-Based Injectable Hydrogels and Bioprinting Inks for Tissue Engineering Applications

Gopinathan J, Noh I

BACKGROUND: The tissue engineering and regenerative medicine approach require biomaterials which are biocompatible, easily reproducible in less time, biodegradable and should be able to generate complex three-dimensional (3D) structures to...
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Alveolar ridge preservation with a collagen material: a randomized controlled trial

Schnutenhaus S, Doering I, Dreyhaupt , Rudolph H, Luthardt R

PURPOSE: Resorption of the alveolar bone is an unavoidable consequence of tooth extraction when appropriate alveolar ridge preservation (ARP) measures are not taken. The objective of this trial was to...
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