- Fibroblast-derived interleukin-6 exacerbates adverse cardiac remodeling after myocardial infarction
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Li H, Bian Y
- KMID: 2555670
- Korean J Physiol Pharmacol.
- 2024 May;28(3):285-294.
- doi: 10.4196/kjpp.2024.28.3.285
Myocardial infarction is one of the leading causes of mortality globally. Currently, the pleiotropic inflammatory cytokine interleukin-6 (IL-6) is considered to be intimately related to the severity of myocardial injury during... -
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- Ferroptosis and its role in gastric and colorectal cancers
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Hou J, Wang B, Li J, Liu W
- KMID: 2555661
- Korean J Physiol Pharmacol.
- 2024 May;28(3):183-196.
- doi: 10.4196/kjpp.2024.28.3.183
Ferroptosis is a novel mechanism of programmed cell death, characterized by intracellular iron overload, intensified lipid peroxidation, and abnormal accumulation of reactive oxygen species, which ultimately resulting in cell membrane... -
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- Cardioprotection via mitochondrial transplantation supports fatty acid metabolism in ischemia-reperfusion injured rat heart
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Jang J, Kang KW, Kim YW, Jeong S, Park J, Park J, Moon J, Jang J, Kim S, Kim S, Cho S, Lee Y, Kim HK, Han J, Ko EA, Jung SC, Kim JH, Ko JH
- KMID: 2555663
- Korean J Physiol Pharmacol.
- 2024 May;28(3):209-217.
- doi: 10.4196/kjpp.2024.28.3.209
In addition to cellular damage, ischemia-reperfusion (IR) injury induces substantial damage to the mitochondria and endoplasmic reticulum. In this study, we sought to determine whether impaired mitochondrial function owing to... -
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- Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients
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Rajan J, Gaur GS, Shanmugavel K, S A
- KMID: 2555667
- Korean J Physiol Pharmacol.
- 2024 May;28(3):253-264.
- doi: 10.4196/kjpp.2024.28.3.253
Chronic neuropathic pain (CNP) is a complex condition often arising from neural maladaptation after nerve injury. Understanding CNP complications involves the intricate interplay between brain-heart dynamics, assessed through quantitative electroencephalogram... -
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- Tivozanib-induced activation of the mitochondrial apoptotic pathway and suppression of epithelial-to-mesenchymal transition in oral squamous cell carcinoma
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Choi NE, Park SC, Kim IR
- KMID: 2555662
- Korean J Physiol Pharmacol.
- 2024 May;28(3):197-207.
- doi: 10.4196/kjpp.2024.28.3.197
The potential of tivozanib as a treatment for oral squamous cell carcinoma (OSCC) was explored in this study. We investigated the effects of tivozanib on OSCC using the Ca9-22 and... -
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- Novel artesunate-metformin conjugate inhibits bladder cancer cell growth associated with Clusterin/SREBP1/FASN signaling pathway
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Lin P, Yang X, Wang L, Zou X, Mu L, Xu C, Yang X
- KMID: 2555664
- Korean J Physiol Pharmacol.
- 2024 May;28(3):219-227.
- doi: 10.4196/kjpp.2024.28.3.219
Bladder cancer remains the 10th most common cancer worldwide. In recent years, metformin has been found to have potential anti-bladder cancer activ- ity while high concentration of IC50 at millimolar level... -
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- Pectolinarigenin ameliorated airway inflammation and airway remodeling to exhibit antitussive effect
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He Q, Liu W, Ma X, Li H, Feng W, Lu X, Li Y, Chen Z
- KMID: 2555665
- Korean J Physiol Pharmacol.
- 2024 May;28(3):229-237.
- doi: 10.4196/kjpp.2024.28.3.229
Cough is a common symptom of several respiratory diseases. However, frequent coughing from acute to chronic often causes great pain to patients. It may turn into cough variant asthma, which... -
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- RNA polymerase I subunit D activated by Yin Yang 1 transcription promote cell proliferation and angiogenesis of colorectal cancer cells
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Shan J, Liang Y, Yang Z, Chen W, Chen Y, Sun K
- KMID: 2555668
- Korean J Physiol Pharmacol.
- 2024 May;28(3):265-273.
- doi: 10.4196/kjpp.2024.28.3.265
This study aims to explore possible effect of RNA polymerase I subunit D (POLR1D) on proliferation and angiogenesis ability of colorectal cancer (CRC) cells and mechanism herein. The correlation of... -
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- Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe
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Mohamed AM, El-Zawahry EYI, Ali MA, Ibrahim DF, Sabry SA, Sarhan OM
- KMID: 2555669
- Korean J Physiol Pharmacol.
- 2024 May;28(3):275-284.
- doi: 10.4196/kjpp.2024.28.3.275
Worldwide, cardiovascular disease is the main cause of death, which accordingly increased by hyperlipidemia. Hyperlipidemia therapy can include lifestyle changes and medications to control cholesterol levels. Statins are the medications... -
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- Dexmedetomidine alleviates blood-brain barrier disruption in rats after cerebral ischemia-reperfusion by suppressing JNK and p38 MAPK signaling
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Zhu C, Wang D, Chang C, Liu A, Zhou J, Yang T, Jiang Y, Li X, Jiang W
- KMID: 2555666
- Korean J Physiol Pharmacol.
- 2024 May;28(3):239-252.
- doi: 10.4196/kjpp.2024.28.3.239
Dexmedetomidine displays multiple mechanisms of neuroprotection in ameliorating ischemic brain injury. In this study, we explored the beneficial effects of dexmedetomidine on blood-brain barrier (BBB) integrity and neuroinflammation in cerebral... -
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