Korean J Parasitol.
2013 Oct;51(5):545-549.
An Autochthonous Case of Canine Visceral Leishmaniasis in Korea
- Affiliations
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- 1Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. cyhwang@snu.ac.kr hyyoun@snu.ac.kr
- 2Department of Veterinary Parasitology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.
- 3BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.
- 4KRF Zoonotic Disease Priority Research Institute, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.
- 5College of Veterinary Medicine, Chonnam National University, Gwangju 500-757, Korea.
- 6Department of Veterinary Clinical Pathology and Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Jeonju 561-756, Korea.
Abstract
- A 12-year-old spayed female mixed-bred dog presented with nasal bleeding of 2 days duration and a skin nodule in the left flank. No abnormalities were found in coagulation profiles and blood pressure. Cytological evaluation of the nodule revealed numerous characteristic round organisms having a nucleus and a bar within macrophages and in the background, consistent with leishmaniasis. In vitro culture was unsuccessful but PCR of the nodular aspirate identified the organisms as Leishmania infantum, and the final diagnosis was canine leishmaniasis. No history of travel to endemic countries was noted. Because the dog had received a blood transfusion 2 years before the illness, serological screening tests were performed in all donor dogs of the commercial blood bank using the commercial Leishmania ELISA test kit, and there were no positive results. Additional 113 dogs with hyperglobulinemia from Seoul were also screened with the same kits but no positive results were obtained. To the best of the author's knowledge this is the first autochthonous case of canine leishmaniasis in Korea.
Keyword
MeSH Terms
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Animals
Base Sequence
DNA, Protozoan/chemistry/genetics
DNA, Ribosomal/chemistry/genetics
Dog Diseases/*diagnosis/epidemiology
Dogs
Enzyme-Linked Immunosorbent Assay/veterinary
Female
Giant Cells/pathology
Leishmania infantum/genetics/immunology/*isolation & purification
Leishmaniasis, Visceral/diagnosis/*veterinary
Molecular Sequence Data
Polymerase Chain Reaction/veterinary
Protozoan Proteins/genetics
Republic of Korea
Sequence Analysis, DNA/veterinary
Serologic Tests/veterinary
DNA, Protozoan
DNA, Ribosomal
Protozoan Proteins
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