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Impaired Smooth Pursuit During Transient Global Amnesia

Kim SH, Park YH, Kim S, Kim JS

BACKGROUND AND PURPOSE: During transient global amnesia (TGA), selective impairment of episodic memory is assumed to occur due to alteration in the neuronal network between the hippocampus and parietooccipital cortices...
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Two Cases of Myasthenia Gravis Showing Fatigibility Presenting with Decreased Gain of Smooth Pursuit

Chae JH, Shin HJ, Shin BS, Seo MW, Oh SY

Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies to the acetylcholine receptors of the neuromuscular junction characterized by weakness and abnormal fatigability of the muscles. Therefore, the diagnosis...
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Abnormal Eye Movements in Parkinsonism and Movement Disorders

Jung I, Kim JS

Abnormal eye movements are commonly observed in movement disorders. Ocular motility examination should include bedside evaluation and laboratory recording of ocular misalignment, involuntary eye movements, including nystagmus and saccadic intrusions/oscillations,...
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Association Analysis between Chromogranin B Genetic Variations and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia

Park JW, Pak DH, Hwang MG, Lee MJ, Shin HD, Shin TM, Hahn SW, Hwang J, Lee YJ, Woo SI

OBJECTIVES: According to previous studies, the Chromogranin B (CHGB) gene could be an important candidate gene for schizophrenia which is located on chromosome 20p12.3. Some studies have linked the polymorphism...
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Abnormal Oculomotor Functions in Amyotrophic Lateral Sclerosis

Kang BH, Kim JI, Lim YM, Kim KK

BACKGROUND AND PURPOSE: Although traditionally regarded as spared, a range of oculomotor dysfunction has been recognized in amyotrophic lateral sclerosis (ALS) patients. ALS is nowadays considered as a neurodegenerative disorder...
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Clinical significance of saccade test, smooth pursuit test, and optokinetic nystagmus test in nystagmography

Choi YS, Na HG, Song SY, Kim YD, Bae CH

BACKGROUND: Saccade test, smooth pursuit test, and optokinetic nystagmus test are clinically useful tests to accurately diagnose vertigo. However, there have only been a few studies regarding a correlation between...
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Isolated Infarction of Anterior Cerebellar Vermis

Kim SH, Kim JS

The anterior cerebellar vermis has been known to act in coordination of gait and postural adjustment of the trunk and legs. However, oculomotor abnormalities in an isolated anterior vermian lesion...
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No Association between (AAT)n Repeat Polymorphisms in the Cannabinoid Receptor 1 Gene and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia

Kim MJ, Kim CR, Park JW, Pak DH, Shin HD, Choi IG, Hahn SW, Hwang J, Lee YJ, Woo SI

OBJECTIVES: According to previous studies, the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. Some studies have linked the (AAT)n trinucleotide repeat polymorphism in CNR1...
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Eye Movement Abnormalities and Neuroimaging Findings of Disequilibrium of Unknown Origin

Go JY, Seok JI, Lee DK

  • KMID: 1736999
  • Res Vestib Sci.
  • 2014 Dec;13(4):108-113.
BACKGROUND AND OBJECTIVES: Although disequilibrium is common type of dizziness in older people, it is sometimes difficult to identify a specific cause for this problem. The diffuse brain pathology including...
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Initiation of Smooth Pursuit in Acute Cerebellar Infarction: A Preliminary Study

Yang TH, Oh SY

  • KMID: 1426860
  • Res Vestib Sci.
  • 2013 Jun;12(2):47-53.
BACKGROUND AND OBJECTIVES: The cerebellar lesion causes an initiation deficit of smooth-pursuit eye movement depending on the location of the lesion. We investigated the initiation of smooth pursuit in patients...
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Bedside Evaluation of Dizzy Patients

Huh YE, Kim JS

In recent decades there has been marked progress in the imaging and laboratory evaluation of dizzy patients. However, detailed history taking and comprehensive bedside neurotological evaluation remain crucial for a...
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Congenital Ocular Motor Apraxia: Clinico-Radiological Analyses

