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Recovery of the Spontaneous Erections after Radical Prostatectomy with Early Tadalafil Treatment

Song K, Lee JM, You CH, Hong B, Kim CS, Ahn H, Ahn TY

  • KMID: 2226598
  • Korean J Androl.
  • 2007 Aug;25(2):49-53.
PURPOSE: We evaluated the efficacy of tadalafil for the treatment of erectile dysfunction after nerve-sparing radical prostatectomy. MATERIALS AND METHODS: From April 2004 to February 2005, 28 patients who underwent...
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Effects of Administration of Tadalafil for 24 Weeks on Lower Urinary Tract Symptoms and Erectile Dysfunction

Choi SM, Lee SH, Jeh SU, Kam SC, Hwa JS, Chung KH, Hyun JS

  • KMID: 2298717
  • Korean J Androl.
  • 2007 Dec;25(3):97-102.
PURPOSE: Numerous studies of the effect of tadalafil on sexual function have been performed. However, its effects on lower urinary tract symptoms (LUTS) are unclear. Therefore, the long-term effects of...
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A Case of Tadalafil associated Priapism

Bae JH, Hyun CH, Song PH, Kim HT, Shin HS, Moon KH

  • KMID: 2298780
  • Korean J Androl.
  • 2009 Apr;27(1):59-62.
We report here on a case of priapism that was associated with the use of tadalafil. A 41 year-old-man visited our urology outpatient department with a relapsed erection he'd experienced...
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The Effect of Tadalafil on Gastric Emptying of Healthy Adults

Kim MS, Chang JH, Kim ES, Hwang SJ, Jahng JH, Kim SM, Ryu YH, Park HJ

  • KMID: 2255753
  • Korean J Neurogastroenterol Motil.
  • 2006 Jun;12(1):31-34.
BACKGROUND/AIMS: In a previous study we demonstrated an influence of sildenafil, a phosphodiesterase (PDE) type 5 inhibitor, on intragastric food maldistribution without affecting total gastric emptying. In this we wanted...
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A Case of Central Serous Chorioretinopathy after Tadalafil Treatment

Yoon YS, Lee S, Woo JM, Min JK

PURPOSE: To describe a patient who presented with central serous chorioretinopathy after 2 months of tadalafil administration without any other underlying disease or medication. CASE SUMMARY: A 49-year-old male patient was...
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Effects of Tadalafil on the Cerebral Ischemia-induced Apoptotic Neuronal Cell Death in Motor Cortex of Gerbils

Ko IG, Kim SE, Kim DH, Kim TW, Kim BK, Shin MS, Kim CJ, Na YG, Joo KJ, Kim KH

  • KMID: 2298799
  • Korean J Androl.
  • 2010 Apr;28(1):47-56.
PURPOSE: Cerebral ischemia leads to neuronal cell death, and eventually causes neurological impairments. Tadalafil is a long-acting phosphodiesterase type-5 (PDE-5) inhibitor, and it has been used for the treatment of...
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Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH) and LUTS/BPH with Erectile Dysfunction in Asian Men: A Systematic Review Focusing on Tadalafil

Park HJ, Won JE, Sorsaburu , Rivera PD, Lee SW

  • KMID: 2320815
  • World J Mens Health.
  • 2013 Dec;31(3):193-207.
This review assesses lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) with or without erectile dysfunction (ED) and related therapies focusing on tadalafil. A literature search was...
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Validated UPLC-MS/MS method for the determination of tadalafil in human plasma and its application to a pharmacokinetic study

Kim KY, Nam M, Kwon HJ, Kim KH, Kang SH, Kim SI, Kim CW, Cho SH

A simple, rapid, and reliable UPLC-MS/MS method was developed and validated for the determination of tadalafil in human plasma. The plasma samples were deproteinized with acetonitrile. Chromatographic separation was performed...
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A Case of Acute Pulmonary Thromboembolism after Taking Tadalafil

Lee J, Kwon JH, Lee CH, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Park YS

  • KMID: 2320198
  • Tuberc Respir Dis.
  • 2012 Oct;73(4):231-233.
Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious...
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Serum High-Sensitivity C-Reactive Protein Levels and Response to 5 mg Tadalafil Once Daily in Patients With Erectile Dysfunction and Diabetes

Lee JW, Park HJ, Park NC

  • KMID: 2315943
  • Korean J Urol.
  • 2013 Dec;54(12):858-864.
PURPOSE: We studied the relative importance of high-sensitivity C-reactive protein (hs-CRP) concentrations in patients with erectile dysfunction (ED) and diabetes and determined whether the hs-CRP level predicts the response to...
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Tamsulosin versus tadalafil as a medical expulsive therapy for distal ureteral stones: A prospective randomized study

