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Rapid Differentiation of Human Embryonic Stem Cells into Testosterone-Producing Leydig Cell-Like Cells In vitro

Shin EY, Park S, Choi WY, Lee DR

BACKGROUND: Leydig cells (LCs) are testicular somatic cells that are the major producers of testosterone in males. Testosterone is essential for male physiology and reproduction. Reduced testosterone levels lead to hypogonadism...
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Implant survival and risk factor analysis in regenerated bone: results from a 5-year retrospective study

Hong JY, Shin EY, Herr Y, Chung JH, Lim HC, Shin SI

Purpose: The aims of this study were to evaluate the 5-year cumulative survival rate (CSR) of implants placed with guided bone regeneration (GBR) compared to implants placed in native bone,...
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p21-activated kinase 1 is allostericallyInhibited by naphthoquinone (NQ) derivatives

Oh SW, Lee KI, Choi JK, Kim KA, Kim EG, Shin EY

The p21-activated kinases (PAKs) are a family of serine/threonine protein kinases and activated by binding with activated Rho GTPases such as Rac or Cdc42. PAKs regulate actin cytoskeletal remodeling, cell...
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A case involving anesthesia for cesarean section followed by resection of ruptured cavernous malformation of pons :A case report

Park SK, Kang JG, Wie HW, Shin EY

Cavernous malformation is an important cause of cerebral hemorrhage in pregnant women. We experienced a case of cesarean section followed by neurosurgery for resection of ruptured cavernous malformation of pons...
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Hospital Arrival Rate within Golden Time and Factors Influencing Prehospital Delays among Patients with Acute Myocardial Infarction

Ahn HM, Kim H, Lee KS, Lee JH, Jeong HS, Chang SH, Lee KR, Kim SH, Shin EY

PURPOSE: This research was done to identify the hospital arrival rate and factors related to prehospital delay in arriving at an emergency medical center within the golden time after symptom...
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Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain

Kim DJ, Choi CK, Lee CS, Park MH, Tian X, Kim ND, Lee KI, Choi JK, Ahn JH, Shin EY, Shin I, Kim EG

p21-activated kinases (PAKs) are key regulators of actin dynamics, cell proliferation and cell survival. Deregulation of PAK activity contributes to the pathogenesis of various human diseases, including cancer and neurological...
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Test-Retest Reliability of Word Recognition Score Using Korean Standard Monosyllabic Word Lists for Adults as a Function of the Number of Test Words

Kim J, Lee J, Lee KW, Bahng J, Lee JH, Choi CH, Cho SJ, Shin EY, Park J

BACKGROUND AND OBJECTIVES: The purpose was to establish the test-retest reliability of word recognition score (WRS) using Korean standard monosyllabic word lists for adults (KS-MWL-A) recently developed based on the...
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The Effect of Sexual Abuse on Posttraumatic Psychiatric Symptoms in Children and Adolescents with Sexual Abuse

Shin EY, Cheon KA, Jhung K, Song DH, Kim SH

OBJECTIVES: The purpose of this study is to examine the effects of the characteristics of victim and sexual abuse on posttraumatic psychiatric symptoms in children and adolescents with a history...
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Activation of small Rho GTPases by blebbistatin in PC12 cells

Kim EG, Shin EY

  • KMID: 1498922
  • J Biomed Res.
  • 2013 Jun;14(2):60-64.
Neuronal differentiation is a complex biological process accompanying cytoskeletal reorganization, including neurite outgrowth and growth cone formation. Therefore, neuronal differentiation is critically regulated by actin-related signaling proteins, such as small...
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Relationship between White Matter Changes and Cognitive Dysfunction in the Elderly with Subjective Memory Complaint

Shin EY, Jung HY, Kim YR, Lee SI, Kim SG

  • KMID: 2250136
  • Korean J Biol Psychiatry.
  • 2011 Aug;18(3):141-147.
OBJECTIVES: The purpose of this study is to evaluate the relationship between the severity of white matter changes (WMC), risk factors and cognitive domains, including executive function profiles. METHOD: Forty nine...
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Eight Years of Follow-Up Study with Regard to Defense Mechanisms in Medical Students

