- Liquid biopsy? A recent breakthrough in noninvasive bladder cancer surveillance
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Kang M, Ku JH
- KMID: 2427007
- Investig Clin Urol.
- 2016 Sep;57(5):307-308.
- doi: 10.4111/icu.2016.57.5.307
No abstract available. -
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- Gene expression responses in vivo by human telomerase reverse transcriptase (hTERT)-targeting trans-splicing ribozyme
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Song MS, Jeong JS, Cho KS, Lee SW
- KMID: 1091067
- Exp Mol Med.
- 2007 Dec;39(6):722-732.
A trans-splicing ribozyme which can specifically reprogram human telomerase reverse transcriptase (hTERT) RNA was previously suggested as a useful agent for tumor-targeted gene therapy. In this study, we evaluated in... -
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- Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer
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Kim YH, Yan C, Lee IS, Piao XM, Byun YJ, Jeong P, Kim WT, Yun SJ, Kim WJ
- KMID: 2363132
- Investig Clin Urol.
- 2016 Mar;57(2):106-112.
- doi: 10.4111/icu.2016.57.2.106
PURPOSE: Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show... -
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- Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer
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Choi JH, Ahn KS, Kim JG, Hong YS
- KMID: 927130
- Exp Mol Med.
- 2000 Mar;32(1):23-28.
Cytotoxic effect of either cisplatin or p53 gene transfection of lung cancer cells may be different depending on the p53 status of cells. We investigated cytotoxic effects on the combined... -
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- Characterization of aberrant FHIT transcripts in gastric adenocarcinomas
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Lee SH, Kim CJ, Park HK, Koh JW, Cho MH, Baek MJ, Lee MS
- KMID: 938875
- Exp Mol Med.
- 2001 Sep;33(3):124-130.
Aberrant transcripts of FHIT (fragile histidine triad) have been reported in several types of primary tumors and cell lines, including gastric carcinoma. The role of these aberrant transcripts in tumorigenesis... -
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- Different MicroRNA Expression Levels in Gastric Cancer Depending on Helicobacter pylori Infection
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Chang H, Kim N, Park JH, Nam RH, Choi YJ, Lee HS, Yoon H, Shin CM, Park YS, Kim JM, Lee DH
- KMID: 2380763
- Gut Liver.
- 2015 Mar;9(2):188-196.
- doi: 10.5009/gnl13371
BACKGROUND/AIMS: This study was conducted to identify microRNAs (miRNAs) that are differentially expressed in Helicobacter pylori-infected patients with an intestinal type of gastric cancer using miRNA microarray and to confirm... -
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- Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer
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Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY
- KMID: 1109306
- Exp Mol Med.
- 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated... -
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- Urinary Nucleic Acid TSPAN13-to-S100A9 Ratio as a Diagnostic Marker in Prostate Cancer
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Yan C, Kim YH, Kang HW, Seo SP, Jeong P, Lee IS, Kim D, Kim JM, Choi YH, Moon SK, Yun SJ, Kim WJ
- KMID: 2359962
- J Korean Med Sci.
- 2015 Dec;30(12):1784-1792.
- doi: 10.3346/jkms.2015.30.12.1784
The potential use of urinary nucleic acids as diagnostic markers in prostate cancer (PCa) was evaluated. Ninety-five urine samples and 234 prostate tissue samples from patients with PCa and benign... -
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- Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines
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Lee BJ, Lee BH, Wang SG, Lee JC, Roh HJ, Goh EK, Kim CM, Jun ES
- KMID: 1785792
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S73-S78.
- doi: 10.3346/jkms.2007.22.S.S73
Telomerase activity appears to be associated with cell immortalization and malignant progression. Understanding how telomerase activity is regulated in vivo is important not only for understanding the molecular biology of... -
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- The detection of circulating breast cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction
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Bae JW, Choi KH, Kim HG, Park SH
- KMID: 648123
- J Korean Med Sci.
- 2000 Apr;15(2):194-198.