KC HB, Shrestha A, Acharya GB, Basnet RB, Shah AK, Shrestha P

PURPOSE: This study aimed to compare the safety and efficacy of tamsulosin and tadalafil as medical expulsive therapy for distal ureteral stones. MATERIALS AND METHODS: This prospective randomized study was conducted...
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Open-label, Intermittent Dose, Prospective Study Evaluating the Effects of Tadalafil on Lower Urinary Tract Symptoms and Erectile Function in Patients with Benign Prostatic Hyperplasia: Continuation and Durability of Effects

Kim TB, Kim KH, Yoon SJ

  • KMID: 2232739
  • Int Neurourol J.
  • 2010 Apr;14(1):7-12.
PURPOSE: Benign prostatic hyperplasia is often accompanied by age-related comorbidity, such as erectile dysfunction (ED). Recent data suggest an association between ED and lower urinary tract symptoms (LUTS), and increasing...
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The Efficacy and Safety of Tadalafil 5 mg Once Daily in Korean Men with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: An Integrated Analysis

Lee SW, Paick JS, Park HJ, Won JE, Morisaki Y, Sorsaburu , Viktrup L

  • KMID: 2320807
  • World J Mens Health.
  • 2014 Apr;32(1):28-35.
PURPOSE: This post hoc integrated analysis assessed the efficacy and safety of tadalafil 5 mg once daily in a large Korean population with lower urinary tract symptoms suggestive of benign...
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Treatment persistence with a fixed-dose combination of tadalafil (5 mg) and tamsulosin (0.4 mg) and reasons for early discontinuation in patients with benign prostatic hyperplasia and erectile dysfunction

Ahn ST, Lee DH, Jeong HG, Kim JW, Oh MM, Park HS, Moon DG

PURPOSE: The primary aim of this study was to assess treatment persistence with a fixed-dose combination (FDC) of tadalafil (5 mg) and tamsulosin (0.4 mg). This study also evaluated the...
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Efficacy of phosphodiesterase type 5 inhibitors for the treatment of distal ureteral calculi: A systematic review and meta-analysis

Montes Cardona CE, García-Perdomo HA

PURPOSE: To determine the efficacy of phosphodiesterase type 5 inhibitors (PDE5i) as medical expulsive therapy (MET) for the treatment of distal ureteral calculi. MATERIALS AND METHODS: A search strategy was conducted...
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Safety and Effectiveness of Once-Daily Tadalafil (5 mg) Therapy in Korean Men with Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms in a Real-World Clinical Setting: Results from a Post-Marketing Surveillance Study

Won JE, Chu JY, Choi HC, Chen Y, Park HJ, Dueñas HJ

PURPOSE: The aim of this study was to investigate the safety and effectiveness of tadalafil 5 mg once daily (quaque die [everyday], QD) among Korean men with benign prostatic hyperplasia...
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Efficacy and Safety of Tadalafil 5 mg Administered Once Daily in Korean Men with Erectile Dysfunction: A Prospective, Multicenter Study

Kang DH, Lee JY, Park SY, Moon HS, Jeong TY, Yoo TK, Choi HY, Park HY, Lee TY, Lee SW

  • KMID: 2314630
  • Korean J Urol.
  • 2010 Sep;51(9):647-652.
PURPOSE: The aim of this study was to evaluate the efficacy of a daily dose of tadalafil 5 mg as well as its safety for the cardiovascular system in men...
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A Case of Sexual Enhancer Induced Fixed Drug Eruption

Lee SK, Kim DJ, Suh JH, Kim MS, Lee UH

  • KMID: 2436688
  • Korean J Dermatol.
  • 2018 May;56(4):269-272.
Fixed drug eruption is a commonly reported mucocutaneous drug eruption. A 61-year-old male presented to our clinic with a complaint of an itchy round erythematous patch on the left hand...
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Pharmacokinetics and safety profiles of tadalafil/tamsulosin HCl fixed-dose combination capsule under fasted and fed condition in healthy volunteers

Jin BH, Yoo BW, Oh ES, Yang S, Jung J, Park MS

Co-administration of tadalafil and tamsulosin HCl in patients with benign prostate hyperplasia and erectile dysfunction is increasing in clinical settings. Development of fixed-dose combination (FDC) of tadalafil and tamsulosin HCl...
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A Randomised, Double-Blind, Parallel, Placebo-Controlled Study of the Efficacy and Safety of Tadalafil Administered On-Demand to Men with Erectile Dysfunction in Korea

Choi HK, Kim JJ, Kim SC, Suh J, Park YK, Choi S, Lee WH, Moon KH, Park HY, Park JK, Wang WC, Kopernicky V

PURPOSE: Tadalafil is a phosphodiesterase type 5 inhibitor that is used for the treatment of erectile dysfunction (ED). Previous clinical trials have assessed its efficacy and safety in Western populations,...
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