- The Physiologic Roles of the Subepithelial Platelet-derived Growth Factor Receptor alpha-positive Cells in the Colon (Am J Physiol Gastrointest Liver Physiol 2013;304:G823-G834)
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Kim HJ
- KMID: 2381159
- J Neurogastroenterol Motil.
- 2014 Jan;20(1):127-128.
No abstract available. -
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- The Expressions of PDGF-C, PDGF-D and PDGF Receptors in Renal Development Model
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Moon SO, Cho ES, La BJ, Kang KP, Lee S, Sung MJ, Kang SK, Park SK, Kim W
- KMID: 2079441
- Korean J Nephrol.
- 2005 Mar;24(2):170-180.
BACKGROUND: Four platelet derived growth factor (PDGF) family members have been identified; the classical PDGFs, PDGF-A and PDGF-B, and the novel PDGFs, PDGF-C and PDGF-D, which were only recently discovered.... -
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- A Case of Myeloid Neoplasm with a PDGFRB Rearrangement and Eosinophilia
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Cho NG, Kim D, Shim M, Chong SY
- KMID: 2376949
- Korean J Med.
- 2017 Feb;92(1):79-83.
- doi: 10.3904/kjm.2017.92.1.79
Myeloid neoplasia with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) rearrangements is an uncommon Philadelphia-negative myeloproliferative neoplasm. Their most common morphological diagnosis is chronic myelomonocytic leukemia with eosinophilia, which... -
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- Target Therapy for Hepatocellular Carcinoma
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Yoon SK
- KMID: 2168205
- Hanyang Med Rev.
- 2012 May;32(2):118-125.
- doi: 10.7599/hmr.2012.32.2.118
Hepatocellular carcinoma (HCC) is a highly malignant tumor that has limited treatment options in its advanced state. The efficacy of current anti-cancer chemotherapy in advanced HCC has not been satisfactory,... -
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- Expression of Platelet Derived Growth Factor-A, C and Platelet Derived Growth Factor Receptor-alpha in the Ischemia Reperfusion Renal Failure Model
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Kang KP, Kim W, Moon CY, Jang YB, Lee S, Moon SO, Sung MJ, kIm DH, Kang SK, Park SK
- KMID: 2079574
- Korean J Nephrol.
- 2006 Jan;25(1):13-22.
BACKGOUND: Platelet-derived growth factor (PDGF) is a widely expressed growth factor with both mitogenic and chemotactic activities in many connective tissue cell types. There are four members of PDGF family;... -
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- A case of myeloid neoplasm with the PDGFRB rearrangement and eosinophilia
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Jang SE, Kang HJ, Chang YH, Lee DS, Kim HT, Koh KW, Yang SH
- KMID: 2259192
- Korean J Med.
- 2010 Mar;78(3):386-390.
Myeloid neoplasm with the platelet-derived growth factor receptor beta (PDGFRB) rearrangement is a myeloproliferative neoplasm. Patients with this disease often have prominent eosinophilia or monocytosis and the presence of t(5;12)(q31~33;p12)... -
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- Imatinib Mesylate (Gleevec(TM))-induced Lichenoid Drug Eruption Improved by Tentative Dose-reduction and Topical Steroid
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Yang JH, Shin JW, Kim HD, Park YL, Lee SY, Whang KU
- KMID: 2303581
- Korean J Dermatol.
- 2011 Feb;49(2):155-158.
Imatinib mesylate (Gleevec(TM)) is an oral anticancer drug. It works as a selective and competitive inhibitor of tyrosine kinases such as bcr-abl protein, c-kit, and platelet-derived growth factor receptors (PDGFR).... -
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- A Case of Drug Eruption with Periorbital Edema and Exfoliative Dermatitis Induced by Imatinib Mesylate (STI571, Gleevec(TM))
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Joo YH, Min SU, Lee DH, Suh DH
- KMID: 2302247
- Korean J Dermatol.
- 2007 Feb;45(2):194-196.
STI571 (imatinib mesylate, Gleevec(TM)), a selective inhibitor of the bcr-abl, c-kit, platelet-derived growth factor receptor tyrosine kinases, is a new anticancer drug used for chronic myelogenous leukemia and gastrointestinal stromal... -
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- Efficacy of Imatinib in Patients with Platelet-Derived Growth Factor Receptor Alpha-Mutated Gastrointestinal Stromal Tumors
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Yoo C, Ryu MH, Jo J, Park I, Ryoo BY, Kang YK
- KMID: 2454331
- Cancer Res Treat.
- 2016 Apr;48(2):546-552.
- doi: 10.4143/crt.2015.015
PURPOSE: The incidence of gastrointestinal stromal tumors (GISTs) harboring platelet-derived growth factor receptor alpha (PDGFRA) mutations is low, therefore further investigation of the efficacy of imatinib in this subgroup was... -
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- The Significance of Interstitial Cells in Neurogastroenterology
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Blair PJ, Rhee PL, Sanders KM, Ward SM
- KMID: 2381189
- J Neurogastroenterol Motil.
- 2014 Jul;20(3):294-317.
