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3D-culture models as drug-testing platforms in canine lymphoma and their cross talk with lymph nodederived stromal cells

An JH, Song WJ, Li Q, Bhang DH, Youn HY

Background: Malignant lymphoma is the most common hematopoietic malignancy in dogs, and relapse is frequently seen despite aggressive initial treatment. In order for the treatment of these recurrent lymphomas in...
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Feline adipose tissue-derived mesenchymal stem cells pretreated with IFN-γ enhance immunomodulatory effects through the PGE 2 pathway

Park SG, An JH, Li Q, Chae HK, Park SM, Lee JH, Ahn JO, Song WJ, Youn HY

Background: Preconditioning with inflammatory stimuli is used to improve the secretion of anti-inflammatory agents in stem cells from variant species such as mouse, human, and dog. However, there are only...
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Impact of the Preoperative Neutrophil to Lymphocyte Ratio on Patients with Head and Neck Cancer

Kim GJ, Kang JM, Seo JH, Hwang SH, Youn HY, Jin HJ, Kang HR, Lee HH, Joo YH

Background and Objectives To investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) in patients with head and neck squamous cell cancer (HNSCC). Subjects and Method Clinical data from...
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A retrospective study of theophylline-based therapy with tracheal collapse in small-breed dogs: 47 cases (2013–2017)

Jeung SY, Sohn SJ, An JH, Chae HK, Li Q, Choi M, Yoon J, Song WJ, Youn HY

Theophylline acts as a bronchodilator and has an anti-inflammatory effect. In addition, theophylline can be applied in patients where there are concerns regarding the side-effects of corticosteroids. This retrospective case...
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Association of Sleep Duration and Depression with Periodontitis in Older People Aged 65 Years and Older

Youn HY, Shin HE, Cho MJ

BACKGROUND: Sleep disorder is a precursor to depression, which is one of the psychological factors associated with periodontal disease that, in turn, affects general and periodontal health. This study aimed...
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Erratum: A retrospective study of theophylline-based therapy with tracheal collapse in small-breed dogs: 47 cases (2013–2017)

Jeung SY, Sohn SJ, An JH, Chae HK, Li Q, Choi M, Yoon J, Song WJ, Youn HY

The authors regret that there were errors in funding section.
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Can the number of functional teeth potentially affect cognitive function?

Cho MJ, Kim JY, Jung YS, Shin HE, Youn HY, Park TJ, Choi YH, Song KB

OBJECTIVES: With the growing elderly population, there is an increasing interest in the oral and general health of elderly individuals. Loss of teeth is representative of oral disease in elderly...
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Analysis of Relationship between Reflux Symptom Index and Psychiatric Problems

Park IJ, Kang JM, Seo JH, Hwang SH, Youn HY, Jin HJ, Kang HR, Joo YH

BACKGROUND AND OBJECTIVES: This study investigated the relationship between reflux symptom index (RSI) and psychiatric problems such as depression, somatization, and anxiety. SUBJECTS AND METHOD: We prospectively analyzed 231 patients with...
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Retrospective study of degenerative mitral valve disease in small-breed dogs: survival and prognostic variables

Kim HT, Han SM, Song WJ, Kim B, Choi M, Yoon J, Youn HY

Small-breed dogs (n = 168; weight < 15 kg) diagnosed with myxomatous mitral valve degeneration based on a routine clinical examination, radiology, electrocardiography, and echocardiography at the Seoul National University...
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Fulminant multicentric osteosarcoma with systemic metastasis in a dog

Lee JH, Go DM, Lee SH, Lee GG, Choi MC, Youn HY, Kim DY

A 15-year-old castrated mixed breed dog presented due to a 5-month history of cough and difficulty in ambulation. Necropsy showed multiple periosteal and intramedullary infiltrative masses in the appendicular skeleton....
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Relationship between the Subjective-Objective Oral Health Status and Oral Health Related Quality of Life in the Elderly

Youn HY, Cho MJ, Hwang YS, Koh KW

The purpose of this study was to analyze the relationship between objective oral health status determined by dentists, self-perceived subjective oral health status, and oral health related quality of life...
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Hyperammonemic hepatic encephalopathy management through L-ornithin-L-aspartate administration in dogs

Ahn JO, Li Q, Lee YH, Han SM, Hwang CY, Youn HY, Chung JY

Seventeen dogs were treated with L-ornithin-L-aspartate (LOLA; experimental group). Three dogs were treated with lactulose recognized therapy (control group). Following LOLA administration, 15 dogs experienced a significant decrease in ammonia...
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Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats

Kim HW, Song WJ, Li Q, Han SM, Jeon KO, Park SC, Ryu MO, Chae HK, Kyeong K, Youn HY

Severe acute pancreatitis (SAP) is associated with systemic complications and high mortality rate in dogs. Mesenchymal stem cells (MSCs) have been investigated for their therapeutic potential in several inflammation models....
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Guidelines for vaccination of dogs and cats in Korea

Song WJ, Kim HT, Yoo HS, Youn HY

This guideline contains the recommended vaccination schedules of dogs and cats from World Small Animal Veterinary Association (WSAVA) and American Animal Hospital Association (AAHA). In 2010, WSAVA published guidelines for...
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Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells

Han SM, Han SH, Coh YR, Jang G, Chan Ra J, Kang SK, Lee HW, Youn HY

Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency and self-renewal, are naturally expressed...
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Use of laparoscopy for diagnosing experimentally induced acute pancreatitis in dogs

Kim HW, Oh YI, Choi JH, Kim DY, Youn HY

Diagnosis of acute pancreatitis in dogs remains a significant challenge despite the development of advanced diagnostic methodologies. Visual inspection and pancreas biopsy using laparoscopy are generally considered to be procedures...
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An Autochthonous Case of Canine Visceral Leishmaniasis in Korea

Bhang DH, Choi US, Kim HJ, Cho KO, Shin SS, Youn HJ, Hwang CY, Youn HY

  • KMID: 1792146
  • Korean J Parasitol.
  • 2013 Oct;51(5):545-549.
A 12-year-old spayed female mixed-bred dog presented with nasal bleeding of 2 days duration and a skin nodule in the left flank. No abnormalities were found in coagulation profiles and...
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Effects of 5-HT4 selective receptor agonist, mosapride citrate on electrocardiogram in dogs

Chae JS, Ahn JO, Coh YR, Park CW, Youn HY

  • KMID: 1435829
  • Korean J Vet Res.
  • 2012 Sep;52(3):163-167.
Mosapride stimulated dietary motility was introduced because of the arrhythmogenic effect of cisapride. Cisapride, 5-HT receptor agonist, induces prolongation of QT interval. Additionally, this condition can raise the possibility of...
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Evaluation of the effect of a 0.0584% hydrocortisone aceponate spray on clinical signs and skin barrier function in dogs with atopic dermatitis

Nam EH, Park SH, Jung JY, Han SH, Youn HY, Chae JS, Hwang CY

The purpose of this study was to evaluate the effects of a topical spray containing 0.0584% hydrocortisone aceponate (HCA) on canine atopic dermatitis (CAD) and to evaluate the skin barrier...
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C-reactive protein as an indicator of inflammatory responses to experimentally induced cystitis in dogs

Seo KW, Lee JB, Ahn JO, Lee HW, Hwang CY, Youn HY, Lee CW

The aim of this study was to demonstrate and assess C-reactive protein (CRP) changes in dogs with induced bacterial cystitis with or without antibiotics. We also evaluated availability of CRP...
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