Kim JS, Oh YM, Hwang JM, Kim JH

  • KMID: 1454824
  • J Korean Neurol Assoc.
  • 2010 Feb;28(1):27-32.
BACKGROUND: Congenital ocular motor apraxia (COMA) is characterized by impaired voluntary saccades and abnormal head thrusts. However, mechanism of this disorder remains to be elucidated. METHODS: This study analyzed the eye...
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Cerebellar Hypoperfusion during Transient Global Amnesia: An MRI and Oculographic Study

Yang YS, Kim JS, Kim SY, Kim YK, Kwak YT, Han IW

BACKGROUND AND PURPOSE: Transient global amnesia (TGA) is characterized by sudden anterograde and retrograde amnesia lasting for up to 24 hours. Diffusion-weighted magnetic resonance imaging (DWI) in cases of TGA...
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No Association between Val108/158Met Polymorphism on Catechol-O-Methyl Transferase(COMT) Gene and Smooth Pursuit Eye Movement(SPEM) Abnormality in Korean Schizophrenia Patients

Jang HJ, Moon HI, Lee YJ, Kim IY, Lee IS, Seo HG, Kim KH, Shin TM, Park BL, Shin HD, Han SH, Han SW, Woo SI

  • KMID: 2299919
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):288-296.
OBJECTIVES: We investigated the association of Val108/158Met polymorphism on catechol-O-methyl transferase(COMT) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenia patients. METHODS: We measured SPEM in 217 Korean schizophrenia patients(male...
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Clinical and Oculographic Findings of X-linked Congenital Nystagmus in Three Korean Families

Oh SY, Shin BS, Jeong KY, Hwang JM, Kim JS

BACKGROUND AND PURPOSE: Congenital nystagmus (CN) is an ocular oscillation that usually manifests during early infancy. Typical features of CN include bilateral, conjugate, uniplanar, and usually horizontal eye movements, a...
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Lithium-Induced Downbeat Nystagmus with Reversible Splenial Lesion

Kim DU, Lee SH, Jung HJ, Kang KW

  • KMID: 2328962
  • J Korean Bal Soc.
  • 2007 Dec;6(2):150-154.
Lithium is recognized as a cause of reversible or permanent downbeat nystagmus. Many patients who were treated with lithium for psychiatric illness developed downbeat nystagmus and other neurological manifestations. Reversible...
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Ocular Motor Apraxia after Sequential Bilateral Striatal Infarctions

Chung PW, Moon HS, Song HS, Kim YB

Ocular motor apraxia has been reported in bilateral frontoparietal lesions. We report a case of ocular motor apraxia after bilateral striatal infarctions. The patient had impaired voluntary saccades and smooth...
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Perverted Head Shaking Nystagmus due to Cerebellar Lesions: Possible Mechanisms

Oh SY, Choi KD, Kim JM, Kim J, Park SH, Kim JS

  • KMID: 1603824
  • J Korean Bal Soc.
  • 2006 Jun;5(1):35-43.
BACKGROUND AND OBJECTIVES: Perverted head-shaking nystagmus (HSN) refers to nystagmus that develops in the plane other than that being stimulated by head oscillation, i.e., downbeat or upbeat HSN after head...
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Isolated Positional Downbeat Nystagmus: Central or Peripheral Positional Nystagmus?

Oh SY

  • KMID: 1603956
  • J Korean Bal Soc.
  • 2006 Dec;5(2):235-241.
BACKGROUND AND OJBECTIVES: Nystagmus produced by static placement of the head in different orientations is termed positional nystagmus and in most instances the cause is a peripheral vestibular disorder, as...
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Relationship between SNP A and P1763 Polymorphisms on Dystrobrevin Binding Protein 1(DTNBP1) Gene and Smooth Pursuit Eye Movement(SPEM) Abnormality in Korean Schizophrenic Patients

Lee CH, Park BL, Kim LH, Kim DH, Cho SH, Park JS, Kim IY, Lee IS, Seo HG, Byun KO, Kim BJ, Hahn KH, Kim KH, Shin TM, Shin HD, Woo SI

  • KMID: 2299947
  • Korean J Biol Psychiatry.
  • 2006 Nov;13(4):279-288.
OBJECTIVES: We investigated the association of SNP A and P1763 polymorphisms on dystrobrevin binding protein 1(DTNBP1) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenic patients. METHODS: We measured SPEM...
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