Smooth muscle layers of the gastrointestinal tract consist of a heterogeneous population of cells that include enteric neurons, several classes of interstitial cells of mesenchymal origin, a variety of immune... -
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- Smooth Muscles Contraction in Gastrointestinal Tract and New Concept of Enteric Neurotransmission: Fibroblast-like Cells
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Kim HJ
- KMID: 2264025
- Korean J Med.
- 2011 Sep;81(3):315-321.
This review provides information regarding an enteric neurotransmission from enteric nerve terminals to smooth muscles. In the gastrointestinal tract, phasic contractions are caused by electrical activity termed slow waves. Slow... -
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- Factors Affecting Production of C-reactive Protein in Vascular Smooth Muscle Cells
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Kim SJ, Ryu DR, Kang DH, Choi KB
- KMID: 1465933
- Korean J Nephrol.
- 2009 May;28(3):173-179.
PURPOSE:The stenosis of vascular access for hemodialysis is caused by neointimal hyperplasia with the proliferation of vascular smooth muscle cells (SMC) as a prominent feature. C-reactive protein (CRP) is known... -
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- Ionic Conductance(s) in Response to Post-junctional Potentials
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Koh SD, Rhee PL
- KMID: 2325763
- J Neurogastroenterol Motil.
- 2013 Oct;19(4):426-432.
The gastrointestinal motility is regulated by extrinsic and intrinsic neural regulation. Intrinsic neural pathways are controlled by sensory input, inter-neuronal relay and motor output. Enteric motor neurons release many transmitters... -
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- Mutational Analysis of the Epidermal Growth Factor Receptor Gene in Gastrointestinal Stromal Tumors
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Yoo NJ, Lee JW, Soung YH, Jeon HM, Nam SW, Kim SY, Park WS, Lee JY, Lee SH
- KMID: 2372342
- J Korean Gastric Cancer Assoc.
- 2004 Dec;4(4):268-271.
PUPOSE: Most gastrointestinal stromal tumors (GISTs) have gain-of-function mutations of the KIT or the platelet-derived growth factor receptor alpha (PDGFRA) genes, but approximately 10% of the GISTs are wild types... -
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- The KIT Exon 11 Stop Codon Mutation in Gastrointestinal Stromal Tumors: What Is the Clinical Meaning?
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Michelucci A, Chiappetta C, Cacciotti , Veccia N, Astri E, Leopizzi M, Prosperi Porta R, Petrozza V, Della Rocca C, Bevilacqua G, Cavazzana , Di Cristofano C
- KMID: 2053513
- Gut Liver.
- 2013 Jan;7(1):35-40.
BACKGROUND/AIMS: Gastrointestinal stromal tumors (GISTs) strongly express a receptor tyrosine kinase (RTK, c-KIT-CD117) harboring a KIT mutation that causes constitutive receptor activation leading to the development and growth of tumors;... -
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- Correlations between the Expression of c-Abl, c-Kit, Platelet-derived Growth Factor Receptor (PDGFR)-alpha and PDGFR-beta and Survival in Patients with Ovarian Cancer
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Lee H, Lee KH, Lee KY, Kang CS
- KMID: 2277668
- Korean J Pathol.
- 2006 Jun;40(3):210-216.
BACKGROUND :Protein tyrosine kinases (PTKs) such as c-Abl, c-KIT, PDGFR-alpha and PDGFR-bata are key proteins in the regulation of cell growth. In this study, we evaluated the correlations between the... -
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- Combined Treatment with Anticancer Vaccine Using Genetically Modified Endothelial Cells and Imatinib in Bladder Cancer
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Ha SB, Park YH, Lee E, Ku JH, Kim HH, Kwak C
- KMID: 2315520
- Korean J Urol.
- 2011 May;52(5):327-334.
PURPOSE: We sought to maximize the antitumor effect of an anticancer vaccine based on genetically modified endothelial cells by combining it with the platelet-derived growth factor receptor inhibitor imatinib. MATERIALS AND... -
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- Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties
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Kim EJ, Seo SG, Shin HS, Lee DJ, Kim JH, Lee DY
- KMID: 2412295
- Clin Orthop Surg.
- 2017 Jun;9(2):239-248.
- doi: 10.4055/cios.2017.9.2.239
BACKGROUND: The pericytes in the blood vessel wall have recently been identified to be important in regulating vascular formation, stabilization, remodeling, and function. We isolated and identified pericyte-like platelet-derived growth... -
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- Effect of Retinoic Acid on the Expression of PDGF Receptors During Palatogenesis
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Jang YJ, Park BY, Jung MY, Kwon KT, Kim JY, Jeong YH, Lee YH, Park BK
- KMID: 2092880
- Korean J Anat.
- 2006 Oct;39(5):383-392.
Although cleft lip and palate are one of the most common craniofacial malformation, little is still known about the mechanism of the palate formation. Retinoic acid (RA) is known a teratogen,... -
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- Role of Angiogenic Factors in Airway Remodeling in an Allergic Rhinitis Murine Model
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Moon IJ, Kim DY, Rhee CS, Lee CH, Min YG
- KMID: 2130377
- Allergy Asthma Immunol Res.
- 2012 Jan;4(1):37-45.
- doi: 10.4168/aair.2012.4.1.37
PURPOSE: There is growing evidence that nasal airway remodeling occurs in allergic rhinitis (AR). Although angiogenesis is an important component of airway remodeling in asthma, its involvement in AR has... -
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