Shin EY, Jung HY, Lee SI, Kim SG, Park JH

  • KMID: 1456648
  • J Korean Neuropsychiatr Assoc.
  • 2010 May;49(3):332-338.
OBJECTIVES: The purpose of this study was to evaluate the changes in defense mechanisms in medical students as they progress towards becoming a doctor. METHODS: Ninety premedical students were enrolled from...
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Implant failure associated with oral bisphosphonate-related osteonecrosis of the jaw

Shin EY, Kwon YH, Herr Y, Shin SI, Chung JH

PURPOSE: The aim of this study is to report a case of oral bisphosphonate-related osteonecrosis of the jaw (BRONJ) resulting in implant failure. METHODS: A patient suspected of having BRONJ was...
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Comparison of Processed Nerve Allograft and Laminin Derived Peptide Incorporated Nerve Conduit for Peripheral Nerve Regeneration

Lee JY, Choi MH, Shin EY, Min BM, Roh D, Chung DJ

PURPOSE: To compare a processed nerve allograft, laminin derived peptide incorporated nerve conduit, and autograft in terms of electrodiagnostic testing and nerve histomorphometry for peripheral nerve regeneration in a rabbit...
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Correlation of Plasma Homocysteien and Folate Levels with White Matter Changes in Alzheimer's Disease Patients

Kim SG, Jung HY, Lee SY, Shin EY, Jung WY, Park JH

  • KMID: 2334081
  • J Korean Geriatr Psychiatry.
  • 2009 Dec;13(2):83-90.
OBJECTIVES: To explore the relationship of white matter changes (WMC) on magnetic resornance imaging (MRI) with plasma homocysteine and folate levels in Alzheimer's disease (AD) patients. METHODS: Forty-one patients with probable...
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Treatment of Compensatory Hyperhidrosis with Botulinum Toxin A: A case report

Shin SH, Shin EY, Kim DH, Suh JH, Leem JG, Shin JW

Conventional thoracoscopic sympathectomy is an effective method in treating palmar-axillary hyperhidrosis. However, this may result in a postoperatively compensatory hyperhidrosis. Conservative treatments of compensatory hyperhidrosis consist of aluminum chloride, anticholinergics,...
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Cement leakage into subcutaneous tissue after kyphoplasty: A case report

Song JG, Shin EY, Kim DH, Leem JG, Kim YK, Lee C, Shin JW

  • KMID: 2046030
  • Anesth Pain Med.
  • 2009 Oct;4(4):298-301.
We describe a case of cement leakage from the pedicle of vertebrae to the subcutaneous tissue after kyphoplasty.We attempted to remove all cement leakage, but residual cement remained in the...
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Low dose ketamine reduces the induction of ERK1/2 and CREB signaling protein in a neuropathic pain model of rats

Choi JW, In JH, Kim YS, Kang YJ, Lim YG, Cho SM, Shin EY, Joo JD

BACKGROUND: In addition to causing the loss of voluntary sensory and motor function, spinal cord injury (SCI) often creates a state of central neuropathic pain. Rats given SCI display increases...
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Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells

Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG

Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular...
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Lidocaine attenuates the expression of ERK1/2 and CREB in a neuropathic pain model of rats

Joo JD, In JH, Jung HS, Kim YS, Kim DW, Choi WY, Shin EY, Jeon YS

BACKGROUND: In addition to causing the loss of voluntary sensory and motor function, spinal cord injury (SCI) often creates a state of central neuropathic pain. Rats given SCI display increases...
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Effects of Community-based Case Management Program for Clients with Hypertension

So AY, Kim YM, Kim EY, Kim CY, Kim CH, Kim HG, Shin EY, Yoo WS, Yi GM, June KJ

PURPOSE: The purpose of this study was to analyze effects of a community-based case management program for clients with hypertension living in the community. METHODS: The research design was a...
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