- doi: 10.3346/jkms.2000.15.2.194
Some circulating cancer cells in the blood play a central role in the metastatic process and may have a major influence on patient progress. Their numbers can be very small... -
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- Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution whole-genome oligonucleotide array
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Jung SH, Shin SH, Yim SH, Choi HS, Lee SH, Chung YJ
- KMID: 1058020
- Exp Mol Med.
- 2009 Jul;41(7):462-470.
- doi: 10.3858/emm.2009.41.7.051
Recently, microarray-based comparative genomic hybridization (array-CGH) has emerged as a very efficient technology with higher resolution for the genome-wide identification of copy number alterations (CNA). Although CNAs are thought to... -
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- Prognostic Significance of Multidrug Resistance Gene 1 (MDR1), Multidrug Resistance-related Protein (MRP) and Lung Resistance Protein (LRP) mRNA Expression in Acute Leukemia
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Huh HJ, Park CJ, Jang S, Seo EJ, Chi HS, Lee JH, Lee KH, Seo JJ, Moon HN, Ghim T
- KMID: 1781831
- J Korean Med Sci.
- 2006 Apr;21(2):253-258.
- doi: 10.3346/jkms.2006.21.2.253
The prognostic significance of multidrug resistance (MDR) gene expression is controversial. We investigated whether multidrug resistance gene 1 (MDR1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) mRNA expression... -
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- The role of microRNAs in bladder cancer
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Enokida H, Yoshino H, Matsushita R, Nakagawa M
- KMID: 2426518
- Investig Clin Urol.
- 2016 Jun;57(Suppl 1):S60-S76.
- doi: 10.4111/icu.2016.57.S1.S60
Bladder cancer (BC) is the fifth most common cancer worldwide and is associated with significant morbidity and mortality. The prognosis of muscle invasive BC is poor, and recurrence is common... -
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- Comparison of the Urine ThinPrep Test and Melanoma Antigen Gene RT-PCR for the Detection of Bladder Cancer According to Three Urine Collection Methods
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Kim DY, Cho HJ, Oh HK, Shin IH, Jeon CH
- KMID: 1121660
- Korean J Lab Med.
- 2007 Feb;27(1):50-55.
- doi: 10.3343/kjlm.2007.27.1.50
BACKGROUND: For the detection of transitional cell carcinoma (TCC) of the bladder, we compared the sensitivities and specificities between the ThinPrep test and Melanoma Antigen Gene (MAGE) test with... -
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- Neuronal Apoptosis Inhibitory Protein is Overexpressed in Patients with Unfavorable Prognostic Factors in Breast Cancer
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Choi J, Hwang YK, Choi YJ, Yoo KE, Kim JH, Nam SJ, Yang JH, Lee SJ, Yoo KH, Sung KW, Koo HH, Im YH
- KMID: 1785784
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S17-S23.
- doi: 10.3346/jkms.2007.22.S.S17
Neuronal apoptosis inhibitory protein (NAIP) is a recently identified inhibitor of apoptosis protein. However, the clinical relevance of NAIP expression is not completely understood. In an attempt to determine the... -
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- Expression of Angiopoietin 1, 2 and Their Common Receptor Tie2 in Human Gastric Carcinoma: Implication for Angiogenesis
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Moon WS, Park HS, Yu KH, Jang KY, Kang MJ, Park H, Tarnawski
- KMID: 1781834
- J Korean Med Sci.
- 2006 Apr;21(2):272-278.
- doi: 10.3346/jkms.2006.21.2.272
Angiogenesis, formation of new microvessels providing oxygen and nutrient supply, is essential for tumor growth. It is dependent on the production of angiogenic growth factors by tumor cells. Angiopoietin 1... -
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- Aberrantly expressed microRNAs in the context of bladder tumorigenesis
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Lee JY, Ryu DS, Kim WJ, Kim SJ
- KMID: 2426517
- Investig Clin Urol.
- 2016 Jun;57(Suppl 1):S52-S59.
- doi: 10.4111/icu.2016.57.S1.S52
MicroRNAs (miRNAs), small noncoding RNAs 19-22 nucleotides in length, play a major role in negative regulation of gene expression at the posttranscriptional level. Several miRNAs act as tumor suppressors or... -
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