J Periodontal Implant Sci.  2010 Apr;40(2):90-95. 10.5051/jpis.2010.40.2.90.

Implant failure associated with oral bisphosphonate-related osteonecrosis of the jaw

• Shin EY
• Kwon YH
• Herr Y
• Shin SI
• Chung JH

• KMID: 1783540
• DOI: http://doi.org/10.5051/jpis.2010.40.2.90

Abstract

PURPOSE
The aim of this study is to report a case of oral bisphosphonate-related osteonecrosis of the jaw (BRONJ) resulting in implant failure.
METHODS
A patient suspected of having BRONJ was referred to the Department of Periodontology, Kyung Hee University School of Dentistry for the evaluation and treatment of exposed bone around implants.
RESULTS
The patient, who had been taking oral bisphosphonates (BPs) for about a year, was successfully treated with systemic antibiotics, chlorhexidine mouth rinse, explantation, and surgical debridement of necrotic bone.
CONCLUSIONS
The results of this case suggest that a patient taking BPs orally should be treated cautiously. Appropriate management including cessation of BPs and respective dental treatment may reduce the development of BRONJ.

Keyword

Bisphosphonates; Osteonecrosis; Osteoporosis

MeSH Terms

Anti-Bacterial Agents
Bisphosphonate-Associated Osteonecrosis of the Jaw
Chlorhexidine
Debridement
Dentistry
Diphosphonates
Humans
Mouth
Osteonecrosis
Osteoporosis
Anti-Bacterial Agents
Chlorhexidine
Diphosphonates